Activation of Gq proteins coupled with 5-HT2 receptors in rat cerebral cortical membranes assessed by antibody-capture scintillation proximity assay/[35S]GTPγS binding

Pharmacology

Volumn 92, Issue 1-2, 2013, Pages 2-10

  Odagaki, Yuji ^a   Toyoshima, Ryoichi ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

5 HT2 receptor; 35S GTP S binding; Cerebral cortex; G protein; M1 muscarinic receptor; Scintillation proximity assay

Indexed keywords

CARBACHOL; GQ PROTEIN; GUANOSINE 5 O (3 THIOTRIPHOSPHATE) S35; KETANSERIN; METITEPINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIRENZEPINE; PROTEIN; RADIOPHARMACEUTICAL AGENT; SEROTONIN; SEROTONIN 2 RECEPTOR; UNCLASSIFIED DRUG; ANTIBODY; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE 5' O (3 THIOTRIPHOSPHATE) S 35; MUSCARINIC M1 RECEPTOR;

ANIMAL EXPERIMENT; ANTIBODY CAPTURE SCINTILLATION; ARTICLE; BRAIN CORTEX; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SCINTILLATION; ANIMAL MODEL; ANTIGEN BINDING; BRAIN MEMBRANE; GTPGAMMAS BINDING ASSAY; PROTEIN PROTEIN INTERACTION; SIGNAL NOISE RATIO;

ANIMALS; ANTIBODIES; BIOLOGICAL ASSAY; CARBACHOL; CEREBRAL CORTEX; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN, 5-HT2; SEROTONIN; SEROTONIN ANTAGONISTS; SEROTONIN RECEPTOR AGONISTS; SULFUR RADIOISOTOPES;

EID: 84880183892     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000351745     Document Type: Article

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