Kinetics and interplay of mediators of inflammation-induced bone damage in the course of adjuvant arthritis

International Journal of Immunopathology and Pharmacology

Volumn 26, Issue 1, 2013, Pages 37-48

  Nanjundaiah, S M ^a   Stains, J P ^a   Moudgil, K D ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Adjuvant arthritis; Arthritis; Bone remodeling; Chemokines; Cytokines; Inflammation; OPG; Osteoclastogenesis; Osteoimmunology; Osteoprotegerin; Pathogenesis; RANKL

Indexed keywords

MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPONTIN; OSTEOPROTEGERIN; RANTES; CHEMOKINE; CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 6; KERATINOCYTE CHEMOATTRACTANT; LANTHANUM; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE INJURY; BONE REMODELING; CONTROLLED STUDY; DISEASE COURSE; LEUKOCYTE ACTIVATION; LEUKOCYTE MIGRATION; LYMPH NODE CELL; MALE; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; RAT; RHEUMATOID ARTHRITIS; HIND PAW; HISTOPATHOLOGY; INFLAMMATION; KINETICS; LEUKOCYTE; PROTEIN EXPRESSION; RADIOGRAPHY;

EID: 84880169027     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201302600104     Document Type: Article

References (34)

1. Astry B, Harberts E, Moudgil KD. A cytokine-centric view of the pathogenesis and treatment of autoimmune arthritis. J Interferon Cytokine Res 2011; 31(12):927-40.
2. Gorman CL, Cope AP. Immune-mediated pathways in chronic inflammatory arthritis. Best Pract Res Clin Rheumatol 2008; 22(2):221-38. (Pubitemid 351606942)
3. Hahn B. A pathophysiologic approach to the clinical management of arthritis and pain: current and future implications. J Clin Rheumatol 2004; 10(S):S3-4.
4. Lipsky PE. Rheumatoid arthritis. In: A. Fauci, E. Braunwald, D. Kasper, S. Hauser, D. longo, J. Jameson, J. Loscalzo, ed. Harrison's Principles of Internal Medicine. New York: McGraw Hill New York, NY, USA 2008:, 17th edition, 2083-92.
5. Steiner G, Tohidast-Akrad M, Witzmann G, et al. Cytokine production by synovial T cells in rheumatoid arthritis. Rheumatology (Oxford) 1999; 38(3):202-13. (Pubitemid 29507155)
6. Gravallese EM. Bone destruction in arthritis. Annals of the rheumatic diseases 2002; 61:(S):ii84-6.
7. Takayanagi H. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat Rev Immunol 2007; 7(4):292-304. (Pubitemid 46480961)
8. Holm BC, Lorentzen JC, Bucht A. Adjuvant oil induces waves of arthritogenic lymph node cells prior to arthritis onset. Clin Exp Immunol 2004; 137(1):59-64. (Pubitemid 38869778)
9. Newbould BB. Role of lymph nodes in adjuvant-induced arthritis in rats. Annals of the rheumatic diseases 1964; 23:392-6.
10. Kim EY, Chi HH, Bouziane M, Gaur A, Moudgil KD. Regulation of autoimmune arthritis Clin by the pro-inflammatory cytokine interferon-gamma. Immunol 2008; 127(1):98-106.
11. Rajaiah R, Puttabyatappa M, Polumuri SK, Moudgil KD. Interleukin-27 and interferon-gamma are involved in regulation of autoimmune arthritis. J Biol Chem 2011; 286(4):2817-25.
12. Stolina M, Bolon B, Middleton S, et al. The evolving systemic and local biomarker milieu at different stages of disease progression in rat adjuvant-induced arthritis. J Clin Immunol 2009; 29(2):158-74.
13. Moudgil KD, ChangTT, Eradat H, et al. Diversification of T cell responses to carboxy-terminal determinants within the 65-kD heat-shock protein is involved in regulation of autoimmune arthritis. J Exp Med 1997; 185(7):1307-16. (Pubitemid 27172911)
14. Yang YH, Rajaiah R, Lee DY, et al. Suppression of ongoing experimental arthritis by a chinese herbal formula (huo-luo-xiao-ling dan) involves changes in antigen-induced immunological and biochemical mediators of inflammation. Evid Based Complement Alternat Med 2011; 2011:642027.
