-
1
-
-
0032952010
-
Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
-
Benjamin LE, Golijanin D, Itin A, Pode D, Keshet E (1999) Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest 103: 159-165.
-
(1999)
J Clin Invest
, vol.103
, pp. 159-165
-
-
Benjamin, L.E.1
Golijanin, D.2
Itin, A.3
Pode, D.4
Keshet, E.5
-
2
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers G, Hanahan D (2008) Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 8: 592-603.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
3
-
-
0038376002
-
Molecular regulation of vessel maturation
-
Jain RK (2003) Molecular regulation of vessel maturation. Nat Med 9: 685-693.
-
(2003)
Nat Med
, vol.9
, pp. 685-693
-
-
Jain, R.K.1
-
4
-
-
27644557532
-
The role of pericytes in blood-vessel formation and maintenance
-
Bergers G, Song S (2005) The role of pericytes in blood-vessel formation and maintenance. Neuro Oncol 7: 452-464.
-
(2005)
Neuro Oncol
, vol.7
, pp. 452-464
-
-
Bergers, G.1
Song, S.2
-
5
-
-
34249689753
-
Molecular regulation of angiogenesis and lymphangiogenesis
-
Adams RH, Alitalo K (2007) Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol 8: 464-478.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 464-478
-
-
Adams, R.H.1
Alitalo, K.2
-
6
-
-
41449101847
-
Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-beta in vascular morphogenesis
-
Holderfield MT, Hughes CC (2008) Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-beta in vascular morphogenesis. Circ Res 102: 637-652.
-
(2008)
Circ Res
, vol.102
, pp. 637-652
-
-
Holderfield, M.T.1
Hughes, C.C.2
-
7
-
-
33847344251
-
Review of the pericyte during angiogenesis and its role in cancer and diabetic retinopathy
-
Hall AP (2006) Review of the pericyte during angiogenesis and its role in cancer and diabetic retinopathy. Toxicol Pathol 34: 763-775.
-
(2006)
Toxicol Pathol
, vol.34
, pp. 763-775
-
-
Hall, A.P.1
-
8
-
-
0035972251
-
Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis
-
Hellstrom M, Gerhardt H, Kalen M, Li X, Eriksson U, et al. (2001) Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol 153: 543-553.
-
(2001)
J Cell Biol
, vol.153
, pp. 543-553
-
-
Hellstrom, M.1
Gerhardt, H.2
Kalen, M.3
Li, X.4
Eriksson, U.5
-
9
-
-
1642321880
-
Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy
-
Wilkinson-Berka JL, Babic S, De Gooyer T, Stitt AW, Jaworski K, et al. (2004) Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy. Am J Pathol 164: 1263-1273.
-
(2004)
Am J Pathol
, vol.164
, pp. 1263-1273
-
-
Wilkinson-Berka, J.L.1
Babic, S.2
De Gooyer, T.3
Stitt, A.W.4
Jaworski, K.5
-
10
-
-
57649135172
-
A role for VEGF as a negative regulator of pericyte function and vessel maturation
-
Greenberg JI, Shields DJ, Barillas SG, Acevedo LM, Murphy E, et al. (2008) A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature 456: 809-813.
-
(2008)
Nature
, vol.456
, pp. 809-813
-
-
Greenberg, J.I.1
Shields, D.J.2
Barillas, S.G.3
Acevedo, L.M.4
Murphy, E.5
-
11
-
-
12344312042
-
Cellular abnormalities of blood vessels as targets in cancer
-
Baluk P, Hashizume H, McDonald DM (2005) Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev 15: 102-111.
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 102-111
-
-
Baluk, P.1
Hashizume, H.2
McDonald, D.M.3
-
12
-
-
33750330092
-
Localization of Ang-1, -2, Tie-2, and VEGF expression at endothelial-pericyte interdigitation in rat angiogenesis
-
Wakui S, Yokoo K, Muto T, Suzuki Y, Takahashi H, et al. (2006) Localization of Ang-1, -2, Tie-2, and VEGF expression at endothelial-pericyte interdigitation in rat angiogenesis. Lab Invest 86: 1172-1184.
