Engineering stem cells for future medicine

IEEE Transactions on Biomedical Engineering

Volumn 60, Issue 3, 2013, Pages 727-734

  Ricotti, Leonardo ^a   Menciassi, Arianna ^a  

^a SCUOLA SUPERIORE SANT ANNA   (Italy)

Author keywords

Engineered materials; Mechatronic integrated biodevices; Regenerative medicine; Stem cell differentiation; Tissue engineering

Indexed keywords

BIO-DEVICES; CLINICAL APPLICATION; ENABLING TECHNOLOGIES; ENGINEERED MATERIALS; PHYSICAL STIMULATIONS; REGENERATIVE MEDICINE; STEM CELL DIFFERENTIATION; THERAPEUTIC DELIVERY;

ROBOTICS; TISSUE ENGINEERING;

STEM CELLS;

NANOFILM; NANOPARTICLE;

ARTICLE; BIODEGRADABILITY; CELL ACTIVITY; CELL ADHESION; CELL DIFFERENTIATION; CELL ENGINEERING; CELL FATE; CELL FUNCTION; CELL INTERACTION; CELL LINEAGE; CELL MATURATION; DAUGHTER CELL; DNA METHYLATION; DNA SEQUENCE; ELECTRIC CONDUCTIVITY; ELECTRIC CURRENT; ELECTRIC FIELD; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; EXTRACELLULAR MATRIX; GENETIC REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; MAGNETIC FIELD; MESENCHYMAL STEM CELL; MICROELECTRODE; MICROENVIRONMENT; MULTIPOTENT STEM CELL; NUCLEAR MAGNETIC RESONANCE IMAGING; PARACRINE SIGNALING; PLURIPOTENT STEM CELL; REGENERATIVE MEDICINE; ROBOTICS; STEM CELL; STEM CELL CULTURE; STEM CELL NICHE; STIMULATION; TARGET ORGAN; TISSUE DIFFERENTIATION; TOTIPOTENT STEM CELL;

ANIMALS; BIOMEDICAL ENGINEERING; CELL DIFFERENTIATION; HUMANS; NANOMEDICINE; REGENERATIVE MEDICINE; ROBOTICS; STEM CELLS; TISSUE ENGINEERING;

EID: 84880233937     PISSN: 00189294     EISSN: 15582531     Source Type: Journal    
DOI: 10.1109/TBME.2013.2244093     Document Type: Article

References (57)

