Preparation, characterization and in vitro testing of poly (lactic-co-glycolic) acid/barium titanate nanoparticle composites for enhanced cellular proliferation

Biomedical Microdevices

Volumn 13, Issue 2, 2011, Pages 255-266

  Ciofani, Gianni ^a   Ricotti, Leonardo ^a   Menciassi, Arianna ^a   Mattoli, Virgilio ^a  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

Barium titanate nanoparticles; Muscle cells; Poly(lactic co glycolic) acid; Polymer ceramic composites; Tissue engineering

Indexed keywords

3-D CULTURE SYSTEM; BARIUM TITANATE NANOPARTICLES; CELL LINES; CELL-BASED; CELLULAR PROLIFERATIONS; IN-VITRO; MUSCLE CELLS; POLY LACTIC-CO-GLYCOLIC ACID; POLYMER/CERAMIC COMPOSITES; POROUS SCAFFOLD;

BARIUM; CELL CULTURE; CELL PROLIFERATION; MATERIALS TESTING; MUSCLE; NANOPARTICLES; TISSUE ENGINEERING;

BARIUM TITANATE;

BARIUM; NANOPARTICLE; POLYGLACTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOCOMPATIBILITY; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL VIABILITY; COMPOSITE MATERIAL; CONTROLLED STUDY; CYTOTOXICITY; DNA CONTENT; IMAGE ANALYSIS; IN VITRO STUDY; MECHANICS; MUSCLE CELL; NONHUMAN; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; TENSILE STRENGTH; TISSUE ENGINEERING; X RAY DIFFRACTION; YOUNG MODULUS;

ANIMALS; BARIUM COMPOUNDS; CELL LINE; CELL PROLIFERATION; GUIDED TISSUE REGENERATION; LACTIC ACID; NANOCOMPOSITES; NANOPARTICLES; POLYGLYCOLIC ACID; POROSITY; RATS; SURFACE PROPERTIES; TENSILE STRENGTH; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TITANIUM;

EID: 79958142070     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-010-9490-6     Document Type: Article

References (38)

