Elucidation of the temporal relationship between endothelial-derived NO and EDHF in mesenteric vessels

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 293, Issue 3, 2007, Pages

  Harrington, Louise S ^a,b   Carrier, Martin J ^b   Gallagher, Nicola ^c   Gilroy, Derek ^d   Garland, Chris J ^c   Mitchell, Jane A ^a,e  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c University of Bath   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Arteries; Endothelium derived hyperpolarizing factor; Hyperpolarization; Mediators; Nitric oxide; Vasodilation

Indexed keywords

3,4,5 TRIMETHOXYBENZOIC ACID 8 (DIETHYLAMINO)OCTYL ESTER; ACETYLCHOLINE; APAMIN; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; IMMUNOMODULATING AGENT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; TRAM 34; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOTHELIUM; HYPERPOLARIZATION; MALE; MESENTERIC ARTERY; MESENTERY BLOOD VESSEL; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE; VASODILATATION;

ACETYLCHOLINE; ANIMALS; APAMIN; BIOLOGICAL FACTORS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; MALE; MESENTERIC ARTERIES; MICE; MICE, KNOCKOUT; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PYRAZOLES; RATS; RATS, WISTAR; VASODILATION; VASODILATOR AGENTS;

EID: 34548425667     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00389.2007     Document Type: Article

References (40)