1. J. A. Baddour, K. Sousounis, and P. A. Tsonis, "Organ repair and regeneration: An overview," Birth Defects Res. C Embryo Today, vol. 96, pp. 1-29, Mar. 2012.
2. F. M. Watt and B. L. M. Hogan, "Out of eden: Stem cells and their niches," Science, vol. 287, pp. 1427-1430, Feb. 2000.
3. M. A. Cross and T. Enver, "The lineage commitment of haemopoietic progenitor cells," Curr. Opin. Gen. Dev., vol. 7, no. 5, pp. 609-613, Oct. 1997. (Pubitemid 27491424)
4. H. W. Lee, M. A. Blasco, G. J. Gottlieb, J. W. Horner II, C. W. Greider, and R. A. DePinho, "Essential role of mouse telomerase in highly proliferative organs," Nature, vol. 392, pp. 569-574, Apr. 1998.
5. P. J. Quesenberry and P. S. Becker, "Stem cell homing: Rolling, crawling and nesting," Proc. Nat. Acad. Sci., vol. 95, no. 26, pp. 15155-15157, Dec. 1998.
6. R. Mazhari and J. M. Hare, "Mechanisms of action of mesenchymal stem cells in cardiac repair: Potential influences of the cardiac stem cell niche," Nat. Clin. Pract. Cardiovasc. Med., vol. 1, pp. S21-S26, Feb. 2007. (Pubitemid 46151902)
7. M. Gnecchi, Z. Zhang, A. Ni, and V. J. Dzau, "Paracrine mechanisms in adult stem cell signaling and therapy," Circ. Res., vol. 103, pp. 1204-1219, Nov. 2008.
8. J. M. Nygren, S. Jovinge, M. Breitbach, P. Säwén, W. Röll, J. Hescheler, J. Taneera, B. F. Fleischmann, and S. E. W. Jacobsen, "Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation," Nature Med., vol. 10, pp. 494-501, Apr. 2004. (Pubitemid 38667908)
9. A. De Angelis, E. Piegari, D. Cappetta, L. Marino, A. Filippelli, L. Berrino, J. Ferreira-Martins, H. Zheng, T. Hosoda, M. Rota, K. Urbanek, J. Kajstura, A. Leri, F. Rossi, and P. Anversa, "Anthracycline cardiomyophaty is mediated by depletion of the cardiac stem cell pool and is rescued by restoration of progenitor cell function," Circulation, vol. 121, pp. 276-292, Dec. 2009.
10. A. B. Mathiasen, E. Jørgensen, A. A. Qayyum, M. Haack-Sørensen, A. Ekblond, and J. Kastrup, "Rationale and design of the first randomized, double-blind, placebo-controlled trial of intramyocardial injection of autologous bone-marrowderived mesenchymal stromal cells in chronic ischemic heart failure (MSC-HF trial)," Am. Heart J., vol. 164, pp. 285-291, Sep. 2012.
11. M. Kramer, P. Heussner, P. Y. Herzberg, H. Andree, I. Hilgendorf, M. Leithaeuser, C. Junghanss, M. Freund, and D. Wolff, "Validation of the grip test and human activity profile for evaluation of physical performance during the intermediate phase after allogeneic hematopoietic stem cell transplantation," Support Care Cancer, Nov. 2012, doi:10.1007/s00520-012- 1634-1.
12. J. Leventhal, M. Abecassis, J. Miller, L. Gallon, R. Herzig, D. J. Tollerud, B. King, and S. T. Ildstad, "A Phase 2 clinical trial of donor specific tolerance induction in recipients of HLA Disparate living donor kidney allografts by donor stem cell infusion," Transplantation, vol. 94, p. 148, Nov. 2012.
13. C. Sheridan, "Cardiac stem cell therapies inch toward clinical litmus test," Nature Biotech., vol. 31, pp. 5-6, Jan. 2013.
14. S. Kern, H. Eichler, J. Stoeve, H. Klüter, and K. Bieback, "Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue," Stem Cells, vol. 24, pp. 1294-1301, Jan. 2006. (Pubitemid 44464698)
