-
1
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J (1971) Tumor angiogenesis: Therapeutic implications. N Engl J Med 285 (21):1182-1186.
-
(1971)
N Engl J Med
, vol.285
, Issue.21
, pp. 1182-1186
-
-
Folkman, J.1
-
2
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, et al. (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350(23):2335-2342.
-
(2004)
N Engl J Med
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
-
3
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger DR, et al. (1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219(4587):983-985.
-
(1983)
Science
, vol.219
, Issue.4587
, pp. 983-985
-
-
Senger, D.R.1
-
4
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N (1989) Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246(4935):1306-1309.
-
(1989)
Science
, vol.246
, Issue.4935
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.J.3
Goeddel, D.V.4
Ferrara, N.5
-
5
-
-
30744432619
-
Endothelial cells and VEGF in vascular development
-
Coultas L, Chawengsaksophak K, Rossant J (2005) Endothelial cells and VEGF in vascular development. Nature 438(7070):937-945.
-
(2005)
Nature
, vol.438
, Issue.7070
, pp. 937-945
-
-
Coultas, L.1
Chawengsaksophak, K.2
Rossant, J.3
-
6
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK (2000) Angiogenesis in cancer and other diseases. Nature 407 (6801):249-257.
-
(2000)
Nature
, vol.407
, Issue.6801
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
7
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos GD, et al. (2000) Vascular-specific growth factors and blood vessel formation. Nature 407(6801):242-248.
-
(2000)
Nature
, vol.407
, Issue.6801
, pp. 242-248
-
-
Yancopoulos, G.D.1
-
8
-
-
0037699954
-
The biology of VEGF and its receptors
-
Ferrara N, Gerber HP, LeCouter J (2003) The biology of VEGF and its receptors. Nat Med 9(6):669-676.
-
(2003)
Nat Med
, vol.9
, Issue.6
, pp. 669-676
-
-
Ferrara, N.1
Gerber, H.P.2
LeCouter, J.3
-
9
-
-
66149086950
-
Positive and negative modulation of angiogenesis by VEGFR1 ligands
-
re1
-
Cao Y (2009) Positive and negative modulation of angiogenesis by VEGFR1 ligands. Sci Signal 2(59):re1.
-
(2009)
Sci Signal
, vol.2
, Issue.59
-
-
Cao, Y.1
-
10
-
-
0034042569
-
Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction
-
discussion 205-207
-
Sato Y, et al. (2000) Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction. Ann N Y Acad Sci 902:201-205, discussion 205-207.
-
(2000)
Ann N Y Acad Sci
, vol.902
, pp. 201-205
-
-
Sato, Y.1
-
11
-
-
0036289044
-
Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endothelia
-
Witmer AN, Dai J, Weich HA, Vrensen GF, Schlingemann RO (2002) Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endothelia. J Histochem Cytochem 50(6):767-777.
-
(2002)
J Histochem Cytochem
, vol.50
, Issue.6
, pp. 767-777
-
-
Witmer, A.N.1
Dai, J.2
Weich, H.A.3
Vrensen, G.F.4
Schlingemann, R.O.5
-
12
-
-
0035974803
-
Identification of an angiogenic mitogen selective for endocrine gland endothelium
-
LeCouter J, et al. (2001) Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature 412(6850):877-884.
-
(2001)
Nature
, vol.412
, Issue.6850
, pp. 877-884
-
-
LeCouter, J.1
-
13
-
-
0034522441
-
Paracrine control of the adult adrenal cortex vasculature by vascular endothelial growth factor
-
Vittet D, Ciais D, Keramidas M, De Fraipont F, Feige JJ (2000) Paracrine control of the adult adrenal cortex vasculature by vascular endothelial growth factor. Endocr Res 26 (4):843-852.
-
(2000)
Endocr Res
, vol.26
, Issue.4
, pp. 843-852
-
-
Vittet, D.1
Ciais, D.2
Keramidas, M.3
De Fraipont, F.4
Feige, J.J.5
-
14
-
-
0037465790
-
Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability
-
Eriksson A, et al. (2003) Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability. Circulation 107(11):1532-1538.
-
(2003)
Circulation
, vol.107
, Issue.11
, pp. 1532-1538
-
-
Eriksson, A.1
-
15
-
-
32944474182
-
VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
-
Kamba T, et al. (2006) VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am J Physiol Heart Circ Physiol 290(2):H560-H576.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
, Issue.2
-
-
Kamba, T.1
-
16
-
-
16644377775
-
Overview of bevacizumab: A new cancer therapeutic strategy targeting vascular endothelial growth factor
-
Ignoffo RJ (2004) Overview of bevacizumab: A new cancer therapeutic strategy targeting vascular endothelial growth factor. Am J Health Syst Pharm 61(21, Suppl 5) S21-S26.
