Analysis of classical swine fever virus RNA replication determinants using replicons

Journal of General Virology

Volumn 94, Issue PART8, 2013, Pages 1739-1748

  Risager, Peter Christian ^a   Fahnøe, Ulrik ^a   Gullberg, Maria ^a   Rasmussen, Thomas Bruun ^a   Belsham, Graham J ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; LUCIFERASE; NONSTRUCTURAL PROTEIN 3; RNA POLYMERASE; VIRUS RNA;

ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BACTERIAL STRAIN; CONTROLLED STUDY; ELECTROPORATION; ESCHERICHIA COLI; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PESTIVIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPLICON; RNA REPLICATION; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS RECOMBINATION; VIRUS STRAIN;

ANIMALS; CELL LINE; CLASSICAL SWINE FEVER VIRUS; ESCHERICHIA COLI; GENES, REPORTER; LUCIFERASES; PROTEIN BIOSYNTHESIS; RECOMBINATION, GENETIC; REPLICON; RNA, VIRAL; SHEEP; STAINING AND LABELING; TRANSCRIPTION, GENETIC; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84880164362     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.052688-0     Document Type: Article

References (41)

1. Behrens, S. E., Grassmann, C. W., Thiel, H. J., Meyers, G. & Tautz, N. (1998). Characterization of an autonomous subgenomic pestivirus RNA replicon. J Virol 72, 2364-2372.
2. Belsham, G. J., Nielsen, I., Normann, P., Royall, E. & Roberts, L. O. (2008). Monocistronic mRNAs containing defective hepatitis C virus like picornavirus internal ribosome entry site elements in their 59 untranslated regions are efficiently translated in cells by a cap dependent mechanism. RNA 14, 1671-1680.
3. Binder, M., Quinkert, D., Bochkarova, O., Klein, R., Kezmic, N., Bartenschlager, R. & Lohmann, V. (2007). Identification of determinants involved in initiation of hepatitis C virus RNA synthesis by using intergenotypic replicase chimeras. J Virol 81, 5270-5283.
4. Deng, R. & Brock, K. V. (1993). 59 and 39 untranslated regions of pestivirus genome: primary and secondary structure analyses. Nucleic Acids Res 21, 1949-1957.
5. Donnelly, M. L., Hughes, L. E., Luke, G., Mendoza, H., ten Dam, E., Gani, D. & Ryan, M. D. (2001). The 'cleavage' activities of foot-and mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences. J Gen Virol 82, 1027-1041.
6. Fletcher, S. P. & Jackson, R. J. (2002). Pestivirus internal ribosome entry site (IRES) structure and function: elements in the 59 untranslated region important for IRES function. J Virol 76, 5024-5033.
7. rns gene: a potential marker vaccine for intradermal application. Vet Res 37, 655-670.
8. Friis, M. B., Rasmussen, T. B. & Belsham, G. J. (2012). Modulation of translation initiation efficiency in classical swine fever virus. J Virol 86, 8681-8692.
9. Frolov, I., McBride, M. S. & Rice, C. M. (1998). cis-acting RNA elements required for replication of bovine viral diarrhea virus hepatitis C virus 59 nontranslated region chimeras. RNA 4, 1418-1435.
10. Fujimoto, R., Osakabe, T., Saito, M., Kurosawa, N. & Isobe, M. (2009). Minimum length of homology arms required for effective Red/ET recombination. Biosci Biotechnol Biochem 73, 2783-2786.
11. Gallei, A., Rumenapf, T., Thiel, H. J. & Becher, P. (2005). Characterization of helper virus-independent cytopathogenic classical swine fever virus generated by an in vivo RNA recombination system. J Virol 79, 2440-2448.
12. Greer, L. F., III & Szalay, A. A. (2002). Imaging of light emission from the expression of luciferases in living cells and organisms: a review. Luminescence 17, 43-74.
13. Jones, C. T., Murray, C. L., Eastman, D. K., Tassello, J. & Rice, C. M. (2007). Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus. J Virol 81, 8374-8383.
14. Leifer, I., Hoffmann, B., Hoper, D., Bruun Rasmussen, T., Blome, S., Strebelow, G., Horeth-Bontgen, D., Staubach, C. & Beer, M. (2010). Molecular epidemiology of current classical swine fever virus isolates of wild boar in Germany. J Gen Virol 91,687-2697.
15. Lindenbach, B. D., Thiel, H. & Rice, C. M. (editors) (2007). Fields Virology. Flaviviridae: The Viruses and Their Replication, 5th edn. Philadelphia: Lippincott-Raven.
16. Meyers, G. & Thiel, H. J. (1996). Molecular characterization of pestiviruses. Adv Virus Res 47, 53-118.
17. Mittelholzer, C., Moser, C., Tratschin, J. D. & Hofmann, M. A. (1997). Generation of cytopathogenic subgenomic RNA of classical swine fever virus in persistently infected porcine cell lines. Virus Res 51, 125-137.
18. Moser, C., Stettler, P., Tratschin, J. D. & Hofmann, M. A. (1999). Cytopathogenic and noncytopathogenic RNA replicons of classical swine fever virus. J Virol 73, 7787-7794.
19. Muyrers, J. P., Zhang, Y., Testa, G. & Stewart, A. F. (1999). Rapid modification of bacterial artificial chromosomes by ET-recombina tion. Nucleic Acids Res 27, 1555-1557.
