A pilot study of the use of kaolin-impregnated gauze (Combat Gauze) for packing high-grade hepatic injuries in a hypothermic coagulopathic swine model

Journal of Surgical Research

Volumn 183, Issue 2, 2013, Pages 704-709

  Sena, Matthew J ^a,b   Douglas, Geoffrey ^b,c   Gerlach, Travis ^c   Grayson, J Kevin ^b   Pichakron, Kullada O ^b   Zierold, Dustin ^b  

^a KAISER PERMANENTE MEDICAL CENTER   (United States)

^b DAVID GRANT MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Animal model; Coagulopathy; Hemostatic agent; Hypothermia; Kaolin gauze; Liver injury

Indexed keywords

HETASTARCH; KAOLIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD TRANSFUSION; COMBAT GAUZE; COMPARATIVE EFFECTIVENESS; FEMALE; GAUZE DRESSING; HEMODYNAMICS; HISTOLOGY; INFLAMMATION; LAPAROTOMY; LIVER HEMORRHAGE; LIVER INJURY; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; SPLENECTOMY; SWINE; TISSUE NECROSIS;

ANIMAL MODEL; COAGULOPATHY; HEMOSTATIC AGENT; HYPOTHERMIA; KAOLIN GAUZE; LIVER INJURY;

ANIMALS; BANDAGES; BLOOD COAGULATION DISORDERS; DISEASE MODELS, ANIMAL; FEMALE; HEMORRHAGE; HEMOSTATIC TECHNIQUES; HEMOSTATICS; HYPOTHERMIA, INDUCED; INCIDENCE; INFLAMMATION; KAOLIN; LIVER; MALE; NECROSIS; PILOT PROJECTS; SWINE; TREATMENT OUTCOME;

EID: 84880265434     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.02.039     Document Type: Article

References (20)

1. A.E. Pusateri, J.B. Holcomb, and B.S. Kheirabadi Making sense of the preclinical literature on advanced hemostatic products J Trauma 60 2006 674
2. K.R. Ward, M.H. Tiba, and W.H. Holbert Comparison of a new hemostatic agent to current hemostatic agents in a swine model of lethal extremity arterial hemorrhage J Trauma 63 2007 276
3. B.S. Kheirabadi, J.W. Edens, and Terrazas, et al. Comparison of new hemostatic granules/powders with currently deployed hemostatic products in a lethal model of extremity arterial hemorrhage in swine J Trauma 66 2009 316
4. F. Arnaud, K. Teranishi, and T. Okada Comparison of Combat Gauze and TraumaStat in two severe groin injury models J Surg Res 169 2011 92
5. Tactical combat casualty care guidelines, http://www.health.mil/ Libraries/120917-TCCC-Course-Materials/TCCC-Guidelines-120917.pdf; 2012 [accessed 20.01. 13].
6. S.M. Bates, and J.I. Weitz Coagulation assays Circulation 112 2005 53
7. Institute for Laboratory Animal Resources NRC. Guide for the care and use of laboratory animals 1996 National Academy Press Washington, DC
8. J.G. Clay, K. Grayson, and D. Zierold Comparative testing of new hemostatic agents in a swine model of extremity arterial and venous hemorrhage Mil Med 175 2010 280
9. J.L. Sondeen, A.E. Pusateri, and V.G. Coppes Comparison of 10 different hemostatic dressings in an aortic injury J Trauma 54 2003 280
10. A.V. Delgado, B.S. Kheirabadi, and T.M. Fruchterman A novel biologic hemostatic dressing (fibrin patch) reduces blood loss and resuscitation volume and improves survival in hypothermic, coagulopathic swine with grade V liver injury J Trauma 64 2008 75
11. S.D. Cho, J.B. Holcomb, and B.H. Tieu Reproducibility of an animal model simulating complex combat-related injury in a multiple-institution format Shock 31 2009 87
12. J.G. Clay, D. Zierold, K. Grayson, and F.D. Battistella Application of a dextran polymer hemostatic dressing (Bloxx) improves survival in a swine model of lethal liver injury J Surg Res 155 2009 89
13. M.A. Pett Nonparametric statistics for healthcare research: statistics for small sample sizes and unusual distributions 1997 Sage Publications Thousand Oaks, CA
14. E.D. Cox, M.A. Schreiber, and J. McManus New hemostatic agents in the combat setting Transfusion 49 Suppl 5 2009 248S
15. T. Gerlach, K. Grayson, and K. Pichakron Preliminary study of the effects of smectite granules (WoundStat) on vascular repair and wound healing in a swine survival model J Trauma 69 2010 1203
16. B.S. Kheirabadi, J.E. Mace, and I.B. Terrazas Safety evaluation of new hemostatic agents, smectite granules, and kaolin-coated gauze in a vascular injury wound model in swine J Trauma 68 2010 269
17. J. Margolis The kaolin clotting time; a rapid one-stage method for diagnosis of coagulation defects J Clin Pathol 11 1958 406
18. F. Arnaud, D. Parreño-Sadalan, and T. Tomori Comparison of 10 hemostatic dressings in a groin transection model in swine J Trauma 67 2009 848
19. B.S. Kheirabadi, J.E. Mace, and I.B. Terrazas Clot-inducing minerals versus plasma protein dressing for topical treatment of external bleeding in the presence of coagulopathy J Trauma 69 2010 1062
20. G.P. De Castro, M.J. MacPhee, and I.R. Driscoll New hemostatic dressing (FAST) reduces blood loss and improves survival in a grade V liver injury model in noncoagulopathic swine J Trauma 70 2011 1408