-
(2004)
Am J Health Syst Pharm
, vol.61
, Issue.21 SUPPL. 5
-
-
Ignoffo, R.J.1
-
17
-
-
84860148471
-
Bevacizumab in neoadjuvant treatment for breast cancer
-
author reply 1639-1640
-
Miklos GL (2012) Bevacizumab in neoadjuvant treatment for breast cancer. N Engl J Med 366(17):1638, author reply 1639-1640.
-
(2012)
N Engl J Med
, vol.366
, Issue.17
, pp. 1638
-
-
Miklos, G.L.1
-
18
-
-
84859077668
-
Bevacizumab in ovarian cancer
-
author reply 1258
-
Mountzios G, Pentheroudakis G (2012) Bevacizumab in ovarian cancer. N Engl J Med 366(13):1257, author reply 1258.
-
(2012)
N Engl J Med
, vol.366
, Issue.13
, pp. 1257
-
-
Mountzios, G.1
Pentheroudakis, G.2
-
19
-
-
34047186955
-
Bevacizumab for non-small-cell lung cancer
-
author reply 1374-1375
-
Sculier JP, Meert AP, Paesmans M (2007) Bevacizumab for non-small-cell lung cancer. N Engl J Med 356(13):1373-1374, author reply 1374-1375.
-
(2007)
N Engl J Med
, vol.356
, Issue.13
, pp. 1373-1374
-
-
Sculier, J.P.1
Meert, A.P.2
Paesmans, M.3
-
20
-
-
19544391606
-
Bevacizumab in colorectal cancer
-
author reply 1690-1691
-
Sharieff W (2004) Bevacizumab in colorectal cancer. N Engl J Med 351(16):1690-1691; author reply 1690-1691.
-
(2004)
N Engl J Med
, vol.351
, Issue.16
, pp. 1690-1691
-
-
Sharieff, W.1
-
21
-
-
0142120723
-
Bevacizumab in renal-cell cancer
-
Sonpavde G (2003) Bevacizumab in renal-cell cancer. N Engl J Med 349(17):1674.
-
(2003)
N Engl J Med
, vol.349
, Issue.17
, pp. 1674
-
-
Sonpavde, G.1
-
22
-
-
77949407821
-
A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models
-
Yu Y, et al. (2010) A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models. PLoS ONE 5(2):e9072.
-
(2010)
PLoS ONE
, vol.5
, Issue.2
-
-
Yu, Y.1
-
23
-
-
57449113426
-
Anti-VEGF agents confer survival advantages to tumor-bearing mice by improving cancer-Associated systemic syndrome
-
Xue Y, et al. (2008) Anti-VEGF agents confer survival advantages to tumor-bearing mice by improving cancer-Associated systemic syndrome. Proc Natl Acad Sci USA 105 (47):18513-18518.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.47
, pp. 18513-18518
-
-
Xue, Y.1
-
24
-
-
79952769787
-
Antiangiogenic agents significantly improve survival in tumorbearing mice by increasing tolerance to chemotherapy-induced toxicity
-
Zhang D, et al. (2011) Antiangiogenic agents significantly improve survival in tumorbearing mice by increasing tolerance to chemotherapy-induced toxicity. Proc Natl Acad Sci USA 108(10):4117-4122.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.10
, pp. 4117-4122
-
-
Zhang, D.1
-
25
-
-
76249103193
-
VEGFR1-mediated pericyte ablation links VEGF and PlGF to cancerassociated retinopathy
-
Cao R, et al. (2010) VEGFR1-mediated pericyte ablation links VEGF and PlGF to cancerassociated retinopathy. Proc Natl Acad Sci USA 107(2):856-861.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.2
, pp. 856-861
-
-
Cao, R.1
-
26
-
-
84867503535
-
A randomized, double-blind, phase III study of docetaxel and ramucirumab versus docetaxel and placebo in the treatment of stage IV non-smallcell lung cancer after disease progression after 1 previous platinum-based therapy (REVEL): Treatment rationale and study design
-
Garon EB, et al. (2012) A randomized, double-blind, phase III study of docetaxel and ramucirumab versus docetaxel and placebo in the treatment of stage IV non-smallcell lung cancer after disease progression after 1 previous platinum-based therapy (REVEL): Treatment rationale and study design. Clin Lung Cancer 13(6):505-509.
