Slowing the Aging Process

Clinics in Geriatric Medicine

Volumn 29, Issue 3, 2013, Pages 721-730

  Wiggins, Jocelyn ^a   Bitzer, Markus ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Aging; Cellular processes; Chronic kidney disease; Genetic pathways

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALAGEBRIUM; AMINOGUANIDINE; CERULOPLASMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; KLOTHO PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MICRORNA; POLYPHENOL; RAPAMYCIN; RESVERATROL; SIRTUIN 1; SIRTUIN 3; SIRTUIN 6; SOMATOMEDIN C;

AGING; ANTIOXIDANT ACTIVITY; CALORIC RESTRICTION; CELL ORGANELLE; CHRONIC KIDNEY DISEASE; DNA DAMAGE; DRUG TARGETING; EPIGENETICS; GENE MUTATION; GENETIC CODE; HUMAN; KIDNEY DEVELOPMENT; KIDNEY DISEASE; KIDNEY FUNCTION; LONGEVITY; NONHUMAN; PROGERIA; REVIEW; SIGNAL TRANSDUCTION; TELOMERE;

AGING; CELLULAR PROCESSES; CHRONIC KIDNEY DISEASE; GENETIC PATHWAYS;

AGED; ANIMALS; CALORIC RESTRICTION; DNA DAMAGE; EPIGENOMICS; HUMANS; LIFE EXPECTANCY; LONGEVITY; NEPHRONS; RENAL INSUFFICIENCY, CHRONIC; SIGNAL TRANSDUCTION; TELOMERE;

EID: 84880098117     PISSN: 07490690     EISSN: 18798853     Source Type: Journal    
DOI: 10.1016/j.cger.2013.05.009     Document Type: Review

References (60)

