Combined inhibition of complement (C5) and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis

Journal of Immunology

Volumn 191, Issue 2, 2013, Pages 819-827

  Barratt Due, Andreas ^a   Thorgersen, Ebbe B ^a   Egge, Kjetil ^a   Pischke, Søren ^a   Sokolov, Andrey ^a   Hellerud, Bernt C ^a   Lindstad, Julie K ^a   Pharo, Anne ^a   Bongoni, Anjan K ^b   Rieben, Robert ^b   Nunn, Miles ^c   Scott, Helge ^a   Mollnes, Tom E ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF BERN   (Switzerland)

^c CENTRE FOR ECOLOGY AND HYDROLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD14 ANTIBODY; CD14 ANTIGEN; COMPLEMENT COMPONENT C5; COMPLEMENT INHIBITOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LEUKOTRIENE B4; ORNITHODOROS MOUBATA COMPLEMENT INHIBITOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN ANTIBODY; THROMBIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICOAGULATION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMBINATION CHEMOTHERAPY; COMPLEMENT ACTIVATION; COMPLEMENT INHIBITION; CONTROLLED STUDY; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTION; EX VIVO STUDY; GRAM NEGATIVE SEPSIS; HEART RATE VARIABILITY; INFLAMMATION; INNATE IMMUNITY; LUNG ARTERY PRESSURE; MONOTHERAPY; NEUTROPHIL COUNT; NONHUMAN; ORNITHODOROS MOUBATA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SWINE; THROMBOGENICITY; THROMBOSIS; TREATMENT OUTCOME;

ANIMALS; ANTIGENS, CD11B; ANTIGENS, CD14; ANTITHROMBIN III; ARTERIAL PRESSURE; ARTHROPOD PROTEINS; CARRIER PROTEINS; COMPLEMENT C5; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEART RATE; HEMODYNAMICS; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; LEUKOCYTE COUNT; LEUKOTRIENE B4; NEUTROPHILS; PEPTIDE HYDROLASES; PLASMINOGEN ACTIVATOR INHIBITOR 1; SEPSIS; SUS SCROFA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84880128722     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201909     Document Type: Article

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