-
(2012)
Clin Lung Cancer
, vol.13
, Issue.6
, pp. 505-509
-
-
Garon, E.B.1
-
27
-
-
0031955877
-
Immunohistochemical localization of vascular endothelial growth factor in the endocrine glands of the rat
-
Fan L, Iseki S (1998) Immunohistochemical localization of vascular endothelial growth factor in the endocrine glands of the rat. Arch Histol Cytol 61(1):17-28.
-
(1998)
Arch Histol Cytol
, vol.61
, Issue.1
, pp. 17-28
-
-
Fan, L.1
Iseki, S.2
-
28
-
-
0018336681
-
Structural aspects of the permeability of the microvascular endothelium
-
Palade GE, Simionescu M, Simionescu N (1979) Structural aspects of the permeability of the microvascular endothelium. Acta Physiol Scand Suppl 463:11-32.
-
(1979)
Acta Physiol Scand Suppl
, vol.463
, pp. 11-32
-
-
Palade, G.E.1
Simionescu, M.2
Simionescu, N.3
-
29
-
-
0018369219
-
Relation of capillary morphology to transport of fluid and large molecules: A review
-
Renkin EM (1979) Relation of capillary morphology to transport of fluid and large molecules: A review. Acta Physiol Scand Suppl 463:81-91.
-
(1979)
Acta Physiol Scand Suppl
, vol.463
, pp. 81-91
-
-
Renkin, E.M.1
-
30
-
-
79951971900
-
Taming glioblastoma by targeting angiogenesis: 3 years later
-
Wong ET, Brem S (2011) Taming glioblastoma by targeting angiogenesis: 3 years later. J Clin Oncol 29(2):124-126.
-
(2011)
J Clin Oncol
, vol.29
, Issue.2
, pp. 124-126
-
-
Wong, E.T.1
Brem, S.2
-
31
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman HS, et al. (2009) Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 27(28):4733-4740.
-
(2009)
J Clin Oncol
, vol.27
, Issue.28
, pp. 4733-4740
-
-
Friedman, H.S.1
-
32
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS (2008) Tumor angiogenesis. N Engl J Med 358(19):2039-2049.
-
(2008)
N Engl J Med
, vol.358
, Issue.19
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
33
-
-
50349083661
-
Antiangiogenic agents and gastrointestinal cancers
-
Lièvre A, Landi B, Mitry E, Taïeb J (2008) [Antiangiogenic agents and gastrointestinal cancers]. Gastroenterol Clin Biol 32(5 Pt 1):504-520.
-
(2008)
Gastroenterol Clin Biol
, vol.32
, Issue.5 PART 1
, pp. 504-520
-
-
Lièvre, A.1
Landi, B.2
Mitry, E.3
Taïeb, J.4
-
34
-
-
77954682879
-
Ramucirumab (IMC-1121B): A novel attack on angiogenesis
-
Spratlin JL, Mulder KE, Mackey JR (2010) Ramucirumab (IMC-1121B): A novel attack on angiogenesis. Future Oncol 6(7):1085-1094.
-
(2010)
Future Oncol
, vol.6
, Issue.7
, pp. 1085-1094
-
-
Spratlin, J.L.1
Mulder, K.E.2
Mackey, J.R.3
-
35
-
-
77649213706
-
Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2
-
Spratlin JL, et al. (2010) Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2. J Clin Oncol 28(5):780-787.
-
(2010)
J Clin Oncol
, vol.28
, Issue.5
, pp. 780-787
-
-
Spratlin, J.L.1
-
36
-
-
84867602821
-
Aflibercept and Docetaxel versus Docetaxel alone after platinum failure in patients with advanced or metastatic non-small-cell lung cancer: A randomized, controlled phase III trial
-
Ramlau R, et al. (2012) Aflibercept and Docetaxel versus Docetaxel alone after platinum failure in patients with advanced or metastatic non-small-cell lung cancer: A randomized, controlled phase III trial. J Clin Oncol 30(29):3640-3647.
-
(2012)
J Clin Oncol
, vol.30
, Issue.29
, pp. 3640-3647
-
-
Ramlau, R.1
-
37
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, et al. (2007) Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 356(2):115-124.
-
(2007)
N Engl J Med
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
-
38
-
-
33846148701
-
Sorafenib in advanced clear-cell renalcell carcinoma
-
TARGET Study Group
-
Escudier B, et al.; TARGET Study Group (2007) Sorafenib in advanced clear-cell renalcell carcinoma. N Engl J Med 356(2):125-134.
