-
1
-
-
0017760671
-
Hereditary multiple fibrofolliculomas with trichodiscomas and acrochordons
-
Birt AR, Hogg GR, Dube WJ, (1977) Hereditary multiple fibrofolliculomas with trichodiscomas and acrochordons. Arch Dermatol 113: 1674-1677.
-
(1977)
Arch Dermatol
, vol.113
, pp. 1674-1677
-
-
Birt, A.R.1
Hogg, G.R.2
Dube, W.J.3
-
2
-
-
0035939821
-
Birt-Hogg-Dube syndrome: mapping of a novel hereditary neoplasia gene to chromosome 17p12-q11.2
-
Khoo SK, Bradley M, Wong FK, Hedblad MA, Nordenskjold M, et al. (2001) Birt-Hogg-Dube syndrome: mapping of a novel hereditary neoplasia gene to chromosome 17p12-q11.2. Oncogene 20: 5239-5242.
-
(2001)
Oncogene
, vol.20
, pp. 5239-5242
-
-
Khoo, S.K.1
Bradley, M.2
Wong, F.K.3
Hedblad, M.A.4
Nordenskjold, M.5
-
3
-
-
70849136880
-
Birt-Hogg-Dube syndrome: diagnosis and management
-
Menko FH, van Steensel MA, Giraud S, Friis-Hansen L, Richard S, et al. (2009) Birt-Hogg-Dube syndrome: diagnosis and management. Lancet Oncol 10: 1199-1206.
-
(2009)
Lancet Oncol
, vol.10
, pp. 1199-1206
-
-
Menko, F.H.1
van Steensel, M.A.2
Giraud, S.3
Friis-Hansen, L.4
Richard, S.5
-
4
-
-
0027380152
-
Bilateral renal cell carcinoma in the Birt-Hogg-Dube syndrome
-
Roth JS, Rabinowitz AD, Benson M, Grossman ME, (1993) Bilateral renal cell carcinoma in the Birt-Hogg-Dube syndrome. J Am Acad Dermatol 29: 1055-1056.
-
(1993)
J Am Acad Dermatol
, vol.29
, pp. 1055-1056
-
-
Roth, J.S.1
Rabinowitz, A.D.2
Benson, M.3
Grossman, M.E.4
-
5
-
-
0031855915
-
Hereditary multiple fibrofolliculomas, trichodiscomas and acrochordons: syndrome of Birt-Hogg-Dube
-
Scalvenzi M, Argenziano G, Sammarco E, Delfino M, (1998) Hereditary multiple fibrofolliculomas, trichodiscomas and acrochordons: syndrome of Birt-Hogg-Dube. J Eur Acad Dermatol Venereol 11: 45-47.
-
(1998)
J Eur Acad Dermatol Venereol
, vol.11
, pp. 45-47
-
-
Scalvenzi, M.1
Argenziano, G.2
Sammarco, E.3
Delfino, M.4
-
6
-
-
0034821623
-
Birt-Hogg-Dube syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2
-
Schmidt LS, Warren MB, Nickerson ML, Weirich G, Matrosova V, et al. (2001) Birt-Hogg-Dube syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2. Am J Hum Genet 69: 876-882.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 876-882
-
-
Schmidt, L.S.1
Warren, M.B.2
Nickerson, M.L.3
Weirich, G.4
Matrosova, V.5
-
7
-
-
0032718182
-
Birt-Hogg-Dube syndrome: a novel marker of kidney neoplasia
-
Toro JR, Glenn G, Duray P, Darling T, Weirich G, et al. (1999) Birt-Hogg-Dube syndrome: a novel marker of kidney neoplasia. Arch Dermatol 135: 1195-1202.
-
(1999)
Arch Dermatol
, vol.135
, pp. 1195-1202
-
-
Toro, J.R.1
Glenn, G.2
Duray, P.3
Darling, T.4
Weirich, G.5
-
8
-
-
0000939691
-
Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome
-
Nickerson ML, Warren MB, Toro JR, Matrosova V, Glenn G, et al. (2002) Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome. Cancer Cell 2: 157-164.