15. Sellers RS, Peluso D, Morris EA. The effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the healing of full-thickness defects of articular cartilage. J Bone Joint Surg 1997; 79(10):1452-63. (Pubitemid 27459291)
16. Parfitt AM, Drezner MK, Glorieux FH, et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 1987; 2(6):595-610.
17. Venkatesha SH, Yu H, Rajaiah R, Tong L, Moudgil KD. Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses. J Biol Chem 2011; 286(17):15138-46.
18. Joosten LA, Helsen MM, Saxne T, van De Loo FA, Heinegard D, van Den Berg WB. IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation. J Immunol 1999; 163(9):5049-55. (Pubitemid 29501273)
19. Kolls JK, Linden A. Interleukin-17 family members and inflammation. Immunity 2004; 21(4):467-76. (Pubitemid 39370503)
20. Kotake S, Udagawa N, Takahashi N, et al. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 1999; 103(9): 1345-52. (Pubitemid 29218305)
21. Strand V, Kavanaugh AF. The role of interleukin-1 in bone resorption in rheumatoid arthritis. Rheumatology (Oxford) 2004; 43(S):iii10-iii6.
22. Martinez-Calatrava MJ, Prieto-Potin I, Roman-Bias JA, Tardio L, Largo R, Herrero-Beaumont G. RANKL synthesized by articular chondrocytes contributes to juxta-articular bone loss in chronic arthritis. Arthritis Res Ther 2012; 14(3):R149.
23. Zhang YH, Heulsmann A, Tondravi MM, Mukherjee A, Abu-Amer Y. Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways. J Biol Chem 2001; 276(1):563-8. (Pubitemid 32050352)
24. Dai SM, Nishioka K, Yudoh K. Interleukin (IL) 18 stimulates osteoclast formation through synovial T cells in rheumatoid arthritis: comparison with IL1 beta and tumour necrosis factor alpha. Ann Rheumat Dis 2004; 63(11):1379-86. (Pubitemid 39433939)
25. Nanjundaiah SM, Venkatesha SH, Yu H, Tong L, Stains JP, Moudgil KD. Celastrus and its bioactive celastrol protect against bone damage in autoimmune arthritis by modulating osteoimmune cross-talk. J Biol Chem 2012; 287(26):22216-26.
26. Lubberts E, van den Bersselaar L, Oppers-Walgreen B, et al. IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance. J Immunol 2003; 170(5):2655-62. (Pubitemid 36245658)
27. Hashizume M, Hayakawa N, Mihara M. IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17. Rheumatology (Oxford) 2008;47(11):1635-40.
28. Campbell IK, Bendele A, Smith DA, Hamilton JA. Granulocyte-macrophage colony stimulating factor exacerbates collagen induced arthritis in mice. Ann Rheumat Dis 1997; 56(6):364-8. (Pubitemid 27305424)
29. Nanjundaiah SM, Lee DY, Ma Z, et al. Modified huo-luo-xiao-ling dan suppresses adjuvant arthritis by inhibiting chemokines and matrix-degrading enzymes. Evid Based Complement Alternat Med 2012; 2012:589256.
30. Venkatesha SH, Astry B, Nanjundaiah SM, Yu H, Moudgil KD. Suppression of autoimmune arthritis by Celastrus-derived Celastrol through modulation of pro-inflammatory chemokines. Biorg Med Chem 2012; 20(17):5229-34.
31. Szekanecz Z, Halloran MM, Volin MV, et al. Temporal expression of inflammatory cytokines and chemokines in rat adjuvant-induced arthritis. Arthritis Rheum 2000; 43(6):1266-77. (Pubitemid 30416311)
32. Yu X, Huang Y, Collin-Osdoby P, Osdoby P. CCR1 chemokines promote the chemotactic recruitment, RANKL development, and motility of osteoclasts and are induced by inflammatory cytokines in osteoblasts. Bone Miner Res 2004; 19(12):2065-77. (Pubitemid 41103422)
33. Kim MS, Day CJ, Morrison NA. MCP-1 is induced by receptor activator of nuclear factor-{kappa} B ligand, promotes human osteoclast fusion, and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation. J Biol Chem 2005; 280(16):16163-9. (Pubitemid 40616742)
34. Schnyder B, Schnyder-Candrian S, Pansky A, et al. IL-17 reduces TNF-induced Rantes and VCAM-1 expression. Cytokine 2005; 31(3):191-202. (Pubitemid 40967902)