-
(2006)
Lab Invest
, vol.86
, pp. 1172-1184
-
-
Wakui, S.1
Yokoo, K.2
Muto, T.3
Suzuki, Y.4
Takahashi, H.5
-
13
-
-
0023585264
-
Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells
-
Orlidge A, D'Amore PA (1987) Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells. J Cell Biol 105: 1455-1462.
-
(1987)
J Cell Biol
, vol.105
, pp. 1455-1462
-
-
Orlidge, A.1
D'Amore, P.A.2
-
14
-
-
8144221439
-
Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation
-
Ding R, Darland DC, Parmacek MS, D'Amore PA (2004) Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation. Stem Cells Dev 13: 509-520.
-
(2004)
Stem Cells Dev
, vol.13
, pp. 509-520
-
-
Ding, R.1
Darland, D.C.2
Parmacek, M.S.3
D'Amore, P.A.4
-
15
-
-
0030851764
-
Signaling vascular morphogenesis and maintenance
-
Hanahan D (1997) Signaling vascular morphogenesis and maintenance. Science 277: 48-50.
-
(1997)
Science
, vol.277
, pp. 48-50
-
-
Hanahan, D.1
-
16
-
-
0036896814
-
Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells
-
Uemura A, Ogawa M, Hirashima M, Fujiwara T, Koyama S, et al. (2002) Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells. J Clin Invest 110: 1619-1628.
-
(2002)
J Clin Invest
, vol.110
, pp. 1619-1628
-
-
Uemura, A.1
Ogawa, M.2
Hirashima, M.3
Fujiwara, T.4
Koyama, S.5
-
17
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, et al. (1997) Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277: 55-60.
-
(1997)
Science
, vol.277
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
-
18
-
-
0035121532
-
Blood vessel maturation in a 3-dimensional spheroidal coculture model: Direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness
-
Korff T, Kimmina S, Martiny-Baron G, Augustin HG (2001) Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness. Faseb J 15: 447-457.
-
(2001)
Faseb J
, vol.15
, pp. 447-457
-
-
Korff, T.1
Kimmina, S.2
Martiny-Baron, G.3
Augustin, H.G.4
-
19
-
-
23444460271
-
Antiangiogenic therapy for cancer: Current and emerging concepts
-
Jain RK (2005) Antiangiogenic therapy for cancer: current and emerging concepts. Oncology (Williston Park) 19: 7-16.
-
(2005)
Oncology (Williston Park)
, vol.19
, pp. 7-16
-
-
Jain, R.K.1
-
20
-
-
2542628099
-
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
-
Tong RT, Boucher Y, Kozin SV, Winkler F, Hicklin DJ, et al. (2004) Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res 64: 3731-3736.
-
(2004)
Cancer Res
, vol.64
, pp. 3731-3736
-
-
Tong, R.T.1
Boucher, Y.2
Kozin, S.V.3
Winkler, F.4
Hicklin, D.J.5
-
21
-
-
52049085327
-
Pericyte isolation and use in endothelial/ pericyte coculture models
-
Bryan BA, D'Amore PA (2008) Pericyte isolation and use in endothelial/ pericyte coculture models. Methods Enzymol 443: 315-331.
-
(2008)
Methods Enzymol
, vol.443
, pp. 315-331
-
-
Bryan, B.A.1
D'Amore, P.A.2
-
22
-
-
0035671571
-
Comparison of three in vitro human 'angiogenesis' assays with capillaries formed in vivo
-
Donovan D, Brown NJ, Bishop ET, Lewis CE (2001) Comparison of three in vitro human 'angiogenesis' assays with capillaries formed in vivo. Angiogenesis 4: 113-121.
