Baicalin inhibits IL-17-mediated joint inflammation in murine adjuvant-induced arthritis

Clinical and Developmental Immunology

Volumn 2013, Issue , 2013, Pages

  Yang, Xue ^a   Yang, Ji ^b   Zou, Hejian ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BAICALIN; BETA ACTIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 17; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; FLAVONOID; FREUND ADJUVANT; HERBACEOUS AGENT; NONSTEROID ANTIINFLAMMATORY AGENT;

ADHESION; ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DOWN REGULATION; JOINT SWELLING; LYMPHOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCUTELLARIA BAICALENSIS; TH17 CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; PATHOLOGY; SIGNAL TRANSDUCTION; SPLEEN; SYNOVIUM; DRUG ANTAGONISM; DRUG EFFECT; EXPERIMENTAL ARTHRITIS; RHEUMATOID ARTHRITIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; DRUGS, CHINESE HERBAL; FLAVONOIDS; FREUND'S ADJUVANT; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-17; INTERLEUKIN-6; MALE; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; SPLEEN; SYNOVIAL MEMBRANE; TH17 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84880176520     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2013/268065     Document Type: Article

References (34)

1. Klareskog L., Catrina A. I., Paget S., Rheumatoid arthritis. The Lancet 2009 373 9664 659 672 2-s2.0-60249090304 10.1016/S0140-6736(09)60008-8
2. McInnes I. B., Schett G., Cytokines in the pathogenesis of rheumatoid arthritis. Nature Reviews Immunology 2007 7 6 429 442 2-s2.0-34249720998 10.1038/nri2094 (Pubitemid 46834849)
3. Xuzhu G., Komai-Koma M., Leung B. P., Howe H. S., McSharry C., McInnes I. B., Xu D., Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function. Annals of the Rheumatic Diseases 2012 71 1 129 135 2-s2.0-82955235595 10.1136/ard.2011.149831
4. Kim K., Cho M., Park M., Yoon C., Park S., Lee S., Kim H., Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kappaB-dependent pathway in patients with rheumatoid arthritis. Arthritis Research & Therapy 2005 7 1 R139 R148 2-s2.0-27644575496
5. Chabaud M., Durand J. M., Buchs N., Fossiez F., Page G., Frappart L., Miossec: P., Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis & Rheumatism 1999 42 963 970 (Pubitemid 29215007)
6. Simpson N., Gatenby P. A., Wilson A., Malik S., Fulcher D. A., Tangye S. G., Manku H., Vyse T. J., Roncador G., Huttley G. A., Goodnow C. C., Vinuesa C. G., Cook M. C., Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis and Rheumatism 2010 62 1 234 244 2-s2.0-74849138095 10.1002/art.25032
7. Ziolkowska M., Koc A., Luszczykiewicz G., Ksiezopolska-Pietrzak K., Klimczak E., Chwalinska-Sadowska H., Maslinski W., High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism. Journal of Immunology 2000 164 5 2832 2838 2-s2.0-0034161692 (Pubitemid 30115519)
8. Harrington L. E., Hatton R. D., Mangan P. R., Turner H., Murphy T. L., Murphy K. M., Weaver C. T., Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nature Immunology 2005 6 11 1123 1132 2-s2.0-27544490377 10.1038/ni1254 (Pubitemid 41541790)
9. Park H., Li Z., Yang X. O., Chang S. H., Nurieva R., Wang Y., Wang Y., Hood L., Zhu Z., Tian Q., Dong C., A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nature Immunology 2005 6 11 1133 1141 2-s2.0-27544465354 10.1038/ni1261 (Pubitemid 41541791)
10. Korn T., Bettelli E., Oukka M., Kuchroo V. K., IL-17 and Th17 cells. Annual Review of Immunology 2009 27 485 517 2-s2.0-61949463911 10.1146/annurev.immunol.021908.132710
11. Agarwal S., Misra R., Aggarwal A., Interleukin 17 levels are increased in juvenile idiopathic arthritis synovial fluid and induce synovial fibroblasts to produce proinflammatory cytokines and matrix metalloproteinases. Journal of Rheumatology 2008 35 3 515 519 2-s2.0-40649083317 (Pubitemid 351374430)
12. Shahrara S., Pickens S. R., Mandelin A. M. II, Karpus W. J., Huang Q., Kolls J. K., Pope R. M., IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction. Journal of Immunology 2010 184 8 4479 4487 2-s2.0-77952772125 10.4049/jimmunol.0901942
13. Lin C., Shieh D., The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin. American Journal of Chinese Medicine 1996 24 1 31 36 2-s2.0-0029704787 (Pubitemid 126765695)
14. Li B. Q., Fu T., Gong W., Dunlop N., Kung H., Yan Y., Kang J., Wang J. M., The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Immunopharmacology 2000 49 3 295 306 2-s2.0-0033829034 10.1016/S0162-3109(00)00244-7
15. Yang J., Yang X., Chu Y., Li M., Identification of Baicalin as an immunoregulatory compound by controlling TH17 cell differentiation. PLoS ONE 2011 6 2 2-s2.0-79951921353 10.1371/journal.pone.0017164 e17164