-
(2002)
Cancer Cell
, vol.2
, pp. 157-164
-
-
Nickerson, M.L.1
Warren, M.B.2
Toro, J.R.3
Matrosova, V.4
Glenn, G.5
-
9
-
-
21044457377
-
Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dube syndrome
-
Schmidt LS, Nickerson ML, Warren MB, Glenn GM, Toro JR, et al. (2005) Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dube syndrome. Am J Hum Genet 76: 1023-1033.
-
(2005)
Am J Hum Genet
, vol.76
, pp. 1023-1033
-
-
Schmidt, L.S.1
Nickerson, M.L.2
Warren, M.B.3
Glenn, G.M.4
Toro, J.R.5
-
10
-
-
45249103326
-
BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dube syndrome: a new series of 50 families and a review of published reports
-
Toro JR, Wei MH, Glenn GM, Weinreich M, Toure O, et al. (2008) BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dube syndrome: a new series of 50 families and a review of published reports. J Med Genet 45: 321-331.
-
(2008)
J Med Genet
, vol.45
, pp. 321-331
-
-
Toro, J.R.1
Wei, M.H.2
Glenn, G.M.3
Weinreich, M.4
Toure, O.5
-
11
-
-
38449122032
-
Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys
-
Baba M, Furihata M, Hong SB, Tessarollo L, Haines DC, et al. (2008) Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. J Natl Cancer Inst 100: 140-154.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 140-154
-
-
Baba, M.1
Furihata, M.2
Hong, S.B.3
Tessarollo, L.4
Haines, D.C.5
-
12
-
-
55849108854
-
Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia
-
Chen J, Futami K, Petillo D, Peng J, Wang P, et al. (2008) Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia. PLoS One 3: e3581.
-
(2008)
PLoS One
, vol.3
-
-
Chen, J.1
Futami, K.2
Petillo, D.3
Peng, J.4
Wang, P.5
-
13
-
-
64049090204
-
The role of the Birt-Hogg-Dube protein in mTOR activation and renal tumorigenesis
-
Hartman TR, Nicolas E, Klein-Szanto A, Al-Saleem T, Cash TP, et al. (2009) The role of the Birt-Hogg-Dube protein in mTOR activation and renal tumorigenesis. Oncogene 28: 1594-1604.
-
(2009)
Oncogene
, vol.28
, pp. 1594-1604
-
-
Hartman, T.R.1
Nicolas, E.2
Klein-Szanto, A.3
Al-Saleem, T.4
Cash, T.P.5
-
14
-
-
77953719290
-
Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling
-
Hong SB, Oh H, Valera VA, Stull J, Ngo DT, et al. (2010) Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling. Mol Cancer 9: 160.
-
(2010)
Mol Cancer
, vol.9
, pp. 160
-
-
Hong, S.B.1
Oh, H.2
Valera, V.A.3
Stull, J.4
Ngo, D.T.5
-
15
-
-
38149094921
-
The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dube gene pathway
-
Yang Y, Padilla-Nash HM, Vira MA, Abu-Asab MS, Val D, et al. (2008) The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dube gene pathway. Cancer Genet Cytogenet 180: 100-109.
-
(2008)
Cancer Genet Cytogenet
, vol.180
, pp. 100-109
-
-
Yang, Y.1
Padilla-Nash, H.M.2
Vira, M.A.3
Abu-Asab, M.S.4
Val, D.5
-
16
-
-
33750293584
-
Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling
-
Baba M, Hong SB, Sharma N, Warren MB, Nickerson ML, et al. (2006) Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling. Proc Natl Acad Sci U S A 103: 15552-15557.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 15552-15557
-
-
Baba, M.1
Hong, S.B.2
Sharma, N.3
Warren, M.B.4
Nickerson, M.L.5
-
17
-
-
70349092228
-
Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway
-
Piao X, Kobayashi T, Wang L, Shiono M, Takagi Y, et al. (2009) Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway. Biochem Biophys Res Commun 389: 16-21.