1. Glassock R.J., Oreopoulos D.G. Aging and chronic kidney disease. Nephron Clin Pract 2011, 119(Suppl 1):c1.
2. Winearls C.G., Glassock R.J. Classification of chronic kidney disease in the elderly: pitfalls and errors. Nephron Clin Pract 2011, 119(Suppl 1):c2-c4.
3. Kenyon C., Chang J., Gensch E., et al. AC. elegans mutant that lives twice as long as wild type. Nature 1993, 366(6454):461-464.
4. Kimura K.D., Tissenbaum H.A., Liu Y., et al. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 1997, 277(5328):942-946.
5. Kenyon C.J. The genetics of ageing. Nature 2010, 464(7288):504-512.
6. Yuan R., Tsaih S.W., Petkova S.B., et al. Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. AgingCell 2009, 8(3):277-287.
7. Pawlikowska L., Hu D., Huntsman S., et al. Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity. Aging Cell 2009, 8(4):460-472.
8. Kapahi P., Zid B. TOR pathway: linking nutrient sensing to life span. Sci Aging Knowledge Environ 2004, 2004(36):PE34.
9. Kapahi P., Chen D., Rogers A.N., et al. With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab 2010, 11(6):453-465.
10. Harrison D.E., Strong R., Sharp Z.D., et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009, 460(7253):392-395.
11. Sinclair D.A., Guarente L. Extrachromosomal rDNA circles-a cause of aging in yeast. Cell 1997, 91(7):1033-1042.
12. Kaeberlein M., McVey M., Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 1999, 13(19):2570-2580.
13. Haigis M.C., Sinclair D.A. Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol 2010, 5:253-295.
14. Mostoslavsky R., Chua K.F., Lombard D.B., et al. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 2006, 124(2):315-329.
15. Kuro-o M., Matsumura Y., Aizawa H., et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 1997, 390:45-51.
16. Kurosu H., Yamamoto M., Clark J.D., et al. Suppression of aging in mice by the hormoneklotho. Science 2005, 309:1829-1833.
17. Wang Y., Sun Z. Current understanding of klotho. Ageing Res Rev 2009, 8:43-51.
18. Kuro-o M. Klotho and aging. Biochim Biophys Acta 2009, 1790:1049-1058.
19. Arking D.E., Krebsova A., Macek M., et al. Association of human aging with a functional variant of klotho. Proc Natl Acad Sci USA 2002, 99:856-861.
20. Hoeijmakers J.H. DNA damage, aging, and cancer. NEngl J Med 2009, 361(15):1475-1485.
21. Delahunt B., Stehbens W.E., Gilbert-Barness E., et al. Progeria kidney has abnormal mesangial collagen distribution. Pediatr Nephrol 2000, 15(3-4):279-285.
22. Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005, 120(4):513-522.
23. Westhoff J.H., Schildhorn C., Jacobi C., et al. Telomere shortening reduces regenerative capacity after acute kidney injury. JAm Soc Nephrol 2010, 21(2):327-336.
24. Feest T.G., Round A., Hamad S. Incidence of severe acute renal failure in adults: results of a community based study. BMJ 1993, 306(6876):481-483.
25. Wardle E.N. Acute renal failure and multiorgan failure. Nephrol Dial Transplant 1994, 9(Suppl 4):104-107.
26. Schmitt R., Coca S., Kanbay M., et al. Recovery of kidney function after acute kidneyinjury in the elderly: a systematic review and meta-analysis. Am J Kidney Dis 2008, 52(2):262-271.
27. Wiggins J.E., Patel S.R., Shedden K.A., et al. NFkappaB promotes inflammation, coagulation, and fibrosis in the aging glomerulus. JAm Soc Nephrol 2010, 21(4):587-597.
28. Smith-Vikos T., Slack F.J. MicroRNAs and their roles in aging. JCell Sci 2012, 125:7-17.
29. Leung A.K., Sharp P.A. MicroRNA functions in stress responses. Mol Cell 2010, 40:205-215.
30. Karolina D.S., Wintour E.M., Bertram J., et al. Riboregulators in kidney development and function. Biochimie 2010, 92(3):217-225.
31. Harvey S.J., Jarad G., Cunningham J., et al. Podocyte-specific deletion of Dicer alters cytoskeletal dynamics and causes glomerular disease. JAm Soc Nephrol 2008, 19:2069-2075.
32. Grillari J., Grillari-Voglauer R. Novel modulators of senescence, aging and longevity:small non-coding RNAs enter the stage. Exp Gerontol 2010, 45(4):302-311.
33. Geanacopoulos M. The determinants in lifespan in the nematode Caenorhabditis elegans: a short primer. Sci Prog 2004, 87(Pt 4):227-247.
34. Edgar D., Trifunovic A. The mtDNA mutator mouse: dissecting mitochondrial involvement in aging. Aging (Albany NY) 2009, 1(12):1028-1032.
35. Cuervo A.M., Bergamini E., Brunk U.T., et al. Autophagy and aging: the importance of maintaining "clean" cells. Autophagy 2005, 1(3):131-140.
36. Hartleben B., Gödel M., Meyer-Schwesinger C., et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. JClin Invest 2010, 120(4):1084-1096.
37. Muller F.L., Lustgarten M.S., Jang Y., et al. Trends in oxidative aging theories. Free Radic Biol Med 2007, 43(4):477-503.
38. Ferrucci L. The Baltimore Longitudinal Study of Aging (BLSA): a 50-year-long journey and plans for the future. JGerontol A Biol Sci Med Sci 2008, 63(12):1416-1419.
39. Vlassara H., Uribarri J., Ferrucci L., et al. Identifying advanced glycation end products as a major source of oxidants in aging: implications for the management and/or prevention of reduced renal function in elderly persons. Semin Nephrol 2009, 29(6):594-603.
40. Makita Z., Yanagisawa K., Kuwajima S., et al. Advanced glycation endproducts and diabetic nephropathy. JDiabet Complications 1995, 9(4):265-268.
41. Uribarri J., Peppa M., Cai W., et al. Restriction of dietary glycotoxins reduces excessive advanced glycation endproducts in renal failure patients. JAm Soc Nephrol 2003, 14(3):728-731.
42. Navarro-Díaz M., Serra A., López D., et al. Obesity, inflammation, and kidney disease. Kidney Int Suppl 2008, (111):S15-S18.
43. Muntner P., Coresh J., Smith J.C., et al. Plasma lipids and risk of developing renal dysfunction: the atherosclerosis risk in communities study. Kidney Int 2000, 58(1):293-301.
44. Okamura D.M., Pennathur S., Pasichnyk K., et al. CD36 regulates oxidative stress and inflammation in hypercholesterolemic CKD. JAm Soc Nephrol 2009, 20(3):495-505.
45. Wiggins J.E., Goyal M., Wharram B.L., et al. Antioxidant ceruloplasmin is expressed by glomerular parietal epithelial cells and secreted into urine in association with glomerular aging and high-calorie diet. JAm Soc Nephrol 2006, 17(5):1382-1387.
46. Thornalley P.J. Advanced glycation end products in renal failure. JRen Nutr 2006, 16(3):178-184. [review].
47. Thornalley P.J. Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts. Arch Biochem Biophys 2003, 419(1):31-40. [review].
48. Bolton W.K., Cattran D.C., Williams M.E., ACTION I Investigator Group, et al. Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy. Am J Nephrol 2004, 24(1):32-40.
49. Forbes J.M., Yee L.T., Thallas V., et al. Advanced glycation end product interventionsreduce diabetes-accelerated atherosclerosis. Diabetes 2004, 53(7):1813-1823.
50. Bakris G.L., Bank A.J., Kass D.A., et al. Advanced glycation end-product cross-link breakers. A novel approach to cardiovascular pathologies related to the aging process. Am J Hypertens 2004, 17(12 Pt 2):23S-30S.
51. Sabbagh M.N., Agro A., Bell J., et al. PF-04494700, an oral inhibitor of receptor for advanced glycation end products (RAGE), in Alzheimer disease. Alzheimer Dis Assoc Disord 2011, 25(3):206-212.
52. Peng X., Ma J., Chen F., et al. Naturally occurring inhibitors against the formation of advanced glycation end-products. Food Funct 2011, 2(6):289-301.
53. McCay C.M., Crowell M.F., Maynard L.A. The effect of retarded growth upon the length of life span and upon the ultimate body size. Nutrition 1935, 5:155.
54. Yu B.P., Masoro E.J., McMahan C.A. Nutritional influences on aging of Fischer 344 rats: 1. Physical, metabolic and longevity characteristics. JGerontol 1985, 40(6):657-670.
55. Maeda H., Gleiser C.A., Masoro E.J., et al. Nutritional influences on aging of Fischer 344 rats: II Pathology. JGerontol 1985, 40(6):671-688.
56. Masoro E.J. Dietary restriction and aging. JAm Geriatr Soc 1993, 41:994-999.
57. Nadon N.L. Of mice and monkeys: National Institute on Aging resources supporting the use of animal models in biogerontology research. JGerontol A Biol Sci Med Sci 2006, 61(8):813-815.
58. Colman R.J., Anderson R.M., Johnson S.C., et al. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 2009, 325(5937):201-204.
59. Wiggins J.E., Goyal M., Sanden S.K., et al. Podocyte hypertrophy, "adaptation," and"decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction. JAm Soc Nephrol 2005, 16(10):2953-2966.
60. Redman L.M., Ravussin E. Caloric restriction in humans: impact on physiological, psychological, and behavioral outcomes. Antioxid Redox Signal 2011, 14(2):275-287.