-
1
-
-
14544270984
-
Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates
-
15744308 10.1038/nature03329 1:CAS:528:DC%2BD2MXhslClsLY%3D
-
Loog M, Morgan DO (2005) Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates. Nature 434:104-108
-
(2005)
Nature
, vol.434
, pp. 104-108
-
-
Loog, M.1
Morgan, D.O.2
-
2
-
-
16544391184
-
Cell division: The heart of the cycle
-
15577895 10.1038/432564a 1:CAS:528:DC%2BD2cXhtVeht7zE
-
Lukas J, Bartek J (2004) Cell division: the heart of the cycle. Nature 432:564-567
-
(2004)
Nature
, vol.432
, pp. 564-567
-
-
Lukas, J.1
Bartek, J.2
-
3
-
-
33846523617
-
Targeted anti-mitotic therapies: Can we improve on tubulin agents?
-
17251917 10.1038/nrc2049 1:CAS:528:DC%2BD2sXotFOjtA%3D%3D
-
Jackson JR, Patrick DR, Dar MM, Huang PS (2007) Targeted anti-mitotic therapies: can we improve on tubulin agents? Nat Rev Cancer 7:107-117
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 107-117
-
-
Jackson, J.R.1
Patrick, D.R.2
Dar, M.M.3
Huang, P.S.4
-
4
-
-
34548814434
-
Mitotic drug targets and the development of novel anti-mitotic anticancer drugs
-
17669681 10.1016/j.drup.2007.06.003 1:CAS:528:DC%2BD2sXhtFWhs73N
-
Schmidt M, Bastians H (2007) Mitotic drug targets and the development of novel anti-mitotic anticancer drugs. Drug Resist Updat 10:162-181
-
(2007)
Drug Resist Updat
, vol.10
, pp. 162-181
-
-
Schmidt, M.1
Bastians, H.2
-
5
-
-
69549120405
-
How do anti-mitotic drugs kill cancer cells?
-
19625502 10.1242/jcs.039719 1:CAS:528:DC%2BD1MXhtVGhsL7F
-
Gascoigne KE, Taylor SS (2009) How do anti-mitotic drugs kill cancer cells? J Cell Sci 122:2579-2585
-
(2009)
J Cell Sci
, vol.122
, pp. 2579-2585
-
-
Gascoigne, K.E.1
Taylor, S.S.2
-
6
-
-
0037313516
-
Molecular imaging in drug discovery and development
-
12563303 10.1038/nrd1007 1:CAS:528:DC%2BD3sXot12muw%3D%3D
-
Rudin M, Weissleder R (2003) Molecular imaging in drug discovery and development. Nat Rev Drug Discov 2:123-131
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 123-131
-
-
Rudin, M.1
Weissleder, R.2
-
7
-
-
0036233675
-
Developmental therapeutics program at the NCI: Molecular target and drug discovery process
-
11960328 10.1038/sj.leu.2402464 1:CAS:528:DC%2BD38XjvFGnurc%3D
-
Monga M, Sausville EA (2002) Developmental therapeutics program at the NCI: molecular target and drug discovery process. Leukemia 16:520-526
-
(2002)
Leukemia
, vol.16
, pp. 520-526
-
-
Monga, M.1
Sausville, E.A.2
-
8
-
-
34447528673
-
Optical molecular imaging in drug discovery and clinical development
-
23496038 10.1517/17460441.2.1.65 1:CAS:528:DC%2BD2sXhs1Sitr0%3D
-
Bednar B, Zhang GJ, Williams DL, Hargreaves R, Sur C (2007) Optical molecular imaging in drug discovery and clinical development. Expert Opin Drug Discov 2:65-85
-
(2007)
Expert Opin Drug Discov
, vol.2
, pp. 65-85
-
-
Bednar, B.1
Zhang, G.J.2
Williams, D.L.3
Hargreaves, R.4
Sur, C.5
-
9
-
-
0029365999
-
Cell cycle. the only way out of mitosis
-
8542285 10.1016/S0960-9822(95)00190-4 1:CAS:528:DyaK2MXotVSgtrY%3D
-
Glotzer M (1995) Cell cycle. The only way out of mitosis. Curr Biol 5:970-972
-
(1995)
Curr Biol
, vol.5
, pp. 970-972
-
-
Glotzer, M.1
-
10
