Influence of genome-scale RNA structure disruption on the replication of murine norovirus - Similar replication kinetics in cell culture but attenuation of viral fitness in vivo

Nucleic Acids Research

Volumn 41, Issue 12, 2013, Pages 6316-6331

  McFadden, Nora ^a   Arias, Armando ^b,c   Dry, Inga ^a   Bailey, Dalan ^b,c,e   Witteveldt, Jeroen ^a   Evans, David J ^d   Goodfellow, Ian ^b,c   Simmonds, Peter ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF WARWICK   (United Kingdom)

^e INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; COCULTURE; CONTROLLED STUDY; GENE DISRUPTION; GENE FUNCTION; GENETIC ANALYSIS; IN VIVO STUDY; MACROPHAGE; NONHUMAN; NOROVIRUS; NUCLEOTIDE SEQUENCE; PERSISTENT VIRUS INFECTION; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; REPRODUCTIVE FITNESS; RNA SEQUENCE; RNA STRUCTURE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; UNINDEXED SEQUENCE; VIRUS ATTENUATION; VIRUS CULTURE; VIRUS REPLICATION;

ANIMALS; CELLS, CULTURED; CRICETINAE; GENETIC FITNESS; GENOME, VIRAL; KINETICS; MICE; MUTATION; NOROVIRUS; NUCLEIC ACID CONFORMATION; PHENOTYPE; RNA, VIRAL; VIRUS CULTIVATION; VIRUS REPLICATION;

EID: 84880220185     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt334     Document Type: Article

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