15. K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka, "Induction of pluripotent stem cells from adult human fibroblasts by defined factors," Cell, vol. 131, pp. 861-872, Nov. 2007. (Pubitemid 350138099)
16. J. Zhang, G. F. Wilson, A. G. Soerens, C. H. Koonce, J. Yu, S. P. Palecek, J. A. Thomson, and T. J. Kamp, "Functional cardiomyocytes derived from human induced pluripotent stem cells," Circ Res., vol. 104, no. 4, pp. e30-e41, Feb. 2009.
17. Z. Song, J. Cai, Y. Lui, D. Zhao, J. Yong, S. Dao, X. Song, Y. Guo, Y. Zhao, H. Qin, X. Yin, C. Wu, J. Che, S. Lu, M. Ding, and H. Deng, "Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells," Cell Res., vol. 19, no. 11, pp. 1233-1242, Nov. 2009.
18. Z. Alipio, W. Liao, E. J. Roemer, M. Waner, L. M. Fink, D. C. Ward, and Y. Ma, "Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic β-like cells," Proc Nat. Acad. Sci., vol. 107, no. 30, pp. 13426-13431, Jul. 2010.
19. A. Swistowski, J. Peng, Q. Liu, P. Mali, M. S. Rao, L. Cheng, and X. Zeng, "Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions," Stem Cells, vol. 28, pp. 1893-1904, Oct. 2010.
20. M. Votteler, P. J. Kluger, H. Walles, and K. Schenke-Layland, "Stem cell microenvironments - Unveiling the secrets of how stem cell fate is defined," Macromol. Biosci., vol. 10, pp. 1302-1305, Nov. 2010.
21. I. H. Park, N. Arora, H. Huo, N. Maherali, T. Ahfeldt, A. Shimamura, M. W. Lensch, C. Cowan, K. Hochedlinger, and G. Q. Daley, "Disease-specific induced pluripotent stem cells," Cell, vol. 134, pp. 877-886, Sep. 2008.
22. K. Kim, A. Doi, B. Wen, K. Ng, R. Zhao, P. Cahan, J. Kim, M. J. Aryee, H. Ji, L. I. R. Ehrlich, A. Yabuuchi, A. Takeuchi, K. C. Cunniff, H. Hongguang, S. Mckinney-Freeman, O. Naveiras, T. J. Yoon, R. A. Irizarry, N. Jung, J. Seita, J. Hanna, P. Murakami, R. Jaenisch, R. Weissleder, S. H. Orkin, I. L. Weissman, A. P. Feinberg, and G. Q. Daley, "Epigenetic memory in induced pluripotent stem cells," Nature, vol. 467, pp. 285-290, Sep. 2010.
23. D. E. Discher, D. J. Mooney, and P. W. Zandstra, "Growth factors, matrices, and forces combine and control stem cells," Science, vol. 324, pp. 1673-1677, Jun. 2009.
24. B. G. Chung, L. A. Flanagan, S. W. Rhee, P. H. Schwartz, A. P. Lee, E. S. Monuki, and N. L. Jeon, "Human neural stem cell growth and differentiation in a gradient-generating microfluidic device," Lab Chip., vol. 5, pp. 401-406, Mar. 2005.
25. R. L. Judson, J. E. Babiarz, M. Venere, and R. Blelloch, "Embryonic stem cell-specific microRNAs promote induced pluripotency," Nature Biotechnol., vol. 27, no. 5, pp. 459-461, May 2009.
26. M. Baker, "Why hES cells make teratomas," Nature Rep. Stem Cells, Mar. 2009, doi: 10.1038/stemcells.2009.36.
27. J. Fu, Y. K. Wang, M. T. Yang, R. A. Desai, X. Yu, Z. Lin, and C. S. Chen, "Mechanical regulation of cell function with geometrically modulated elastomeric substrates," Nature Methods, vol. 7, no. 9, pp. 733-736, Sep. 2010.
28. A. Khademhosseini and R. Langer, "Microengineered hydrogels for tissue engineering," Biomaterials., vol. 28, pp. 5087-5092, Dec. 2007.
29. T. Boudou, T. Crouzier, K. F. Ren, G. Blin, and C. Picart, "Multiple functionalities of polyelectrolyte multilayer films: New biomedical applications," Adv. Mater., vol. 22, pp. 441-467, Jan. 2010.