1. F.R. Baxter, C.R. Bowen, I.G. Turner, A.C.E. Dent, Electrically active bioceramics: a review of interfacial responses. Ann. Biomed. Eng. 38, 2079 (2010)
2. 3. J. Eur. Ceram. Soc. 20, 1997 (2000)
3. F. Brandl, F. Sommer, A. Goepferich, Rational design of hydrogels for tissue engineering: impact of physical factors on cell behavior. Biomaterials 28, 134 (2007)
4. W.D. Callister, Materials Science and Engineering: An Introduction, 6th edn. (John Wiley & Sons, Inc, 2003), pp. 113-152
5. F. Causa, P.A. Netti, L. Ambrosio, G. Ciapetti, N. Baldini, S. Pagani, D. Martini, A. Giunti, Poly-e-caprolactone/hydroxyapatite composites for bone regeneration: in vitro characterization and human osteoblast response. J. Biomed. Mater. Res. A 76, 151 (2006)
6. P. Cerrai, G.D. Guerra, M. Tricoli, A. Krajewski, S. Guicciardi, A. Ravaglioli, S. Maltinti, G. Masetti, New composites of hydroxyapatite and bioresorbable macromolecular material. J. Mater. Sci. Mater. Med. 10, 283 (1999)
7. S.Y. Chung, I.D. Kim, S.J.L. Kang, Strong nonlinear current-voltage behaviour in perovskite-derivative calcium copper titanate. Nat. Mater. 3, 774 (2004)
8. G. Ciofani, S. Danti, S. Moscato, L. Albertazzi, D. D'Alessandro, D. Dinucci, F. Chiellini, M. Petrini, A. Menciassi, Preparation of stable dispersion of barium titanate nanoparticles: potential applications in biomedicine. Colloid Surf. B 76, 535 (2010a)
9. G. Ciofani, S. Danti, D. D'Alessandro, S. Moscato, M. Petrini, A. Menciassi, Barium titanate nanoparticles: highly cytocompatible dispersions in glycol-chitosan and doxorubicin complexes for cancer therapy. Nanoscale Res. Lett. 5, 1093 (2010b)
10. G. Ciofani, S. Danti, D. D'Alessandro, L. Ricotti, S. Moscato, G. Bertoni, A. Falqui, S. Berrettini, M. Petrini, V. Mattoli, A. Menciassi, On line Enhancement of neurite outgrowth in neuronal-like cells following boron nitride nanotube-mediated stimulation. ACS Nano, doi:10.1021/nn101985a
11. P.Y.W. Dankars, M.C. Harmsen, L.A. Brouwer, M.J.A. Van Luyn, E. W. Meijer, A modular and supramolecular approach to bioactive scaffolds for tissue engineering. Nat. Mater. 4, 568 (2005)
12. S.L. Edwards, J.S. Church, J.A. Werkmeister, J.A. Ramshaw, Tubular micro-scale multiwalled carbon nanotube-based scaffolds for tissue engineering. Biomaterials 30, 1725 (2009)
13. J. Gao, B. Xu, Applications of nanomaterials inside cells. Nano Today 4, 37 (2009)
14. B.S. Harrison, A. Atala, Carbon nanotube applications for tissue engineering. Biomaterials 28, 344 (2007)
15. D. Hennings, C. Metzmacher, B. Schreinemacher, Defect chemistry and microstructure of hydrothermal barium titanate. J. Am. Ceram. Soc. 84, 179 (2001)
16. C.L. Hsieh, R. Grange, Y. Pu, D. Psaltis, Bioconjugation of barium titanate nanocrystals with immunoglobulin G antibody for second harmonic radiation imaging probes. Biomaterials 31, 2272 (2010)
17. N.F. Huang, S. Patel, R.G. Thakar, J. Wu, B.S. Hsiao, B. Chu, R.J. Lee, S. Li, Myotube assembly on nanofibrous and micropatterned polymers. Nano Lett. 6, 537 (2006)
18. B.W. Kimes, B.L. Brandt, Properties of a clonal muscle cell line from rat heart. Exp. Cell Res. 98, 367 (1976)
19. D. Lahiri, F. Rouzaud, S. Namin, A.K. Keshri, J.J. Valdés, L. Kos, N. Tsoukias, A. Agarwal, Carbon nanotube reinforced polylactide-caprolactone copolymer: mechanical strengthening and interaction with human osteoblasts in vitro. ACS Appl. Mater. Inter. 1, 2470 (2009)
20. H.J. Lee, O.J. Yoon, D.H. Kim, Y.M. Jang, H.W. Kim, W.B. Lee, N.E. Lee, S.S. Kim, Neurite outgrowth on nanocomposite scaffolds synthesized from PLGA and carboxylated carbon nanotubes. Adv. Eng. Mater. 11, 261 (2009)