-
-
0029051233
-
Cyclin ubiquitination: The destructive end of mitosis
-
7736567 10.1016/0092-8674(95)90322-4 1:CAS:528:DyaK2MXlt1Kju7o%3D
-
Murray A (1995) Cyclin ubiquitination: the destructive end of mitosis. Cell 81:149-152
-
(1995)
Cell
, vol.81
, pp. 149-152
-
-
Murray, A.1
-
11
-
-
1642399624
-
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
-
15014503 10.1038/nature02381 1:CAS:528:DC%2BD2cXhvFCls70%3D
-
Wei W, Ayad NG, Wan Y, Zhang GJ, Kirschner MW et al (2004) Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex. Nature 428:194-198
-
(2004)
Nature
, vol.428
, pp. 194-198
-
-
Wei, W.1
Ayad, N.G.2
Wan, Y.3
Zhang, G.J.4
Kirschner, M.W.5
-
12
-
-
34548591160
-
Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP
-
17804233 10.1016/j.bmcl.2007.07.067 1:CAS:528:DC%2BD2sXhtVGisb%2FK
-
Garbaccio RM, Tasber ES, Neilson LA, Coleman PJ, Fraley ME et al (2007) Kinesin spindle protein (KSP) inhibitors. Part 7: design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett 17:5671-5676
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 5671-5676
-
-
Garbaccio, R.M.1
Tasber, E.S.2
Neilson, L.A.3
Coleman, P.J.4
Fraley, M.E.5
-
13
-
-
34548289035
-
Optical imaging of tumor cells in hollow fibers: Evaluation of the antitumor activities of anticancer drugs and target validation
-
17786184 10.1593/neo.07421 1:CAS:528:DC%2BD2sXhtV2nsrfN
-
Zhang GJ, Chen TB, Bednar B, Connolly BM, Hargreaves R et al (2007) Optical imaging of tumor cells in hollow fibers: evaluation of the antitumor activities of anticancer drugs and target validation. Neoplasia 9:652-661
-
(2007)
Neoplasia
, vol.9
, pp. 652-661
-
-
Zhang, G.J.1
Chen, T.B.2
Bednar, B.3
Connolly, B.M.4
Hargreaves, R.5
-
14
-
-
2942755714
-
Bioluminescent imaging of Cdk2 inhibition in vivo
-
15122251 10.1038/nm1047 1:CAS:528:DC%2BD2cXksVaisrk%3D
-
Zhang GJ, Safran M, Wei W, Sorensen E, Lassota P et al (2004) Bioluminescent imaging of Cdk2 inhibition in vivo. Nat Med 10:643-648
-
(2004)
Nat Med
, vol.10
, pp. 643-648
-
-
Zhang, G.J.1
Safran, M.2
Wei, W.3
Sorensen, E.4
Lassota, P.5
-
15
-
-
22244459880
-
Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage
-
16023598 10.1016/j.ccr.2005.06.003 1:CAS:528:DC%2BD2MXntVejs7s%3D
-
Tao W, South VJ, Zhang Y, Davide JP, Farrell L et al (2005) Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage. Cancer Cell 8:49-59
-
(2005)
Cancer Cell
, vol.8
, pp. 49-59
-
-
Tao, W.1
South, V.J.2
Zhang, Y.3
Davide, J.P.4
Farrell, L.5
-
16
-
-
13244268317
-
Dynamic in vivo imaging and cell tracking using a histone fluorescent protein fusion in mice
-
15619330 10.1186/1472-6750-4-33
-
Hadjantonakis AK, Papaioannou VE (2004) Dynamic in vivo imaging and cell tracking using a histone fluorescent protein fusion in mice. BMC Biotechnol 4:33
-
(2004)
BMC Biotechnol
, vol.4
, pp. 33
-
-
Hadjantonakis, A.K.1
Papaioannou, V.E.2
-
17
-
-
0141976400
-
Bioluminescent molecular imaging of endogenous and exogenous p53-mediated transcription in vitro and in vivo using an HCT116 human colon carcinoma xenograft model
-
12750563
-
