Rosmarinic acid down-regulates endothelial protein C receptor shedding in vitro and in vivo

Food and Chemical Toxicology

Volumn 59, Issue , 2013, Pages 311-315

  Ku, Sae Kwang ^a   Yang, Eun Ju ^b   Song, Kyung Sik ^c   Bae, Jong Sup ^c  

^a Daegu Haany University   (South Korea)

^b BK21 Research Team for Developing Functional Health Food Materials   (South Korea)

^c Kyungpook National University   (South Korea)

Author keywords

CLP; EPCR; PMA; Rosmarinic acid; Shedding

Indexed keywords

ENDOTHELIAL PROTEIN C RECEPTOR; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; ROSMARINIC ACID; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MEDICAL PROCEDURES; MOUSE; NONHUMAN; PERILLA FRUTESCENS; PLANT LEAF; RECEPTOR DOWN REGULATION; SEPTICEMIA; SINGLE DRUG DOSE; VASCULAR DISEASE;

CLP; EPCR; PMA; ROSMARINIC ACID; SHEDDING;

ADAM PROTEINS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIGENS, CD; CELLS, CULTURED; CINNAMATES; DEPSIDES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; RECEPTORS, CELL SURFACE; SEPSIS; SOLUBILITY;

EID: 84880359335     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.06.003     Document Type: Article

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