-
(2001)
Angiogenesis
, vol.4
, pp. 113-121
-
-
Donovan, D.1
Brown, N.J.2
Bishop, E.T.3
Lewis, C.E.4
-
23
-
-
33644683263
-
Endothelial extracellular matrix: Biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization
-
Davis GE, Senger DR (2005) Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ Res 97: 1093-1107.
-
(2005)
Circ Res
, vol.97
, pp. 1093-1107
-
-
Davis, G.E.1
Senger, D.R.2
-
24
-
-
0001505189
-
An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes
-
Antonelli-Orlidge A, Saunders KB, Smith SR, D'Amore PA (1989) An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes. Proc Natl Acad Sci U S A 86: 4544-4548.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 4544-4548
-
-
Antonelli-Orlidge, A.1
Saunders, K.B.2
Smith, S.R.3
D'Amore, P.A.4
-
25
-
-
0036325594
-
Rac regulates endothelial morphogenesis and capillary assembly
-
Connolly JO, Simpson N, Hewlett L, Hall A (2002) Rac regulates endothelial morphogenesis and capillary assembly. Mol Biol Cell 13: 2474-2485.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2474-2485
-
-
Connolly, J.O.1
Simpson, N.2
Hewlett, L.3
Hall, A.4
-
26
-
-
0242456268
-
Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival
-
Darland DC, Massingham LJ, Smith SR, Piek E, Saint-Geniez M, et al. (2003) Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival. Dev Biol 264: 275-288.
-
(2003)
Dev Biol
, vol.264
, pp. 275-288
-
-
Darland, D.C.1
Massingham, L.J.2
Smith, S.R.3
Piek, E.4
Saint-Geniez, M.5
-
27
-
-
61949143520
-
NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1
-
Liu H, Kennard S, Lilly B (2009) NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1. Circ Res 104: 466-475.
-
(2009)
Circ Res
, vol.104
, pp. 466-475
-
-
Liu, H.1
Kennard, S.2
Lilly, B.3
-
28
-
-
58649090685
-
Differential gene expression in a coculture model of angiogenesis reveals modulation of select pathways and a role for Notch signaling
-
Lilly B, Kennard S (2009) Differential gene expression in a coculture model of angiogenesis reveals modulation of select pathways and a role for Notch signaling. Physiol Genomics 36: 69-78.
-
(2009)
Physiol Genomics
, vol.36
, pp. 69-78
-
-
Lilly, B.1
Kennard, S.2
-
29
-
-
27144492628
-
Multiple roles for the receptor tyrosine kinase axl in tumor formation
-
Holland SJ, Powell MJ, Franci C, Chan EW, Friera AM, et al. (2005) Multiple roles for the receptor tyrosine kinase axl in tumor formation. Cancer Res 65: 9294-9303.
-
(2005)
Cancer Res
, vol.65
, pp. 9294-9303
-
-
Holland, S.J.1
Powell, M.J.2
Franci, C.3
Chan, E.W.4
Friera, A.M.5
-
30
-
-
1842632667
-
Endothelial cell-cell junctions: Happy together
-
Dejana E (2004) Endothelial cell-cell junctions: happy together. Nat Rev Mol Cell Biol 5: 261-270.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 261-270
-
-
Dejana, E.1
-
31
-
-
0036418093
-
Tightening of endothelial cell contacts: A physiologic response to cocultures with smooth-muscle-like 10T1/2 cells
-
Kurzen H, Manns S, Dandekar G, Schmidt T, Pratzel S, et al. (2002) Tightening of endothelial cell contacts: a physiologic response to cocultures with smooth-muscle-like 10T1/2 cells. J Invest Dermatol 119: 143-153.
-
(2002)
J Invest Dermatol
, vol.119
, pp. 143-153
-
-
Kurzen, H.1
Manns, S.2
Dandekar, G.3
Schmidt, T.4
Pratzel, S.5
-
32
-
-
0027133163
-
Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels
-
Goto F, Goto K, Weindel K, Folkman J (1993) Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels. Lab Invest 69: 508-517.
