Macrophage Subset Sensitivity to Endotoxin Tolerisation by Porphyromonas gingivalis

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Foey, Andrew D ^a   Crean, StJohn ^b  

^a UNIVERSITY OF PLYMOUTH   (United Kingdom)

^b UNIVERSITY OF CENTRAL LANCASHIRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; COLECALCIFEROL; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IN VITRO STUDY; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; NONHUMAN; PORPHYROMONAS GINGIVALIS; PROTEIN EXPRESSION;

ANTIGENS, CD14; CELL LINE; HUMANS; IMMUNE TOLERANCE; LIPOPOLYSACCHARIDES; MACROPHAGES; NF-KAPPA B; PORPHYROMONAS GINGIVALIS;

EID: 84880277375     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067955     Document Type: Article

References (40)

1. Socransky SS, Hafferjee AD, Cugini MA, Smith C, Kent RL, (1998) Microbial complexes in subgingival plaque. J. Clin. Periodontol. 25: 134-144.
2. Ximenez-Fyvie LA, Haffajee AD, Socransky SS, (2000) Microbial composition of supra- and subgingival plaque in subjects with adult periodontitis. J. Clin. Periodontol. 27: 722-732.
3. Ezzo P, Cutler CW, (2003) Microorganisms as risk indicators for periodontal disease. Periodontol. 2000. 32: 24-35.
4. Cutler CW, Arnold RR, Schenkein HA, (1993) Inhibition of C3 and IgG proteolysis enhances phagocytosis of Porphyromonas gingivalis. J. Immunol. 151: 7016-7029.
5. Yilmaz O, Watanabe K, Lamont RJ, (2002) Involvement of integrins in fimbriae-mediated binding and invasion by Porphyromonas gingivalis. Cell. Microbiol. 4: 305-314.
6. Jotwani R, Cutler CW, (2004) Fimbriated Porphyromonas gingivalis is more efficient than fimbriae-deficient P. gingivalis in entering human dendritic cells in vitro and induces an inflammatory Th1 effector response. Infect. Immun. 72: 1725-1732.
7. Pulendran B, Kumar P, Cutler CW, Mohamadzadeh M, van Dyke T, et al. (2001) Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo. J. Immunol. 167: 5067-5076.
8. Darveau RP, Pham TT, Lemley K, Reife RA, Bainbridge BW, et al. (2004) Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both Toll-like receptors 2 and 4. Infect. Immun. 72: 5041-5051.
9. Biswas SK, Lopez-Collazo E, (2009) Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol. 30(10): 475-487.
10. Foster SL, Medzhitov R, (2009) Gene-specific control of the TLR-induced inflammatory response. Clin. Immunol. 130: 7-15.
11. Yilmaz O, (2008) The chronicles of Porphyromonas gingivalis: the microbium, the human oral epithelium and their interplay. Microbiol. 154: 2897-2903.
12. Tribble GD, Lamont RJ, (2010) Bacterial invasion of epithelial cells and spreading in periodontal tissue. Periodontol. 2000 52(1): 68-83.
13. Gemmell E, Marshall RI, Seymour GJ, (1997) Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease. Periodontol. 2000 14: 112-143.
14. Okada H, Murakami S, (1998) Cytokine expression in periodontal health and disease. Crit. Rev. Oral Biol. Med. 9: 248-266.
15. Garlet GP, (2010) Destructive and protective roles of cytokines in periodontitis: a re-appraisal from host defence and tissue destruction viewpoints. J. Dent. Res. 89: 1349-1363.
16. Barksby HE, Nile CJ, Jaedicke KM, Taylor JJ, Preshaw PM, (2009) Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipoploysaccharide. Clin. Exp. Immunol. 156: 479-487.
17. Merry R, Belfield L, McArdle P, McLennan A, Crean SJ, et al. (2012) Oral health and pathology: a macrophage account. Brit. J. Oral Maxillofac. Surg. 50: 2-7.
18. Martinez FO, Sica A, Mantovani A, Locati M, (2008) Macrophage activation and polarisation. Front. Biosci. 13: 453-461.
19. Wilson HM, Chettibi S, Jobin C, Walbaum D, Rees AJ, et al. (2005) Inhibition of macrophage nuclear factor-κB leads to a dominant anti-inflammatory phenotype that attenuates glomerular infiltration in vivo. Am. J. Pathol. 167(1): 27-37.
