Alginate encapsulation technology supports embryonic stem cells differentiation into insulin-producing cells

Journal of Biotechnology

Volumn 144, Issue 4, 2009, Pages 304-312

  Wang, Nan ^a   Adams, Gary ^a   Buttery, Lee ^b   Falcone, Franco H ^b   Stolnik, Snow ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Alginate encapsulation technology; Embryonic stem cells; Insulin producing cells; Pancreatic differentiation

Indexed keywords

ALGINATE BEADS; ALGINATE ENCAPSULATION; ALGINATE MATRIX; CELL DENSITY; CELL VIABILITY; DIFFERENTIATED CELLS; EMBRYONIC STEM CELLS; ES CELLS; IMMUNOSTAINING; MATRIX; POTENTIAL BENEFITS; PRODUCTION CAPABILITIES; RT-PCR ANALYSIS;

AGGLOMERATION; ALGINATE; CELL CULTURE; COMPUTER CRIME; GLUCOSE; INSULIN; TECHNOLOGY; TWO DIMENSIONAL;

CELLS;

ALGINIC ACID; GLUCOSE; INSULIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DENSITY; CELL DIFFERENTIATION; CELL ENCAPSULATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DIFFUSION; EMBRYONIC STEM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INSULIN SYNTHESIS; MOUSE; NONHUMAN; POROSITY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE;

ALGINATES; ANIMALS; BIOCOMPATIBLE MATERIALS; BIOTECHNOLOGY; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; GLUCURONIC ACID; HEXURONIC ACIDS; INSULIN; INSULIN-SECRETING CELLS; MICE; PANCREAS;

EID: 70449113704     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2009.08.008     Document Type: Article

References (29)

