Adjuvant oil induces waves of arthritogenic lymph node cells prior to arthritis onset

Clinical and Experimental Immunology

Volumn 137, Issue 1, 2004, Pages 59-64

  Holm, B C ^a   Lorentzen, J C ^b   Bucht, A ^c  

^a LUND UNIVERSITY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c SWEDISH DEFENCE RESEARCH AGENCY   (Sweden)

Author keywords

Adjuvant arthritis; Adoptive transfer; DA rat; Lymph node; Squalene

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1BETA; SQUALENE;

ADJUVANT ARTHRITIS; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AXILLARY LYMPH NODE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE MARKER; FEMALE; INGUINAL REGION; LYMPH NODE CELL; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REACTION TIME;

ADJUVANTS, IMMUNOLOGIC; ADOPTIVE TRANSFER; ANIMALS; ARTHRITIS, EXPERIMENTAL; AXILLA; CONCANAVALIN A; FEMALE; FORELIMB; GENE EXPRESSION REGULATION; HYPERPLASIA; INTERFERON TYPE II; INTERLEUKINS; LYMPH NODES; OILS; PHENOTYPE; RATS; RATS, INBRED STRAINS; RNA, MESSENGER; SQUALENE; T-LYMPHOCYTES, HELPER-INDUCER; TIME FACTORS;

EID: 3042738406     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02498.x     Document Type: Article

References (20)

1. Klareskog L, Lorentzen JC, Padyukov L et al. Genes and environment in arthritis: can RA be prevented? Arthritis Res 2002; 4:S31-6.
2. Kleinau S, Erlandsson H, Holmdahl R et al. Adjuvant oils induce arthritis in the DA rat. I. Characterization of the disease and evidence for an immunological involvement. J Autoimmunity 1991; 4:871-80.
3. Carlson BC, Jansson ÅM, Larsson A et al. The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats. Am J Pathol 2000; 156:2057-65.
4. Svelander L, Müssener Å, Erlandsson-Harris H et al. Polyclonal Th1 cells transfer oil-induced arthritis. Immunology 1997; 91:260-5.
5. Jansson AM, Lorentzen JC, Bucht A. CD8+ cells suppress oil-induced arthritis. Clin Exp Immunol 2000; 120:532-6.
6. Holm BC, Svelander L, Bucht A et al. The arthritogenic adjuvant squalene does not accumulate in joints, but gives rise to pathogenic cells in both draining and non-draining lymph nodes. Clin Exp Immunol 2002; 127:430-5.
7. Greenhouse DD, Festing MFW, Hasan S et al. Genetic Monitoring of Inbred Strains of Rats. Stuttgart: Gustaf Fischer Verlag, 1990.
8. Svelander L, Holm BC, Bucht A et al. Responses of the rat immune system to arthritogenic adjuvant oil. Scand J Immunol 2001; 54:599-605.
9. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate- phenol-chloroform extraction. Anal Biochem 1987; 162:156-9.
10. Kinne RW, Brauer R, Stuhlmuller B et al. Macrophages in rheumatoid arthritis. Arthritis Res 2000; 2:189-202.
11. Holmdahl R, Lorentzen JC, Lu S et al. Arthritis induced in rats with nonimmunogenic adjuvants as models for rheumatoid arthritis. Immunol Rev 2001; 184:184-202.
12. Holm BC, Xu HW, Jacobsson L et al. Rats made congenic for Oia3 on chromosome 10 become susceptible to squalene-induced arthritis. Hum Mol Genet 2001; 10:565-72.
13. Vingsbo C, Jonsson R, Holmdahl R. Avridine-induced arthritis in rats; a T cell-dependent chronic disease influenced both by MHC genes and by non-MHC genes. Clin Exp Immunol 1995; 99:359-63.
14. Vingsbo C, Sahlstrand P, Brun JG et al. Pristane-induced arthritis in rats. Am J Pathol 1996; 149:1675-83.
15. Lorentzen JC, Klareskog L. Susceptibility of DA rats to arthritis induced with adjuvant oil or rat collagen is determined by genes both within and outside the major histocompatibility complex. Scand J Immunol 1996; 44:592-8.
16. Holmdahl R, Goldschmidt TJ, Kleinau S et al. Arthritis induced in rats with adjuvant oil is a genetically restricted, alpha beta T-cell dependent autoimmune disease. Immunology 1992; 76:197-202.
17. Kleinau S, Klareskog L. Oil-induced arthritis in DA rats: Passive transfer by T cells but not with serum. J Autoimmunity 1993; 6:449-58.
18. Müssener Å, Klareskog L, Lorentzen JC et al. TNF-α dominates cytokin mRNA expression in lymphoid tissues of rats developing collagen- and oil-induced arthritis. Scand J Immunol 1995; 42:128-34.
19. Mattsson L, Lorentzen JC, Svelander L et al. Immunization with alumcollagen II complex suppresses the development of collagen-induced arthritis in rats by deviating the immune response. Scand J Immunol 1997; 46:619-24.
20. Wendung U, Paul L, van der Zee R et al. A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10- producing T cells that cross-react with the mammalian self-hsp70 homologue. J Immunol 2000; 164:2711-7.