Ligands and signaling of the G-protein-coupled receptor GPR14, expressed in human kidney cells

Cellular Physiology and Biochemistry

Volumn 20, Issue 1-4, 2007, Pages 181-192

  Lehner, Ulrike ^a   Velić, Ana ^a   Schröter, Rita ^a   Schlatter, Eberhard ^a   Sindić, Aleksandra ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Arachidonic acid; CHO cells; GPR14; Guanylin; HEK293 cells; Patch clamp technique; Phospholipase A 2; Uroguanylin; Urotensin II

Indexed keywords

ARACHIDONIC ACID; CALCIUM; CALPHOSTIN C; G PROTEIN COUPLED RECEPTOR; GUANYLATE CYCLASE; GUANYLIN; LIGAND; PHOSPHOLIPASE A2; POTASSIUM CHANNEL; PROTEIN KINASE C; UROTENSIN II;

ARTICLE; CALCIUM CELL LEVEL; CELL STRAIN HEK293; CHO CELL; CONTROLLED STUDY; DEPOLARIZATION; EMBRYO; ENZYME INHIBITION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MICROFLUOROMETRY; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; WHOLE CELL; WILD TYPE;

EID: 34250768137     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000104165     Document Type: Article

References (26)

1. Pearson D, Shively JE, Clark BR, Geschwind II, Barkley M, Nishioka RS, Bern HA: Urotensin II: a somatostatin-like peptide in the caudal neurosecretory system of fishes. Proc Natl Acad Sci USA 1980;77:5021-5024.
2. Douglas SA, Dhanak D, Johns DG: From 'gills to pills': urotensin-II as a regulator of mammalian cardiorenal function. Trends Pharmacol Sci 2004;25:76-85.
3. Matsushita M, Shichiri M, Imai T, Iwashina M, Tanaka H, Takasu N, Hirata Y: Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues. J Hypertens 2001;9:2185-2190.
4. Shenouda A, Douglas SA, Ohlstein EH, Giaid A: Localization of urotensin-II immunoreactivity in normal human kidneys and renal carcinoma. J Histochem Cytochem 2002;50:885-889.
5. Zhang AY, Chen YF, Zhang DX, Yi FX, Qi J, Andrade-Gordon P, de Garavilla L, Li PL. Zou AP: Urotensin II is a nitric oxide-dependent vasodilator and natriuretic peptide in the rat kidney Am J Physiol 2003;285:F792-F798.
6. Ames RS, Sarau HM, Chambers JK, Willette RN, Aiyar NV, Romanic AM, Louden CS, Foley JJ, Sauermelch CF, Coatney RW, Ao Z, Disa J, Holmes SD, Stadel JM, Martin JD, Liu WS, Glover GI, Wilson S, McNulty DE, Ellis CE, Elshourbagy NA, Shabon U, Trill JJ, Hay DW, Ohlstein EH, Bergsma DJ, Douglas SA: Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature 1999;401:282-286.
7. Maguire JJ, Davenport AP: Is urotensin-II the new endothelin? Br J Pharmacol 2002;137:579-588.
8. Liu Q, Pong SS, Zeng Z, Zhang Q, Howard AD, Williams DL Jr, Davidoff M, Wang R, Austin CP, McDonald TP, Bai C, George SR, Evans JF, Caskey CT: Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14. Biochem Biophys Res Commun 1999;266:174-178.
9. Martin S, Adermann K, Forssmann W-G, Kuhn M: Regulated, side-directed secretion of proguanylin from isolated rat colonic mucosa. Endocrinology 1999;140:5022-5029.
10. Greenberg RN, Hill MJ, Crytzer J, Krause WJ, Eber SL, Hamra FK, Forte LR: Comparison of effects of uroguanylin, guanylin, and Escherichia coli heat-stable enterotoxin STa in mouse intestine and kidney: evidence that uroguanylin is an intestinal natriuretic hormone. J Investig Med 1997;45:276-283.
11. Fonteles MC, Greenberg RN, Monteiro HSA, Currie MG, Forte LR: Natriuretic and kaliuretic activities of guanylin and uroguanylin in the isolated perfused rat kidney. Am J Physiol 1998;275:F191-F197.
12. Carrithers SL, Ott CE, Hill MJ, Johnson BR, Cai W, Chang JJ, Shah RG, Sun C, Mann EA, Fonteles MC, Forte LR, Jackson BA, Giannella RA, Greenberg RN: Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor. Kidney Int 2004;65:40-53.
13. Sindic A, Basoglu C, Cerci A, Hirsch JR, Potthast R, Kuhn M, Ghanekar Y, Visweswariah SS, Schlatter E: Guanylin, uroguanylin, and heat-stable enterotoxin activate guanylate cyclase C and/or a pertussis toxin-sensitive G protein in human proximal tubule cells. J Biol Chem 2002;277:17758-17764.
14. Sindic A, Hirsch JR, Velic A, Piechota H, Schlatter E. Guanylin and uroguanylin regulate electrolyte transport in isolated human cortical collecting ducts. Kidney Int 2005;67:1420-7.
15. Sindic A, Velic A, Basoglu C, Hirsch JR, Edemir B, Kuhn M, Schlatter E: Uroguanylin and guanylin regulate transport of mouse cortical collecting duct independent of guanylate cyclase C. Kidney Int 2005; 68:1008-17.
16. Camarda V, Guerrini R, Kostenis E, Rizzi A, Calo G, Hattenberg A, Zucchini M, Salvadori S, Regoli D: A new ligand for the urotensin II receptor. Br J Pharmacol 2002;137:311-314.
17. Ziltener P, Mueller C, Haenig B, Scherz MW, Nayler O: Urotensin II mediates ERK1/2 phosphorylation and proliferation in GPR14-transfected cell lines. J Recept Signal Transduct Res 2002;22:155-168.
18. Greger R, Kunzelmann K: Simultaneous recording of the cell membrane potential and properties of the cell attached membrane of HT29 colon carcinoma and CF-PAC cells. Pflügers Arch 1991;419:209-211.
19. Macica CM, Yang Y, Herbert SC, Wang WH: Arachidonic acid inhibits activity of cloned renal K+ channel, ROMK1. Am J Physiology 1996;271:F588-F594.
20. Herold CL, Behm DJ, Buckley PT, Foley JJ, Wixted WE, Sarau HM, Douglas SA: The neuromedin B receptor antagonist, BIM-23127, is a potent antagonist at human and rat urotensin-II receptors. Br J Pharmacol 2003;139:203-207.
21. Patacchini R, Santicioli P, Giuliani S, Grieco P, Novellino E, Rovero P, Maggi CA:. Urantide: an ultrapotent urotensin II antagonist peptide in the rat aorta. Br J Pharmacol 2003;140:1155-1158.
22. Schlatter E, Fröbe U, Greger R: Ion conductances of isolated cortical collecting duct cells. Pflügers Arch 1992;421:381-387.
23. Schafer JA, Watkins ML, Li L, Herter P, Haxelmans S, Schlatter E: A simplified method for isolation of large numbers of defined nephron segments. Am J Physiol 1997;273:F650-F657.
24. 2+ signalling in rat cortical collecting duct. Cell Calcium 1997;22:269-275.
25. Xu JZ, Hall AE, Peterson LN, Bienkowski MJ, Eessalu TE, Hebert SC: Localization of the ROMK protein on apical membranes of rat kidney nephron segments. Am J Physiol 1997;273:F739-F748.
26. 2 by bromoenol lactone and trifluoromethyl ketones. J Biol Chem 1995;270:445-450.