Cerebrospinal fluid brain injury biomarkers in children: A multicenter study

Pediatric Neurology

Volumn 49, Issue 1, 2013, Pages

  Shahim, Pashtun ^a   Darin, Niklas ^c   Andreasson, Ulf ^a   Blennow, Kaj ^a   Jennions, Elizabeth ^d   Lundgren, Johan ^e   Månsson, Jan Eric ^a   Naess, Karin ^f   Törnhage, Carl Johan ^g   Zetterberg, Henrik ^a,b   Mattsson, Niklas ^a,h  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c QUEEN SILVIA CHILDREN'S HOSPITAL   (Sweden)

^d Sodra Alvborgs Hospital   (Sweden)

^e LUND UNIVERSITY HOSPITAL   (Sweden)

^f KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^g SKARABORG HOSPITAL   (Sweden)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROFILAMENT PROTEIN; TAU PROTEIN;

ARTICLE; BRAIN INJURY; CENTRAL NERVOUS SYSTEM INFECTION; CENTRAL NERVOUS SYSTEM TUMOR; CEREBROSPINAL FLUID; CHILD; CHILDHOOD INJURY; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EPILEPTIC STATE; EVALUATION; FEMALE; FOCAL EPILEPSY; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MOTOR DYSFUNCTION; MULTICENTER STUDY; NEUROCHEMISTRY; NEUROFILAMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; RETROSPECTIVE STUDY; SCHOOL CHILD;

EID: 84880077757     PISSN: 08878994     EISSN: 18735150     Source Type: Journal    
DOI: 10.1016/j.pediatrneurol.2013.02.015     Document Type: Article

References (37)

