Effect of antimicrobial peptides from Apis mellifera hemolymph and its optimized version Api88 on biological activities of human monocytes and mast cells

Innate Immunity

Volumn 19, Issue 4, 2013, Pages 355-367

  Keitel, Ulrike ^a   Schilling, Erik ^a   Knappe, Daniel ^a   Al Mekhlafi, Moath ^a   Petersen, Frank ^b   Hoffmann, Ralf ^a   Hauschildt, Sunna ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b Research Center Borstel   (Germany)

Author keywords

Apidaecin; lipopolysaccharide; mast cells; monocytes; phagocytosis; reactive oxygen species; TNF

Indexed keywords

ANTIINFLAMMATORY AGENT; APIDAECIN 1B; CALCIUM ION; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; PEPTIDE DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN API88; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; APIS MELLIFERA; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; ESCHERICHIA COLI; HEMOLYMPH; HUMAN; HUMAN CELL; INNATE IMMUNITY; KLEBSIELLA PNEUMONIAE; MAST CELL; MAST CELL DEGRANULATION; MINIMUM INHIBITORY CONCENTRATION; MONOCYTE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTOSIS; PROTEIN DEGRADATION; PROTEIN STABILITY;

APIDAECIN; LIPOPOLYSACCHARIDE; MAST CELLS; MONOCYTES; PHAGOCYTOSIS; REACTIVE OXYGEN SPECIES; TNF-Α;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BEES; CALCIUM SIGNALING; CELL DEGRANULATION; CELLS, CULTURED; HEMOLYMPH; HUMANS; INSECT PROTEINS; LIPOPOLYSACCHARIDES; MAST CELLS; MONOCYTES; PEPTIDE FRAGMENTS; PROTEIN STABILITY; REACTIVE OXYGEN SPECIES; SEQUENCE HOMOLOGY;

EID: 84880316374     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425912462045     Document Type: Article

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