-
(2007)
N Engl J Med
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
-
39
-
-
84861100374
-
Pazopanib and the treatment palette for soft-tissue sarcoma
-
Bramwell VH (2012) Pazopanib and the treatment palette for soft-tissue sarcoma. Lancet 379(9829):1854-1856.
-
(2012)
Lancet
, vol.379
, Issue.9829
, pp. 1854-1856
-
-
Bramwell, V.H.1
-
40
-
-
84856027412
-
Cardiovascular toxicity of antiangiogenic drugs
-
des Guetz G, Uzzan B, Chouahnia K, Morère JF (2011) Cardiovascular toxicity of antiangiogenic drugs. Target Oncol 6(4):197-202.
-
(2011)
Target Oncol
, vol.6
, Issue.4
, pp. 197-202
-
-
Des Guetz, G.1
Uzzan, B.2
Chouahnia, K.3
Morère, J.F.4
-
41
-
-
77951937790
-
Bevacizumab toxicities and their management in ovarian cancer
-
Randall LM, Monk BJ (2010) Bevacizumab toxicities and their management in ovarian cancer. Gynecol Oncol 117(3):497-504.
-
(2010)
Gynecol Oncol
, vol.117
, Issue.3
, pp. 497-504
-
-
Randall, L.M.1
Monk, B.J.2
-
42
-
-
45849103519
-
Gastrointestinal ulceration as a possible side effect of bevacizumab which may herald perforation
-
Tol J, et al. (2008) Gastrointestinal ulceration as a possible side effect of bevacizumab which may herald perforation. Invest New Drugs 26(4):393-397.
-
(2008)
Invest New Drugs
, vol.26
, Issue.4
, pp. 393-397
-
-
Tol, J.1
-
43
-
-
79955726432
-
Review: Thyroid function abnormalities in patients receiving VEGFtargeted therapy
-
Rini BI (2011) Review: Thyroid function abnormalities in patients receiving VEGFtargeted therapy. Clin Adv Hematol Oncol 9(4):337-338.
-
(2011)
Clin Adv Hematol Oncol
, vol.9
, Issue.4
, pp. 337-338
-
-
Rini, B.I.1
-
44
-
-
33749441325
-
Rapid vascular regrowth in tumors after reversal of VEGF inhibition
-
Mancuso MR, et al. (2006) Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest 116(10):2610-2621.
-
(2006)
J Clin Invest
, vol.116
, Issue.10
, pp. 2610-2621
-
-
Mancuso, M.R.1
-
45
-
-
36749052895
-
Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy
-
Ebos JM, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS (2007) Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy. Proc Natl Acad Sci USA 104(43):17069-17074.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.43
, pp. 17069-17074
-
-
Ebos, J.M.1
Lee, C.R.2
Christensen, J.G.3
Mutsaers, A.J.4
Kerbel, R.S.5
-
46
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D, Itin A, Soffer D, Keshet E (1992) Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359(6398): 843-845.
-
(1992)
Nature
, vol.359
, Issue.6398
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
47
-
-
0035969508
-
Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression
-
Makino Y, et al. (2001) Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression. Nature 414(6863):550-554.
-
(2001)
Nature
, vol.414
, Issue.6863
, pp. 550-554
-
-
Makino, Y.1
-
48
-
-
57349138859
-
Hypertension and proteinuria: A class-effect of antiangiogenic therapies
-
Launay-Vacher V, Deray G (2009) Hypertension and proteinuria: A class-effect of antiangiogenic therapies. Anticancer Drugs 20(1):81-82.
-
(2009)
Anticancer Drugs
, vol.20
, Issue.1
, pp. 81-82
-
-
Launay-Vacher, V.1
Deray, G.2
-
49
-
-
33846638744
-
Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-Analysis
-
Zhu X, Wu S, Dahut WL, Parikh CR (2007) Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-Analysis. Am J Kidney Dis 49(2):186-193.
-
(2007)
Am J Kidney Dis
, vol.49
, Issue.2
, pp. 186-193
-
-
Zhu, X.1
Wu, S.2
Dahut, W.L.3
Parikh, C.R.4
-
50
-
-
84855466019
-
A phase 3 trial of bevacizumab in ovarian cancer
-
ICON7 Investigators
-
Perren TJ, et al.; ICON7 Investigators (2011) A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med 365(26):2484-2496.
-
(2011)
N Engl J Med
, vol.365
, Issue.26
, pp. 2484-2496
-
-
Perren, T.J.1
|