Selection of classical swine fever virus with enhanced pathogenicity reveals synergistic virulence determinants in E2 and NS4B

Journal of Virology

Volumn 86, Issue 16, 2012, Pages 8602-8613

  Tamura, Tomokazu ^a   Sakoda, Yoshihiro ^a   Yoshino, Fumi ^a   Nomura, Takushi ^a   Yamamoto, Naoki ^a   Sato, Yuka ^a   Okamatsu, Masatoshi ^a   Ruggli, Nicolas ^b   Kidaa, Hiroshi ^c  

^a HOKKAIDO UNIVERSITY   (Japan)

^b INSTITUTE OF VIROLOGY AND IMMUNOLOGY   (Switzerland)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN E2; NONSTRUCTURAL PROTEIN 4B; VIRUS RNA;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLASSICAL SWINE FEVER; CONTROLLED STUDY; EXPERIMENTAL PIG; IN VITRO STUDY; IN VIVO STUDY; NATURAL HOST; NONHUMAN; PESTIVIRUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA REPLICATION; VIRUS GENOME; VIRUS ISOLATION; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TITRATION; VIRUS VIRULENCE;

ADAPTATION, BIOLOGICAL; AMINO ACID SUBSTITUTION; ANIMALS; CATTLE; CELL LINE; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; DISEASE MODELS, ANIMAL; GUINEA PIGS; PALATINE TONSIL; SERIAL PASSAGE; SWINE; VACCINES, ATTENUATED; VIRAL ENVELOPE PROTEINS; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE; VIRULENCE FACTORS;

EID: 84865076620     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00551-12     Document Type: Article

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