16. Lider O., Karin N., Shinitzky M., Cohen I. R., Therapeutic vaccination against adjuvant arthritis using autoimmune T cells treated with hydrostatic pressure. Proceedings of the National Academy of Sciences of the United States of America 1987 84 13 4577 4580 2-s2.0-0012825298 (Pubitemid 17097856)
17. Nanjundaiah S. M., Stains J. P., Moudgil K. D., Kinetics and interplay of mediators of inflammation-induced bone damage in the course of adjuvant arthritis. International Journal of Immunopathology and Pharmacology 2013 26 37 48
18. Watson M. L., Rao J. K., Gilkeson G. S., Ruiz P., Eicher E. M., Pisetsky D. S., Matsuzawa A., Rochelle J. M., Seldin M. F., Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. Journal of Experimental Medicine 1992 176 6 1645 1656 2-s2.0-0026471742 10.1084/jem.176.6.1645
19. Niki Y., Yamada H., Kikuchi T., Toyama Y., Matsumoto H., Fujikawa K., Tada N., Membrane-associated IL-1 contributes to chronic synovitis and cartilage destruction in human IL-1 α transgenic mice. Journal of Immunology 2004 172 1 577 584 2-s2.0-0347364681 (Pubitemid 38020515)
20. Ye P., Rodriguez F. H., Kanaly S., Stocking K. L., Schurr J., Schwarzenberger P., Oliver P., Huang W., Zhang P., Zhang J., Shellito J. E., Bagby G. J., Nelson S., Charrier K., Peschon J. J., Kolls J. K., Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. Journal of Experimental Medicine 2001 194 4 519 527 2-s2.0-17944364849 10.1084/jem.194.4.519 (Pubitemid 32835046)
21. Ivanov I. I., McKenzie B. S., Zhou L., Tadokoro C. E., Lepelley A., Lafaille J. J., Cua D. J., Littman D. R., The orphan nuclear receptor ROR γ t directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006 126 6 1121 1133 2-s2.0-33748588423 10.1016/j.cell.2006.07.035 (Pubitemid 44380299)
22. Zhou H., Wong Y. F., Wang J., Cai X., Liu L., Sinomenine ameliorates arthritis via MMPs, TIMPs, and cytokines in rats. Biochemical and Biophysical Research Communications 2008 376 2 352 357 2-s2.0-52949088275 10.1016/j.bbrc.2008.08.153
23. Wan J., Gong X., Zhang L., Li H., Zhou Y., Zhou Q., Protective effect of baicalin against Lipopolysaccharide/d-galactosamine-induced liver injury in mice by up-regulation of Heme oxygenase-1. European Journal of Pharmacology 2008 587 1-3 302 308 2-s2.0-44149100002 10.1016/j.ejphar.2008.02.081
24. Zeng Y., Song C., Ding X., Ji X., Yi L., Zhu K., Baicalin reduces the severity of experimental autoimmune encephalomyelitis. Brazilian Journal of Medical and Biological Research 2007 40 7 1003 1010 2-s2.0-34547787630 (Pubitemid 47232887)
25. Yang J., Yang X., Li: M., Baicalin, a natural compound, promotes regulatory T cell differentiation. BMC Complementary and Alternative Medicine 2012 12, article 64
26. Liu L., Gong L., Wang H., Xiao Y., Wu X., Zhang Y., Xue X., Qi X., Ren J., Baicalin inhibits macrophage activation by lipopolysaccharide and protects mice from endotoxin shock. Biochemical Pharmacology 2008 75 4 914 922 2-s2.0-38649087947 10.1016/j.bcp.2007.10.009
27. Zhu X., Liu Q., Wang M., Liang M., Yang X., Xu X., Zou H., Qiu J., Activation of Sirt1 by resveratrol inhibits TNF- α induced inflammation in fibroblasts. PloS one 2011 6 11 e27081 2-s2.0-84858188651
28. Yang J., Yang X., Zou H., Chu Y., Li M., Recovery of the immune balance between Th17 and regulatory T cells as a treatment for systemic lupus erythematosus. Rheumatology 2011 50 8 1366 1372 2-s2.0-84855172128
29. Yang J., Chu Y., Yang X., Gao D., Zhu L., Yang X., Wan L., Li M., Th17 and natural treg cell population dynamics in systemic lupus erythematosus. Arthritis and Rheumatism 2009 60 5 1472 1483 2-s2.0-66049151440 10.1002/art.24499
30. Kong N., Lan Q., Chen M., Antigen-specific transforming growth factor beta-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance. Arthritis & Rheumatism 2012 64 2548 2558
31. Krakauer T., Li B. Q., Young H. A., The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. FEBS Letters 2001 500 1-2 52 55 2-s2.0-0035968077 10.1016/S0014-5793(01)02584-4 (Pubitemid 32575317)
32. Liu S., Ma Z., Cai H., Li Q., Rong W., Kawano M., Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells. European Journal of Haematology 2010 84 2 137 144 2-s2.0-74049101564 10.1111/j.1600-0609. 2009.01365.x
33. Monte K., Wilson C., Shih F. F., Increased number and function of FoxP3 regulatory T cells during experimental arthritis. Arthritis and Rheumatism 2008 58 12 3730 3741 2-s2.0-57349104041 10.1002/art.24048
34. Yang X., Yang J., Chu Y., Wang J., Guan M., Zhu X., Xue Y., Zou H., T follicular helper cells mediate expansion of regulatory B cells via IL-21 in lupus-prone MRL/lpr mice. PLoS One 2013 8 e62855