Wang W, El-Deiry WS (2003) Bioluminescent molecular imaging of endogenous and exogenous p53-mediated transcription in vitro and in vivo using an HCT116 human colon carcinoma xenograft model. Cancer Biol Ther 2:196-202
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 196-202
-
-
Wang, W.1
El-Deiry, W.S.2
-
18
-
-
0038378519
-
Imaging 26S proteasome activity and inhibition in living mice
-
12819780 10.1038/nm894 1:CAS:528:DC%2BD3sXkvFOjsbg%3D
-
Luker GD, Pica CM, Song J, Luker KE, Piwnica-Worms D (2003) Imaging 26S proteasome activity and inhibition in living mice. Nat Med 9:969-973
-
(2003)
Nat Med
, vol.9
, pp. 969-973
-
-
Luker, G.D.1
Pica, C.M.2
Song, J.3
Luker, K.E.4
Piwnica-Worms, D.5
-
19
-
-
0029004815
-
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
-
7736580 10.1016/0092-8674(95)90338-0 1:CAS:528:DyaK2MXlt1Kis74%3D
-
King RW, Peters JM, Tugendreich S, Rolfe M, Hieter P et al (1995) A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81:279-288
-
(1995)
Cell
, vol.81
, pp. 279-288
-
-
King, R.W.1
Peters, J.M.2
Tugendreich, S.3
Rolfe, M.4
Hieter, P.5
-
20
-
-
0032189040
-
The role of the destruction box and its neighbouring lysine residues in cyclin B for anaphase ubiquitin-dependent proteolysis in fission yeast: Defining the D-box receptor
-
9755167 10.1093/emboj/17.19.5670 1:CAS:528:DyaK1cXmvVyjsL4%3D
-
Yamano H, Tsurumi C, Gannon J, Hunt T (1998) The role of the destruction box and its neighbouring lysine residues in cyclin B for anaphase ubiquitin-dependent proteolysis in fission yeast: defining the D-box receptor. EMBO J 17:5670-5678
-
(1998)
EMBO J
, vol.17
, pp. 5670-5678
-
-
Yamano, H.1
Tsurumi, C.2
Gannon, J.3
Hunt, T.4
-
21
-
-
0033166064
-
Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal
-
10395539 10.1016/S0960-9822(99)80308-X 1:CAS:528:DyaK1MXktlOqt7Y%3D
-
Hagting A, Jackman M, Simpson K, Pines J (1999) Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal. Curr Biol 9:680-689
-
(1999)
Curr Biol
, vol.9
, pp. 680-689
-
-
Hagting, A.1
Jackman, M.2
Simpson, K.3
Pines, J.4
-
22
-
-
0033592688
-
Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex
-
10548110 10.1038/44611 1:CAS:528:DyaK1MXntFaqt7s%3D
-
Lukas C, Sorensen CS, Kramer E, Santoni-Rugiu E, Lindeneg C et al (1999) Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex. Nature 401:815-818
-
(1999)
Nature
, vol.401
, pp. 815-818
-
-
Lukas, C.1
Sorensen, C.S.2
Kramer, E.3
Santoni-Rugiu, E.4
Lindeneg, C.5
-
23
-
-
35748945448
-
The role of Aurora-A inhibitors in cancer therapy
-
17591831 10.1093/annonc/mdm224
-
Agnese V, Bazan V, Fiorentino FP, Fanale D, Badalamenti G et al (2007) The role of Aurora-A inhibitors in cancer therapy. Ann Oncol 18(Suppl 6):vi47-vi52
-
(2007)
Ann Oncol
, vol.18
, Issue.SUPPL. 6
-
-
Agnese, V.1
Bazan, V.2
Fiorentino, F.P.3
Fanale, D.4
Badalamenti, G.5
-
24
-
-
38849199681
-
Visualizing spatiotemporal dynamics of multicellular cell-cycle progression
-
18267078 10.1016/j.cell.2007.12.033 1:CAS:528:DC%2BD1cXivVahurc%3D
-
Sakaue-Sawano A, Kurokawa H, Morimura T, Hanyu A, Hama H et al (2008) Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell 132:487-498
-
(2008)
Cell
, vol.132
, pp. 487-498
-
-
Sakaue-Sawano, A.1
Kurokawa, H.2
Morimura, T.3
Hanyu, A.4
Hama, H.5
|