30. G. Ciofani, L. Ricotti, A. Menciassi, and V. Mattoli, "Preparation, characterization and in vitro testing of poly(lactic-co-glycolic) acid/barium titanate nanoparticle composites for enhanced cellular proliferation," Biomed. Microdev., vol. 13, no. 2, pp. 255-266, Apr. 2011.
31. S. Cagnin, E. Cimetta, C. Guiducci, P. Martini, and G. Lanfranchi, "Overview of micro- and nano-technology tools for stem cell applications: Micropatterned and microelectronic devices," Sensors, vol. 12, pp. 15947-15982, Nov. 2012.
32. E. Cimetta, M. Flaibani, M. Mella, E. Serena, L. Boldrin, P. De Coppi, and N. Elvassore, "Enhancement of viability of muscle precursor cells on 3-D scaffold in a perfusion bioreactor," Int. J. Artif. Organs., vol. 30, pp. 415-428, May 2007. (Pubitemid 47072698)
33. N. Wang, G. Adams, L. Buttery, F. H. Falcone, and S. Stolnik, "Alginate encapsulation technology supports embryonic stem cells differentiation into insulin-producing cells," J. Biotechnol., vol. 144, pp. 304-312, Dec. 2009.
34. G. J. Delcroix, P. C. Schiller, J. P. Benoit, and C. N. Montero-Menei, "Adult cell therapy for brain neuronal damages and the role of tissue engineering," Biomaterials, vol. 31, pp. 2105-2120, Mar. 2010.
35. A. Nieponice, L. Soletti, J. Guan, B. M. Deasy, J. Huard, W. R. Wagner, and D. A. Vorp, "Development of a tissue-engineered vascular graft combining a biodegradable scaffold, muscle-deriving stem cells and a rotational vacuum seeding technique," Biomaterials, vol. 29, pp. 825-833, Mar. 2008. (Pubitemid 350266044)
36. G. Ciofani, L. Ricotti, S. Danti, S. Moscato, C. Nesti, D. D'Alessandro, D. Dinucci, F. Chiellini, A. Pietrabissa, M. Pietrini, and A. Menciassi, "Investigation of interactions between poly-L-lysine-coated boron nitride nanotubes and C2C12 cells: Up-take, cytocompatibility, and differentiation, " Int. J. Nanomed., vol. 5, pp. 285-298, Apr. 2010.
37. G. Ciofani, S. Danti, D. D'Alessandro, L. Ricotti, S. Moscato, G. Bertoni, A. Falqui, S. Berrettini, M. Petrini, V. Mattoli, and A. Menciassi, "Enhancement of neurite outgrowth in neuronal-like cells following boron nitride nanotube-mediated stimulation," ACS Nano, vol. 4, no. 10, pp. 6267-6277, Oct. 2010.
38. J. El-Ali, P. K. Sorger, and K. F. Jensen, "Cells on chips," Nature, vol. 442, pp. 403-411, Jul. 2006.
39. B. C. Wheeler, "Designing neural networks in culture," Proc. IEEE, vol. 98, no. 3, pp. 398-406, Mar. 2010.
40. D. H. Kim, N. Lu, R. Ma, Y. S. Kim, R. H. Kim, S. Wang, J. Wu, S. M. Won, H. Tao, A. Islam, K. J. Yu, T.-i. Kim, R. Chowdhury, M. Ying, L. Xu, M. Li, H.-J. Chung, H. Keum, M. McCormick, P. Liu, Y.-W. Zhang, F. G. Omenetto, Y. Huang, T. Coleman, and J. A. Rogers, "Epidermal electronics," Science, vol. 333, no. 6044, pp. 838-843, Aug. 2011.
41. F. Greco, T. Fujie, S. Taccola, L. Ricotti, A. Menciassi, and V. Mattoli, "Micro and nanowrinkled conductive polymer surfaces on shape-memory polymer substrates: Tuning of surface microfeatures towards smart biointerfaces," MRS Proc., vol. 1411, Jan. 2012, doi: 10.1557/opl.2012.474.
42. F. Greco, T. Fujie, L. Ricotti, S. Taccola, B. Mazzolai, and V. Mattoli, "Microwrinkled conducting polymer interface for anisotropic multicellular alignment," Appl. Mat. Interf., doi: 10.1021/am301908w, Dec. 2012.