1. N. Mattsson CSF biomarkers in neurodegenerative diseases Clin Chem Lab Med 49 3 2011 345 352
2. M. Morris, S. Maeda, K. Vossel, and L. Mucke The many faces of tau Neuron 70 3 2011 410 426
3. M. Vandermeeren, M. Mercken, and E. Vanmechelen Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay J Neurochem 61 5 1993 1828 1834
4. K. Muszynska-Roslan, M. Krawczuk-Rybak, P.T. Protas, and A. Holownia Level of tau protein in children treated for acute lymphoblastic leukemia Pediatr Neurol 34 5 2006 367 371
5. S.W. Van Gool, E. Van Kerschaver, and P. Brock Disease- and treatment-related elevation of the neurodegenerative marker tau in children with hematological malignancies Leukemia 14 12 2000 2076 2084
6. J.M. de Bont, H. Vanderstichele, R.E. Reddingius, R. Pieters, and S.W. van Gool Increased total-Tau levels in cerebrospinal fluid of pediatric hydrocephalus and brain tumor patients Eur J Paediatr Neurol 12 4 2008 334 341
7. D. Gavhed, S.O. Akefeldt, and G. Osterlundh Biomarkers in the cerebrospinal fluid and neurodegeneration in Langerhans cell histiocytosis Pediatr Blood Cancer 53 7 2009 1264 1270
8. N. Mattsson, H. Zetterberg, and S. Bianconi Gamma-secretase-dependent amyloid-beta is increased in Niemann-Pick type C: A cross-sectional study Neurology 76 4 2011 366 372
9. G.W. Kay, M.M. Verbeek, J.M. Furlong, M.A. Willemsen, and D.N. Palmer Neuropeptide changes and neuroactive amino acids in CSF from humans and sheep with neuronal ceroid lipofuscinoses (NCLs, Batten disease) Neurochem Int 55 8 2009 783 788
10. R. Kristjansdottir, P. Uvebrant, A. Lekman, and J.E. Mansson Cerebrospinal fluid markers in children with cerebral white matter abnormalities Neuropediatrics 32 4 2001 176 182
11. R.L. Friede, and T. Samorajski Axon caliber related to neurofilaments and microtubules in sciatic nerve fibers of rats and mice Anat Rec 167 4 1970 379 387
12. R. Kristjansdottir, P. Uvebrant, and L. Rosengren Glial fibrillary acidic protein and neurofilament in children with cerebral white matter abnormalities Neuropediatrics 32 6 2001 307 312
13. L.F. Eng, J.J. Vanderhaeghen, A. Bignami, and B. Gerstl An acidic protein isolated from fibrous astrocytes Brain Res 28 2 1971 351 354
14. A. Bignami, L.F. Eng, D. Dahl, and C.T. Uyeda Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence Brain Res 43 2 1972 429 435
15. F. Dubos, F. Moulin, and V. Gajdos Serum procalcitonin and other biologic markers to distinguish between bacterial and aseptic meningitis J Pediatr 149 1 2006 72 76
16. M. Djukic, C. Schmidt-Samoa, and P. Lange Cerebrospinal fluid findings in adults with acute Lyme neuroborreliosis J Neurol 259 4 2012 630 636
17. F. Deisenhammer, A. Bartos, and R. Egg Guidelines on routine cerebrospinal fluid analysis. Report from an EFNS task force Eur J Neurol 13 9 2006 913 922
18. H.P. Garges, M.A. Moody, and C.M. Cotten Neonatal meningitis: What is the correlation among cerebrospinal fluid cultures, blood cultures, and cerebrospinal fluid parameters? Pediatrics 117 4 2006 1094 1100
19. R.W. Lenfestey, P.B. Smith, and M.A. Moody Predictive value of cerebrospinal fluid parameters in neonates with intraventricular drainage devices J Neurosurg 107 3 suppl 2007 209 212
20. H. Tumani, G. Nolker, and H. Reiber Relevance of cerebrospinal fluid variables for early diagnosis of neuroborreliosis Neurology 45 9 1995 1663 1670
21. B. Hagberg, P. Sourander, and L. Svennerholm Diagnosis of Krabbe's infantile leucodystrophy J Neurol Neurosurg Psychiatry 26 1963 195 198
22. P. Shahim, J.E. Mansson, N. Darin, H. Zetterberg, and N. Mattsson Cerebrospinal fluid biomarkers in neurological diseases in children Eur J Paediatr Neurol 17 1 2013 7 13
23. M. Tullberg, K. Blennow, J.E. Mansson, P. Fredman, M. Tisell, and C. Wikkelso Ventricular cerebrospinal fluid neurofilament protein levels decrease in parallel with white matter pathology after shunt surgery in normal pressure hydrocephalus Eur J Neurol 14 3 2007 248 254
24. K. Blennow, A. Wallin, H. Agren, C. Spenger, J. Siegfried, and E. Vanmechelen Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease? Molec Chem Neuropath 26 3 1995 231 245
25. N. Mattsson, K. Savman, G. Osterlundh, K. Blennow, and H. Zetterberg Converging molecular pathways in human neural development and degeneration Neurosci Res 66 3 2010 330 332
26. L.E. Rosengren, G. Ahlsen, M. Belfrage, C. Gillberg, K.G. Haglid, and A. Hamberger A sensitive ELISA for glial fibrillary acidic protein: application in CSF of children J Neurosci Meth 44 2-3 1992 113 119
27. L.E. Rosengren, J.E. Karlsson, J.O. Karlsson, L.I. Persson, and C. Wikkelso Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF J Neurochem 67 5 1996 2013 2018
28. M. Bylesjo, M. Rantalainen, J.K. Nicholson, E. Holmes, and J. Trygg K-OPLS package: Kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space BMC Bioinformatics 9 2008 106
29. U. Andreasson, E. Portelius, J. Pannee, H. Zetterberg, and K. Blennow Multiplexing and multivariate analysis in neurodegeneration Methods 56 4 2012 464 470
30. H. Zetterberg, N. Mattsson, L.M. Shaw, and K. Blennow Biochemical markers in Alzheimer's disease clinical trials Biomarkers Med 4 1 2010 91 98
31. K. Blennow, M.J. de Leon, and H. Zetterberg Alzheimer's disease Lancet 368 9533 2006 387 403
32. C.A. Gurnett, M. Landt, and M. Wong Analysis of cerebrospinal fluid glial fibrillary acidic protein after seizures in children Epilepsia 44 11 2003 1455 1458
33. J. Palmio, J. Suhonen, T. Keranen, J. Hulkkonen, J. Peltola, and T. Pirttila Cerebrospinal fluid tau as a marker of neuronal damage after epileptic seizure Seizure 18 7 2009 474 477
34. K. Rejdak, J. Kuhle, and S. Ruegg Neurofilament heavy chain and heat shock protein 70 as markers of seizure-related brain injury Epilepsia 53 5 2012 922 927
35. C.M. DeGiorgio, U. Tomiyasu, P.S. Gott, and D.M. Treiman Hippocampal pyramidal cell loss in human status epilepticus Epilepsia 33 1 1992 23 27
36. C.M. DeGiorgio, P.S. Gott, A.L. Rabinowicz, C.N. Heck, T.D. Smith, and J.D. Correale Neuron-specific enolase, a marker of acute neuronal injury, is increased in complex partial status epilepticus Epilepsia 37 7 1996 606 609
37. N. Tanuma, R. Miyata, and S. Kumada The axonal damage marker tau protein in the cerebrospinal fluid is increased in patients with acute encephalopathy with biphasic seizures and late reduced diffusion Brain Develop 32 6 2010 435 439