-
(1993)
Lab Invest
, vol.69
, pp. 508-517
-
-
Goto, F.1
Goto, K.2
Weindel, K.3
Folkman, J.4
-
33
-
-
35248893422
-
What tangled webs they weave: Rho-GTPase control of angiogenesis
-
Bryan BA, D'Amore PA (2007) What tangled webs they weave: Rho-GTPase control of angiogenesis. Cell Mol Life Sci 64: 2053-2065.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 2053-2065
-
-
Bryan, B.A.1
D'Amore, P.A.2
-
34
-
-
34547093441
-
Role of laminin terminal globular domains in basement membrane assembly
-
McKee KK, Harrison D, Capizzi S, Yurchenco PD (2007) Role of laminin terminal globular domains in basement membrane assembly. J Biol Chem 282: 21437-21447.
-
(2007)
J Biol Chem
, vol.282
, pp. 21437-21447
-
-
McKee, K.K.1
Harrison, D.2
Capizzi, S.3
Yurchenco, P.D.4
-
36
-
-
85047694677
-
Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis
-
Ozawa CR, Banfi A, Glazer NL, Thurston G, Springer ML, et al. (2004) Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis. J Clin Invest 113: 516-527.
-
(2004)
J Clin Invest
, vol.113
, pp. 516-527
-
-
Ozawa, C.R.1
Banfi, A.2
Glazer, N.L.3
Thurston, G.4
Springer, M.L.5
-
37
-
-
26944437515
-
PDGFRbeta+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival
-
Song S, Ewald AJ, Stallcup W, Werb Z, Bergers G (2005) PDGFRbeta+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival. Nat Cell Biol 7: 870-879.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 870-879
-
-
Song, S.1
Ewald, A.J.2
Stallcup, W.3
Werb, Z.4
Bergers, G.5
-
38
-
-
0034183694
-
Retroviral delivery of peptide modulators of cellular functions
-
Lorens JB, Bennett MK, Pearsall DM, Throndset WR, Rossi AB, et al. (2000) Retroviral delivery of peptide modulators of cellular functions. Mol Ther 1: 438-447.
-
(2000)
Mol Ther
, vol.1
, pp. 438-447
-
-
Lorens, J.B.1
Bennett, M.K.2
Pearsall, D.M.3
Throndset, W.R.4
Rossi, A.B.5
-
39
-
-
11144267737
-
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein
-
Shaner NC, Campbell RE, Steinbach PA, Giepmans BN, Palmer AE, et al. (2004) Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol 22: 1567-1572.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1567-1572
-
-
Shaner, N.C.1
Campbell, R.E.2
Steinbach, P.A.3
Giepmans, B.N.4
Palmer, A.E.5
-
40
-
-
10744229124
-
Stable, stoichiometric delivery of diverse protein functions
-
Lorens JB, Pearsall DM, Swift SE, Peelle B, Armstrong R, et al. (2004) Stable, stoichiometric delivery of diverse protein functions. J Biochem Biophys Methods 58: 101-110.
-
(2004)
J Biochem Biophys Methods
, vol.58
, pp. 101-110
-
-
Lorens, J.B.1
Pearsall, D.M.2
Swift, S.E.3
Peelle, B.4
Armstrong, R.5
-
41
-
-
0030856731
-
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
Presta LG, Chen H, O'Connor SJ, Chisholm V, Meng YG, et al. (1997) Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 57: 4593-4599.
-
(1997)
Cancer Res
, vol.57
, pp. 4593-4599
-
-
Presta, L.G.1
Chen, H.2
O'Connor, S.J.3
Chisholm, V.4
Meng, Y.G.5
-
42
-
-
0034655182
-
PTK787/ ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
-
Wood JM, Bold G, Buchdunger E, Cozens R, Ferrari S, et al. (2000) PTK787/ ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res 60: 2178-2189.
-
(2000)
Cancer Res
, vol.60
, pp. 2178-2189
-
-
Wood, J.M.1
Bold, G.2
Buchdunger, E.3
Cozens, R.4
Ferrari, S.5
|