Urotensin II promotes the production of LTC4 in rat aortic adventitial fibroblasts through NF-κB-5-LO pathway by p38 MAPK and ERK activations

Heart and Vessels

Volumn 28, Issue 4, 2013, Pages 514-523

  Dong, Xiao ^a   Ye, Xiaojin ^a   Song, Nana ^a   Zhao, Jing ^a   Di, Beibing ^a   Peng, Fen ^a   Tang, Chaoshu ^b   Ding, Wenhui ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

5 Lipoxygenase; Adventitial fibroblast; Leukotriene; Urotensin II; Vascular inflammation

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUKOTRIENE C4; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PEPTIDE; UROTENSIN II; UROTENSIN RECEPTOR ANTAGONIST;

ANIMAL CELL; AORTA; ARTERY WALL; ARTICLE; BLOOD VESSEL WALL; CARDIOVASCULAR DISEASE; CELL ISOLATION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FATTY ACID SYNTHESIS; FIBROBLAST; GEL MOBILITY SHIFT ASSAY; IMMUNOFLUORESCENCE; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ADVENTITIA; ANIMALS; AORTA; ARACHIDONATE 5-LIPOXYGENASE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; INFLAMMATION MEDIATORS; LEUKOTRIENE C4; MALE; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; TIME FACTORS; UROTENSINS;

EID: 84880319667     PISSN: 09108327     EISSN: 16152573     Source Type: Journal    
DOI: 10.1007/s00380-012-0291-0     Document Type: Article

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