20. Oleksiewicz, M. B., Rasmussen, T. B., Normann, P. & Uttenthal, A. (2003). Determination of the sequence of the complete open reading frame and the 59NTR of the Paderborn isolate of classical swine fever virus. Vet Microbiol 92, 311-325.
21. Pankraz, A., Thiel, H. J. & Becher, P. (2005). Essential and nonessential elements in the 39 nontranslated region of bovine viral diarrhea virus. J Virol 79, 9119-9127.
22. Rasmussen, T. B., Reimann, I., Hoffmann, B., Depner, K., Uttenthal, A. & Beer, M. (2008). Direct recovery of infectious pestivirus from a full-length RT-PCR amplicon. J Virol Methods 149, 330-333.
23. Rasmussen, T. B., Reimann, I., Uttenthal, A., Leifer, I., Depner, K., Schirrmeier, H. & Beer, M. (2010). Generation of recombinant pestiviruses using a full-genome amplification strategy. Vet Microbiol 142, 13-17.
24. Reimann, I., Meyers, G. & Beer, M. (2003). Trans-complementation of autonomously replicating Bovine viral diarrhea virus replicons with deletions in the E2 coding region. Virology 307, 213-227.
25. Rumenapf, T., Unger, G., Strauss, J. H. & Thiel, H. J. (1993). Processing of the envelope glycoproteins of pestiviruses. J Virol 67, 3288-3294.
26. Sheng, C., Xiao, M., Geng, X., Liu, J., Wang, Y. & Gu, F. (2007). Characterization of interaction of classical swine fever virus NS3 helicase with 39 untranslated region. Virus Res 129, 43-53.
27. Stech, J., Stech, O., Herwig, A., Altmeppen, H., Hundt, J., Gohrbandt, S., Kreibich, A., Weber, S., Klenk, H. D. & Mettenleiter, T. C. (2008). Rapid and reliable universal cloning of influenza A virus genes by target-primed plasmid amplification. Nucleic Acids Res 36, e139.
28. Suter, R., Summerfield, A., Thomann-Harwood, L. J., McCullough, K. C., Tratschin, J. D. & Ruggli, N. (2011). Immunogenic and replicative properties of classical swine fever virus replicon particles modified to induce IFN-a/b and carry foreign genes. Vaccine 29, 1491-1503.
29. Tamura, T., Sakoda, Y., Yoshino, F., Nomura, T., Yamamoto, N., Sato, Y., Okamatsu, M., Ruggli, N. & Kida, H. (2012). Selection of classical swine fever virus with enhanced pathogenicity reveals synergistic virulence determinants in E2 and NS4B. J Virol 86, 8602-8613.
30. Tannous, B. A., Kim, D. E., Fernandez, J. L., Weissleder, R. & Breakefield, X. O. (2005). Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther 11, 435-443.
31. Tautz, N., Elbers, K., Stoll, D., Meyers, G. & Thiel, H. J. (1997). Serine protease of pestiviruses: determination of cleavage sites. J Virol 71, 5415-5422.
32. Tautz, N., Harada, T., Kaiser, A., Rinck, G., Behrens, S. & Thiel, H. J. (1999). Establishment and characterization of cytopathogenic and noncytopathogenic pestivirus replicons. J Virol 73, 9422-9432.
33. Tautz, N., Kaiser, A. & Thiel, H. J. (2000). NS3 serine protease of bovine viral diarrhea virus: characterization of active site residues, NS4A cofactor domain, and protease-cofactor interactions. Virology 273, 351-363.
34. Terpstra, C. & de Smit, A. J. (2000). The 1997/1998 epizootic of swine fever in the Netherlands: control strategies under a non-vaccination regimen. Vet Microbiol 77, 3-15.
35. Uttenthal, A., Storgaard, T., Oleksiewicz, M. B. & de Stricker, K. (2003). Experimental infection with the Paderborn isolate of classical swine fever virus in 10-week-old pigs: determination of viral replication kinetics by quantitative RT-PCR, virus isolation and antigen ELISA. Vet Microbiol 92, 197-212.
36. Wang, P., Wang, Y., Zhao, Y., Zhu, Z., Yu, J., Wan, L., Chen, J. & Xiao, M. (2010). Classical swine fever virus NS3 enhances RNA-dependent RNA polymerase activity by binding to NS5B. Virus Res 148, 17-23.
37. Wei, D., Li, M., Zhang, X. & Xing, L. (2004). An improvement of the site-directed mutagenesis method by combination of megaprimer, one-side PCR and DpnI treatment. Anal Biochem 331, 401-403.
38. Weiland, E., Stark, R., Haas, B., Rumenapf, T., Meyers, G. & Thiel, H. J. (1990). Pestivirus glycoprotein which induces neutralizing antibodies forms part of a disulfide-linked heterodimer. J Virol 64, 3563-3569.
39. Widjojoatmodjo, M. N., van Gennip, H. G., de Smit, A. J. & Moormann, R. J. (1999). Comparative sequence analysis of classical swine fever virus isolates from the epizootic in the Netherlands in 1997-1998. Vet Microbiol 66, 291-299.
40. Xu, J., Mendez, E., Caron, P. R., Lin, C., Murcko, M. A., Collett, M. S. & Rice, C. M. (1997). Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication. J Virol 71, 5312-5322.
41. Yu, H., Grassmann, C. W. & Behrens, S. E. (1999). Sequence and structural elements at the 39 terminus of bovine viral diarrhea virus genomic RNA: functional role during RNA replication. J Virol 73, 3638-3648.