43. Y. Zhao, J. Zhou, W. Dai, Y. Zheng, and H. Wu, "A convenient platform of tunable microlens arrays for the study of cellular responses to mechanical strains," J. Micromech. Microeng., vol. 21, no. 5, p. 054017, May 2011, doi:10.1088/0960-1317/21/5/054017.
44. X. R. Zheng and X. Zhang, "Microsystems for cellular force measurement: A review," J Micromech. Microeng., vol. 21, no. 5, p. 054003, May 2011, doi: 10.1088/0960-1317/21/5/054003.
45. J. Wegener, C. R. Keese, and I. Giaver, "Electric cell-substrate impedance sensing (ECIS) as a noninvasive means to monitor the kinetics of cell spreading to artificial substrates," Exp. Cell Res., vol. 259, pp. 158-166, Aug. 2000.
46. T. Sun and H. Morgan, "Single-cell microfluidic impedance cytometry: A review," Microfluid. Nanofluid., vol. 8, no. 4, pp. 423-443, Apr. 2010.
47. P. Linderholm, L. Marescot, H. L. Meng, and P. Renaud, "Cell culture imaging using microimpedance tomography," IEEE Trans. Biomed. Eng., vol. 55, no. 1, pp. 138-146, Jan. 2008. (Pubitemid 350308431)
48. M. Thein, F. Asphahani, A. Cheng, R. Buckmaster, M. Zhang, and J. Xu, "Response characteristics of single-cell impedance sensors employed with surface-modified microelectrodes," Biosens. Bioelectron., vol. 25, no. 8, pp. 1963-1969, Apr. 2010.
49. J. Guck, R. Ananthakrishnan, H. Mahmood, T. J. Moon, C. C. Cunningham, and J. Käs, "The optical stretcher: A novel laser tool to micromanipulate cells," Biophys. J., vol. 81, no. 2, pp. 767-784, Aug. 2001. (Pubitemid 32721451)
50. J. Galle, G. Aust, G. Schaller, T. Beyer, and D. Drasdo, "Individual cell-based models of the spatial-temporal organization of multicellular systems - Achievements and limitations," Cytometry A, vol. 69 A, pp. 704-710, Jun. 2006.
51. R. M. H. Merks and J. A. Glazier, "A cell-centered approach to developmental biology," Phys. A: Stat. Mech. Appl., vol. 352, no. 1, pp. 113-130, Jul. 2005.
52. J. Shim, A. Grosberg, J. C. Nawroth, K. K. Parker, and K. Bertoldi, "Modeling of cardiac muscle thin films: Pre-stretch, passive and active behavior," J. Biomech., vol. 45, no. 5, pp. 832-841, Mar. 2012.
53. L. Ricotti, S. Taccola, V. Pensabene, V. Mattoli, T. Fujie, S. Takeoka, A. Menciassi, and P. Dario, "Adhesion and proliferation of skeletal muscle cells on single layer poly(lactic acid) ultra-thin films," Biomed. Microdev., vol. 12, pp. 809-819, Jun. 2010.
54. V. Pensabene, S. Taccola, L. Ricotti, G. Ciofani, A. Menciassi, F. Perut, M. Salerno, P. Dario, and N. Baldini, "Flexible polymeric ultrathin film for mesenchymal stem cell differentiation," Acta Biomater., vol. 7, no. 7, pp. 2883-2891, Jul. 2011.
55. S. Taccola, A. Desii, V. Pensabene, T. Fujie, A. Saito, S. Takeoka, P. Dario, A. Menciassi, and V. Mattoli, "Free-standing poly(L-lactic acid) nanofilms loaded with superparamagnetic nanoparticles," Langmuir, vol. 27, no. 9, pp. 5589-5595, Apr. 2011.
56. R. Seip, T. C. Chien, C. S. Hall, B. I. Raju, A. Ghanem, and K. Tiemann, "Targeted ultrasound-mediated delivery of nanoparticles: On the development of a new HIFU-based therapy and imaging device," IEEE Trans. Biomed. Eng., vol. 57, no. 1, pp. 61-70, Jan. 2010.
57. N. N. Kachouie and P. W. Fieguth, "Extended-Hungarian-JPDA: Exact single-frame stem cell tracking," IEEE Trans. Biomed. Eng., vol. 54, no. 11, pp. 2011-2019, Nov. 2007.