21. H.R. Lin, C.J. Kuo, C.Y. Yang, S.Y. Shaw, Y.J. Wu, Preparation of macroporous biodegradable PLGA scaffolds for cell attachment with the use of mixed salts as porogen additives. J. Biomed. Mater. Res. B 63, 271 (2002)
22. H. Liu, E.B. Slamovich, T.J. Webster, Increased osteoblast functions among nanophase titania/poly(lactide-co-glycolide) composites of the highest nanometer surface roughness. J. Biomed. Mater. Res. A 78, 798 (2006)
23. S. Loher, V. Reboul, T.J. Brunner, M. Simonet, C. Dora, P. Neuenschwander, W.J. Stark, Improved degradation and bioactivity of amorphous aerosol derived tricalcium phosphate nanoparticles in poly(lactide-co-glycolide) . Nanotechnology 17, 2054 (2006)
24. A.M. Martins, Q.P. Pham, P.B. Malafaya, R.M. Raphael, F.K. Kasper, R.L. Reis, A.G. Mikos, Natural stimulus responsive scaffolds/cells for bone tissue engineering: influence of lysozyme upon scaffold degradation and osteogenic differentiation of cultured marrow stromal cells induced by CaP coatings. Tissue Eng. A 15, 1953 (2009)
25. V.V. Meretoja, A.O. Helminen, J.J. Korventausta, V. Haapa-aho, J.V. Seppälä, T.O. Närhi, Crosslinked poly(epsilon-caprolactone/D, L-lactide)/bioactive glass composite scaffolds for bone tissue engineering. J. Biomed. Mater. Res. A 77, 261 (2006)
26. A.G. Mikos, A.J. Thorsen, L.A. Czerwonka, Y. Bao, R. Langer, D.N. Winslow, J.P. Vacanti, Preparation and characterization of poly (L-lactic acid) foams. Polymer 35, 1068 (1994)
27. T. Ranne, T. Tirri, A.Y. Urpo, T.O. Narhi, V.J.O. Laine, J. Rich, J. Seppala, A. Aho, In vivo behavior of poly(e-caprolactone-co-D, L-lactide)/ bioactive glass composites in rat subcutaneous tissue. J. Bioac. Compat. Pol. 22, 249 (2007)
28. L. Richert, F. Vetrone, J.H. Yi, S.F. Zalzal, J.D. Wuest, F. Rosei, A. Nanci, Surface nanopatterning to control cell growth. Adv. Mater. 20, 1488 (2008)
29. F. Rosso, G. Marino, A. Giordano, M. Barbarisi, D. Parmeggiani, A. Barbarisi, Smart materials as scaffolds for tissue engineering. J. Cell. Physiol. 203, 465 (2005)
30. J. Russias, E. Saiz, R.K. Nalla, K. Gryn, R.O. Ritchie, A.P. Tomsia, Fabrication and mechanical properties of PLA/HA composites: a study of in vitro degradation. Mater. Sci. Eng. C 26, 1289 (2006)
31. H. Shin, S. Jo, A.G. Mikos, Biomimetic materials for tissue engineering. Biomaterials 24, 4353 (2003)
32. V.L. Singer, L.J. Jones, S.T. Yue, R.P. Haugland, Characterization of PicoGreen reagent and development of a fluorescence-based solution assay for double-stranded DNA quantitation. Anal. Biochem. 249, 228 (1997)
33. J. Tao, J. Ma, Y. Wang, X. Zhu, J. Liu, X. Jiang, B. Lin, Y. Ren, Synthesis of barium titanate nanoparticles via a novel electrochemical route. Mater. Res. Bull. 43, 639 (2008)
34. H.T. Wang, H. Palmer, R.J. Linhardt, D.R. Flanagan, E. Schmitt, Degradation of poly(ester) microspheres. Biomaterials 11, 679 (1990)
35. Y.J. Wang, X.T. Shi, L. Ren, Y.C. Yao, F. Zhang, D.A. Wang, Poly (lactide-co-glycolide)/titania composite microsphere-sintered scaffolds for bone tissue engineering applications. J. Biomed. Mater. Res. B 93, 84 (2010)
36. F. Yang, W. Cui, Z. Xiong, L. Liu, J. Bei, S. Wang, Poly(l,l-lactide- coglycolide)/tricalcium phosphate composite scaffold and its various changes during degradation in vitro. Polym. Degrad. Stabil. 91, 3065 (2006)
37. D.H. Yoon, B.I. Lee, P. Badheka, X.Y. Wang, Barium ion leaching from barium titanate powder in water. J. Mater. Sci. Mat. Electron. 14, 165 (2003)
38. D.M. Yunos, O. Bretcanu, A.R. Boccaccini, Polymer-bioceramic composites for tissue engineering scaffolds. J. Mater. Sci. 43, 4433 (2008)