1. Abbah S.A., Lu W.W., Chan D., Cheung K.M., Liu W.G., Zhao F., Li Z.Y., Leong J.C., and Luk K.D. Osteogenic behavior of alginate encapsulated bone marrow stromal cells: an in vitro study. J. Mater. Sci. Mater. Med. 19 5 (2008) 2113-2119
2. Barbucci R., and Leone G. Formation of defined microporous 3D structures starting from cross-linked hydrogels. J. Biomed. Mater. Res. B: Appl. Biomater. 68 2 (2004) 117-126
3. Blyszczuk P., and Wobus A.M. In vitro differentiation of embryonic stem cells into the pancreatic lineage. Methods Mol. Biol. 330 (2006) 373-385
4. Cui W., Barr G., Faucher K.M., Sun X.L., Safley S.A., Weber C.J., and Chaikof E.L. A membrane-mimetic barrier for islet encapsulation. Transplant. Proc. 36 4 (2004) 1206-1208
5. De Vos P., and Marchetti P. Encapsulation of pancreatic islets for transplantation in diabetes: the untouchable islets. Trends Mol. Med. 8 (2002) 363-366
6. Decho A.W. Imaging an alginate polymer gel matrix using atomic force microscopy. Carbohydr. Res. 315 (1999) 330-333
7. Figliuzzi M., Plati T., Cornolti R., Adobati F., Fagiani A., Rossi L., Remuzzi G., and Remuzzi A. Biocompatibility and function of microencapsulated pancreatic islets. Acta Biomater. 2 2 (2006) 221-227
8. Gelain F., Horii A., and Zhang S. Designer self-assembling peptide scaffolds for 3-D tissue cell cultures and regenerative medicine. Macromol. Biosci. 7 5 (2007) 544-551
9. Gerecht-Nir S., Cohen S., Ziskind A., and Itskovitz-Eldor J. Three-dimensional porous alginate scaffolds provide a conducive environment for generation of well-vascularized embryoid bodies from human embryonic stem cells. Biotechnol. Bioeng. 88 (2004) 313-320
10. Huang Y.X., Ren J., Chen C., Ren T.B., and Zhou X.Y. Preparation and properties of poly(lactide-co-glycolide) (PLGA)/nano-hydroxyapatite (NHA) scaffolds by thermally induced phase separation and rabbit MSCs culture on scaffolds. J. Biomater. Appl. 22 5 (2008) 409-432
11. Kaczorowski D.J., Patterson P.E., Jastromb W.E., and Shamblott M.J. Glucose-responsive insulin-producing cells from stem cells. Diab. Metab. Res. Rev. 18 6 (2002) 442-450
12. Lee C.T., and Lee Y.D. Preparation of porous biodegradable poly(lactide-co-glycolide)/hyaluronic acid blend scaffolds: characterization, in vitro cells culture and degradation behaviors. J. Mater. Sci. Mater. Med. 17 12 (2006) 1411-1420
13. Li X., Liu T., Song K., Yao L., Ge D., Bao C., Ma X., and Cui Z. Culture of neural stem cells in calcium alginate beads. Biotechnol. Prog. 22 6 (2006) 1683-1689
14. Lumelsky N., Blondel O., Laeng P., Velasco I., Ravin R., and McKay R. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 292 5520 (2001) 1389-1394
15. Maguire T., Novik E., Schloss R., and Yarmush M. Alginate-PLL microencapsulation: effect on the differentiation of embryonic stem cells into hepatocytes. Biotechnol. Bioeng. 93 3 (2006) 581-591
16. Maguire T., Davidovich A.E., Wallenstein E.J., Novik E., Sharma N., Pedersen H., Androulakis I.P., Schloss R., and Yarmush M. Control of hepatic differentiation via cellular aggregation in an alginate microenvironment. Biotechnol. Bioeng. 98 3 (2007) 631-644
17. Magyar J.P., Nemir M., Ehler E., Suter N., Perriard J.C., and Eppenberger H.M. Mass production of embryoid bodies in microbeads. Ann. N. Y. Acad. Sci. 944 (2001) 135-143
18. Mammarella E.J., and Rubiolo A.C. Crosslinking kinetics of cation-hydrocolloid gels. Chem. Eng. J. 94 1 (2003) 73-77
19. Miszta-Lane H., Mirbolooki M., James Shapiro A.M., and Lakey J.R. Stem cell sources for clinical islet transplantation in type 1 diabetes: embryonic and adult stem cells. Med. Hypotheses 67 4 (2006) 909-913
20. Moon J.S., Jeon H.M., Meng W., Akaike T., and Kang I.K. Morphology and metabolism of hepatocytes microencapsulated with acrylic terpolymer-alginate using gelatin and poly(vinyl alcohol) as extracellular matrices. J. Biomater. Sci. Polym. Ed. 16 10 (2005) 1245-1259
21. Omer A., Duvivier-Kali V., Fernandes J., Tchipashvili V., Colton C.K., and Weir G.C. Long-term normoglycemia in rats receiving transplants with encapsulated islets. Transplantation 79 1 (2005) 52-58
22. Ouyang A., Ng R., and Yang S.T. Long-term culturing of undifferentiated embryonic stem cells in conditioned media and three-dimensional fibrous matrices without extracellular matrix coating. Stem Cells 25 2 (2007) 447-454
23. Ren J., Ren T., Zhao P., Huang Y., and Pan K. Repair of mandibular defects using MSCs-seeded biodegradable polyester porous scaffolds. J. Biomater. Sci. Polym. Ed. 18 5 (2007) 505-517
24. Schroeder I.S., Kania G., Blyszczuk P., and Wobus A.M. Insulin-producing cells. Methods Enzymol. 418 (2006) 315-333
25. Shakesheff K., Cannizzaro S., and Langer R. Creating biomimetic micro-environments with synthetic polymer-peptide hybrid molecules. J. Biomater. Sci. Polym. Ed. 9 5 (1998) 507-518
26. Shi Y., Hou L., Tang F., Jiang W., Wang P., Ding M., and Deng H. Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid. Stem Cells 23 5 (2005) 656-662
27. Tal M., Silberstein A., and Nusser E. Why does Coomassie Brilliant Blue R interact differently with different proteins? A partial answer. J. Biol. Chem. 260 18 (1985) 9976-9980
28. Wijsman J., Atkison P., Mazaheri R., Garcia B., Paul T., Vose J., O'Shea G., and Stiller C. Histological and immunopathological analysis of recovered encapsulated allogeneic islets from transplanted diabetic BB/W rats. Transplantation 54 4 (1992) 588-592
29. Zimmermann U., Thurmer F., Jork A., Weber M., Mimietz S., Hillgartner M., Brunnenmeier F., Zimmermann H., Westphal I., Fuhr G., et al. A novel class of amitogenic alginate microcapsules for long-term immunoisolated transplantation. Ann. N. Y. Acad. Sci. 944 (2001) 199-215