20. Hagemann T, Lawrence T, McNeish I, Charles KA, Kulbe H, et al. (2008) Re-educating tumour associated macrophages by targeting NF-kappaB. J. Exp. Med. 205: 1261-1268.
21. Porta C, Rimoldi M, Raes G, Brys L, Ghezzi P, et al. (2009) Tolerance and M2 (alternative) macrophage polarisation are related processes orchestrated by p50 nuclear factor kappaB. Proc. Natl. Acad. Sci. USA 106: 14978-14983.
22. Tervonen T, Raunio T, Knuuttila M, Karttunen R, (2007) Polymorphisms in the CD14 and IL-6 genes associated with periodontal disease. J. Clin. Periodontol. 34(5): 377-383.
23. Smith PD, Ochsenbauer-Jambor C, Smythies LE, (2005) Intestinal macrophages: unique effector cells of the innate immune system. Immunol. Revs. 206: 149-159.
24. Duncan L, Yoshioka M, Chandad F, Grenier D, (2004) Loss of lipopolysaccharide receptor CD14 from the surface of human macrophage-like cells mediated by Porphyromonas gingivalis outer membrane vesicles. Microb. Pathogen. 36: 319-325.
25. Muthukuru M, Jotwani R, Cutler CW, (2005) Oral mucosal endotoxin tolerance induction in chronic periodontitis. Infect. Immun. 73(2): 687-694.
26. Daigneault M, Preston JA, Marriott HM, Whyte MKB, Dockrell DH, (2010) The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages. PLoS ONE 5: e8668.
27. Hirschfeld M, Ma Y, Weis JH, Vogel SN, Weis JJ, (2000) Repurification of lipopolysaccharide eliminates signaling through both human and murine Toll-like receptor 2. J. Immunol 165: 618-622.
28. Smythies LE, Sellers M, Clements RH, Mosteller-Barnum M, Meng G, et al. (2005) Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity. J. Clin. Invest. 115(1): 66-75.
29. Foey A (2012) Mucosal macrophages: phenotype and functionality in homeostasis and pathology p121-146. In Takahashi R, Kai H (Eds), Handbook of macrophages: life cycle, functions and diseases. Nova Science Publishers Inc., NY, USA.
30. Xing Z, Gauldie J, Cox G, Baumann H, Jordana M, et al. (1998) IL-6 is an anti-inflammatory cytokine required for controlling local or systemic acute inflammatory responses. J. Clin. Invest. 101: 311-320.
31. Heinrich PC, Behrmann I, Haan S, Hermanns HM, Muller-Newen M, et al. (2003) Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem. J. 374: 1-20.
32. Liu Y, Stewart KN, Bishop E, Marek CJ, Kluth DC, et al. (2008) Unique expression of suppressor of cytokine signalling 3 is essential for classical macrophage activation in rodents in vitro and in vivo. J. Immunol. 180: 6270-6278.
33. Foey AD, Parry SL, Williams LW, Feldmann M, Foxwell BMJ, et al. (1998) Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNFα: role of the p38 and p42/44 mitogen activated protein kinases. J. Immunol. 160: 920-928.
34. Greten FR, Arkan MC, Bollrath J, Hsu L-C, Goode J, et al. (2007) NFκB is a negative regulator of IL-1β secretion as revealed by genetic and pharmacological inhibition of IKKβ. Cell 130: 918-931.
35. Sato S, Nomura F, Kawai T, Takeuchi O, Muhlradt PF, et al. (2000) Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR 4-mediated signalling pathways. J. Immunol. 165(12): 7096-7101.
36. Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, et al. (2003) Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signalling pathway components. J. Immunol. 170: 508-519.
37. Kim YG, Park JH, Daignault S, Fukase K, Nunez G, (2008) Cross-tolerisation between Nod1 and Nod2 signalling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages. J. Immunol. 181(6): 4340-4346.
38. O'Neill LAJ, (2008) When signalling pathways collide: positive and negative regulation of Toll-like receptor signal transduction. Immunity 29: 12-20.
39. Robertshaw HJ, Brennan FM, (2005) Release of tumour necrosis factor alpha (TNFalpha) by TNFalpha cleaving enzyme (TACE) in response to septic stimuli in vitro. Brit. J. Anaesthesiol. 94(2): 222-228.
40. Fletcher J, Nair S, Poole S, Henderson B, Wilson M, (1998) Cytokine degradation by biofilms of Porphyromonas gingivalis. Curr. Microbiol. 36(4): 216-219.