Dynamics of the antigen-binding grooves in CD1 proteins: Reversible hydrophobic collapse in the lipid-free state

Journal of Biological Chemistry

Volumn 288, Issue 27, 2013, Pages 19528-19536

  Garzón, Diana ^a   Anselmi, Claudio ^a   Bond, Peter J ^b   Faraldo Gómez, José D ^a  

^a MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN-BINDING; CELLULAR INTERNALIZATION; HYDROPHOBIC CAVITIES; HYDROPHOBIC COLLAPSE; INTRACELLULAR PATHWAYS; LIPID TRANSFER PROTEIN; MOLECULAR DYNAMICS SIMULATIONS; STRUCTURAL FEATURE;

ANTIBODIES; CELL MEMBRANES; ENZYME ACTIVITY; HYDROPHOBICITY; LIPIDS; MOLECULAR DYNAMICS; RECYCLING;

ANTIGENS;

CD1 ANTIGEN; CD1B ANTIGEN; CD1C ANTIGEN; CD1D ANTIGEN; CD1E ANTIGEN; T6 ANTIGEN; UNCLASSIFIED DRUG;

ALLOSTERISM; ALPHA HELIX; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; HUMAN; HYDROPHOBICITY; INTERNALIZATION; LIPID TRANSPORT; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; STATIC ELECTRICITY;

ADAPTIVE IMMUNITY; ALLOSTERIC REGULATION; ANTIGEN PRESENTATION; CELLULAR IMMUNE RESPONSE; HYDROPHOBIC COLLAPSE; LIPID BINDING PROTEIN; MOLECULAR DYNAMICS;

ANTIGENS; ANTIGENS, CD1; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPIDS; MOLECULAR DYNAMICS SIMULATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84880070645     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.470179     Document Type: Article

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