Iron depletion increases manganese uptake and potentiates apoptosis through ER stress

NeuroToxicology

Volumn 38, Issue , 2013, Pages 67-73

  Seo, Young Ah ^a   Li, Yuan ^a   Wessling Resnick, Marianne ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

DMT1; Endoplasmic reticulum; Iron deficiency; SH SY5Y cells

Indexed keywords

CASPASE 12; CASPASE 3; DEFEROXAMINE; GLUCOSE REGULATED PROTEIN 94; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; MANGANESE; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE INDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IRON DEFICIENCY; IRON DEPLETION; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; UNFOLDED PROTEIN RESPONSE;

DMT1; ENDOPLASMIC RETICULUM; IRON DEFICIENCY; SH-SY5Y CELLS;

ANIMALS; APOPTOSIS; CASPASE 12; CASPASE 3; CELL LINE; CELL SURVIVAL; DEFEROXAMINE; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IRON; MANGANESE; MEMBRANE PROTEINS; RATS; TRANSCRIPTION FACTOR CHOP;

EID: 84880344474     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2013.06.002     Document Type: Article

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