1. Archer SL, Gragasin FS, Wu X, Wang S, McMurtry S, Kim DH, Platonov M, Koshal A, Hashimoto K, Campbell WB, Falck JR, Michelakis ED. Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels. Circulation 107: 769-776, 2003.
2. Beny JL, Brunet PC. Electrophysiological and mechanical effects of substance P and acetylcholine on rabbit aorta. J Physiol 398: 277-289, 1988.
3. Beny JL, Brunet PC. Neither nitric oxide nor nitroglycerin accounts for all the characteristics of endothelially mediated vasodilatation of pig coronary arteries. Blood Vessels 25: 308-311, 1988.
4. Bolotina VM, Najibi S, Palacino JJ, Pagano PJ, Cohen RA. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature 368: 850-853, 1994.
5. Bondarenko A, Sagach V. Na(+)-K(+)-ATPase is involved in the sustained ACh-induced hyperpolarization of endothelial cells from rat aorta. Br J Pharmacol 149: 958-965, 2006.
6. Brandes RP, Schmitz-Winnenthal FH, Feletou M, Godecke A, Huang PL, Vanhoutte PM, Fleming I, Busse R. An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mice. Proc Natl Acad Sci USA 97: 9747-9752, 2000.
7. Brayden JE. Membrane hyperpolarization is a mechanism of endothelium-dependent cerebral vasodilation. Am J Physiol Heart Circ Physiol 259: H668-H673, 1990.
8. Bund SJ. Influence of mode of contraction on the mechanism of acetylcholine-mediated relaxation of coronary arteries from normotensive and spontaneously hypertensive rats. Clin Sci (Lond) 94: 231-238, 1998.
9. Busse R, Edwards G, Feletou M, Fleming I, Vanhoutte PM, Weston AH. EDHF: bringing the concepts together. Trends Pharmacol Sci 23: 374-380, 2002.
10. Campbell WB, Falck JR, Gauthier K. Role of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factor in bovine coronary arteries. Med Sci Monit 7: 578-584, 2001.
11. Chakraborti S, Gurtner GH, Michael JR. Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium. Am J Physiol Lung Cell Mol Physiol 257: L430-L437, 1989.
12. Chauhan S, Rahman A, Nilsson H, Clapp L, MacAllister R, Ahluwalia A. NO contributes to EDHF-like responses in rat small arteries: a role for NO stores. Cardiovasc Res 57: 207-216, 2003.
13. Chauhan SD, Nilsson H, Ahluwalia A, Hobbs AJ. Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor. Proc Natl Acad Sci USA 100: 1426-1431, 2003.
14. Chen G, Suzuki H. Some electrical properties of the endothelium-dependent hyperpolarization recorded from rat arterial smooth muscle cells. J Physiol 410: 91-106, 1989.
15. Chen G, Suzuki H, Weston AH. Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol 95: 1165-1174, 1988.
16. Edwards G, Dora KA, Gardener MJ, Garland CJ, Weston AH. K(+) is an endothelium-derived hyperpolarizing factor in rat arteries. Nature 396: 269-272, 1998.
17. Fisslthaler B, Popp R, Kiss L, Potente M, Harder DR, Fleming I, Busse R. Cytochrome P450 2C is an EDHF synthase in coronary arteries. Nature 401: 493-497, 1999.
18. Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373-376, 1980.
19. Garland JG, McPherson GA. Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery. Br J Pharmacol 105: 429-435, 1992.
20. Gratton JP, Fontana J, O'Connor DS, Garcia-Cardena G, McCabe TJ, Sessa WC. Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1. J Biol Chem 275: 22268-22272, 2000.
21. Huang PL, Huang Z, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, Fishman MC. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377: 239-242, 1995.
22. Ignarro LJ, Byrns RE, Buga GM, Wood KS. Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical. Circ Res 61: 866-879, 1987.
23. Ignarro LJ, Napoli C, Loscalzo J. Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview. Circ Res 90: 21-28, 2002.
24. Komori K, Lorenz RR, Vanhoutte PM. Nitric oxide, ACh, and electrical and mechanical properties of canine arterial smooth muscle. Am J Physiol Heart Circ Physiol 255: H207-H212, 1988.
25. Luckhoff A, Pohl U, Mulsch A, Busse R. Differential role of extra- and intracellular calcium in the release of EDRF and prostacyclin from cultured endothelial cells. Br J Pharmacol 95: 189-196, 1988.
26. Matoba T, Shimokawa H, Nakashima M, Hirakawa Y, Mukai Y, Hirano K, Kanaide H, Takeshita A. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice. J Clin Invest 106: 1521-1530, 2000.
27. Mitchell JA, de Nucci G, Warner TD, Vane JR. Different patterns of release of endothelium-derived relaxing factor and prostacyclin. Br J Pharmacol 105: 485-489, 1992.
28. Mitchell JA, Forstermann U, Warner TD, Pollock JS, Schmidt HH, Heller M, Murad F. Endothelial cells have a particulate enzyme system responsible for EDRF formation: measurement by vascular relaxation. Biochem Biophys Res Commun 176: 1417-1423, 1991.
29. Mitchell JA, Warner TD. COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs. Nat Rev Drug Discov 5: 75-86, 2006.
30. Mitchell JA, Warner TD. Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy. Br J Pharmacol 128: 1121-1132, 1999.
31. Mulvany MJ, Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res 41: 19-26, 1977.
32. Palmer RM, Rees DD, Ashton DS, Moncada S. L-arginine is the physiological precursor for the formation of nitric oxide in endotheliumdependent relaxation. Biochem Biophys Res Commun 153: 1251-1256, 1988.
33. Pollock JS, Forstermann U, Mitchell JA, Warner TD, Schmidt HH, Nakane M, Murad F. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci USA 88: 10480-10484, 1991.
34. Rees DD, Palmer RM, Moncada S. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci USA 86: 3375-3378, 1989.
35. Sessa WC, Harrison JK, Barber CM, Zeng D, Durieux ME, D'Angelo DD, Lynch KR, Peach MJ. Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase. J Biol Chem 267: 15274-15276, 1992.
36. Shimokawa H, Yasutake H, Fujii K, Owada MK, Nakaike R, Fukumoto Y, Takayanagi T, Nagao T, Egashira K, Fujishima M, Takeshita A. The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation. J Cardiovasc Pharmacol 28: 703-711, 1996.
37. Suzuki H, Chen G, Yamamoto Y, Miwa K. Nitroarginine-sensitive and -insensitive components of the endothelium-dependent relaxation in the guinea-pig carotid artery. Jpn J Physiol 42: 335-347, 1992.
38. Tare M, Parkington HC, Coleman HA, Neild TO, Dusting GJ. Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from the endothelium. Nature 346: 69-71, 1990.
39. Taylor HJ, Chaytor AT, Evans WH, Griffith TM. Inhibition of the gap junctional component of endothelium-dependent relaxations in rabbit iliac artery by 18-alpha glycyrrhetinic acid. Br J Pharmacol 125: 1-3, 1998.
40. Wu CC, Chen SJ, Garland CJ. NO and K(ATP) channels underlie endotoxin-induced smooth muscle hyperpolarization in rat mesenteric resistance arteries. Br J Pharmacol 142: 479-484, 2004.