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Volumn 133, Issue 8, 2013, Pages 2088-2091

Blocking potassium channels (Kv1.3): A new treatment option for alopecia areata?

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV1.3;

EID: 84880325408     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2013.141     Document Type: Letter
Times cited : (27)

References (14)
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    • Beeton C, Smith BJ, Sabo JK et al. (2008) The D-diastereomer of ShK toxin selectively blocks voltage-gated K\+ channels and inhibits T lymphocyte proliferation. J Biol Chem 283:988-97
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    • Beeton, C.1    Smith, B.J.2    Sabo, J.K.3
  • 4
    • 84862861740 scopus 로고    scopus 로고
    • Ion channels and transporters in lymphocyte function and immunity
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    • (2012) Nat Rev Immunol , vol.12 , pp. 532-547
    • Feske, S.1    Skolnik, E.Y.2    Prakriya, M.3
  • 5
    • 78650287424 scopus 로고    scopus 로고
    • The beneficial effect of blocking Kv1.3 in the psoriasiform SCID mouse model
    • Gilhar A, Bergman R, Assay B et al. (2011) The beneficial effect of blocking Kv1.3 in the psoriasiform SCID mouse model. J Invest Dermatol 131:118-24
    • (2011) J Invest Dermatol , vol.131 , pp. 118-124
    • Gilhar, A.1    Bergman, R.2    Assay, B.3
  • 7
    • 84873703834 scopus 로고    scopus 로고
    • Autoimmune disease induction in a healthy human organ: A humanized mouse model of alopecia areata
    • Gilhar A, Keren A, Shemer A et al. (2013) Autoimmune disease induction in a healthy human organ: a humanized mouse model of alopecia areata. J Invest Dermatol 133: 844-7
    • (2013) J Invest Dermatol , vol.133 , pp. 844-847
    • Gilhar, A.1    Keren, A.2    Shemer, A.3
  • 9
    • 77954223152 scopus 로고    scopus 로고
    • Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
    • Petukhova L, Duvic M, Hordinsky M et al. (2010) Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature 466:113-7
    • (2010) Nature , vol.466 , pp. 113-117
    • Petukhova, L.1    Duvic, M.2    Hordinsky, M.3
  • 10
    • 27544454783 scopus 로고    scopus 로고
    • Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory t cells in autoimmune diseases
    • DOI 10.1124/mol.105.015669
    • Schmitz A, Sankaranarayanan A, Azam P et al. (2005) Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases. Mol Pharmacol 68: 1254-70 (Pubitemid 41539982)
    • (2005) Molecular Pharmacology , vol.68 , Issue.5 , pp. 1254-1270
    • Schmitz, A.1    Sankaranarayanan, A.2    Azam, P.3    Schmidt-Lassen, K.4    Homerick, D.5    Hansel, W.6    Wulff, H.7
  • 11
    • 77952671757 scopus 로고    scopus 로고
    • Contribution of voltage-gated potassium channels to the regulation of apoptosis
    • Szabò I, Zoratti M, Gulbins E (2010) Contribution of voltage-gated potassium channels to the regulation of apoptosis. FEBS Lett 584: 2049-56
    • (2010) FEBS Lett , vol.584 , pp. 2049-2056
    • Szabò, I.1    Zoratti, M.2    Gulbins, E.3
  • 14
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    • Voltagegated potassium channels as therapeutic targets
    • Wulff H, Castle NA, Pardo LA (2009) Voltagegated potassium channels as therapeutic targets. Nat Rev Drug Discovery 8:982-1001
    • (2009) Nat Rev Drug Discovery , vol.8 , pp. 982-1001
    • Wulff, H.1    Castle, N.A.2    Pardo, L.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.