-
(2009)
Biochem Biophys Res Commun
, vol.389
, pp. 16-21
-
-
Piao, X.1
Kobayashi, T.2
Wang, L.3
Shiono, M.4
Takagi, Y.5
-
18
-
-
71549132196
-
Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dube gene product
-
Wang L, Kobayashi T, Piao X, Shiono M, Takagi Y, et al. (2010) Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dube gene product. FEBS Lett 584: 39-43.
-
(2010)
FEBS Lett
, vol.584
, pp. 39-43
-
-
Wang, L.1
Kobayashi, T.2
Piao, X.3
Shiono, M.4
Takagi, Y.5
-
19
-
-
42649092576
-
Identification and characterization of a novel folliculin-interacting protein FNIP2
-
Hasumi H, Baba M, Hong SB, Hasumi Y, Huang Y, et al. (2008) Identification and characterization of a novel folliculin-interacting protein FNIP2. Gene 415: 60-67.
-
(2008)
Gene
, vol.415
, pp. 60-67
-
-
Hasumi, H.1
Baba, M.2
Hong, S.B.3
Hasumi, Y.4
Huang, Y.5
-
20
-
-
51649122895
-
Interaction of folliculin (Birt-Hogg-Dube gene product) with a novel Fnip1-like (FnipL/Fnip2) protein
-
Takagi Y, Kobayashi T, Shiono M, Wang L, Piao X, et al. (2008) Interaction of folliculin (Birt-Hogg-Dube gene product) with a novel Fnip1-like (FnipL/Fnip2) protein. Oncogene 27: 5339-5347.
-
(2008)
Oncogene
, vol.27
, pp. 5339-5347
-
-
Takagi, Y.1
Kobayashi, T.2
Shiono, M.3
Wang, L.4
Piao, X.5
-
21
-
-
34548359242
-
The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe
-
van Slegtenhorst M, Khabibullin D, Hartman TR, Nicolas E, Kruger WD, et al. (2007) The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe. J Biol Chem 282: 24583-24590.
-
(2007)
J Biol Chem
, vol.282
, pp. 24583-24590
-
-
van Slegtenhorst, M.1
Khabibullin, D.2
Hartman, T.R.3
Nicolas, E.4
Kruger, W.D.5
-
22
-
-
84870204290
-
Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN
-
Hasumi H, Baba M, Hasumi Y, Huang Y, Oh H, et al. (2012) Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN. J Natl Cancer Inst 104: 1750-1764.
-
(2012)
J Natl Cancer Inst
, vol.104
, pp. 1750-1764
-
-
Hasumi, H.1
Baba, M.2
Hasumi, Y.3
Huang, Y.4
Oh, H.5
-
23
-
-
84883840386
-
Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines
-
Todaro GJ, Green H, (1963) Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol 17: 299-313.
-
(1963)
J Cell Biol
, vol.17
, pp. 299-313
-
-
Todaro, G.J.1
Green, H.2
-
24
-
-
41049102001
-
Preparation, culture, and immortalization of mouse embryonic fibroblasts
-
Chapter 28: Unit 28 21
-
Xu J (2005) Preparation, culture, and immortalization of mouse embryonic fibroblasts. Curr Protoc Mol Biol Chapter 28: Unit 28 21.
-
(2005)
Curr Protoc Mol Biol
-
-
Xu, J.1
-
25
-
-
57849147670
-
Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing
-
Zimmer M, Ebert BL, Neil C, Brenner K, Papaioannou I, et al. (2008) Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing. Mol Cell 32: 838-848.
-
(2008)
Mol Cell
, vol.32
, pp. 838-848
-
-
Zimmer, M.1
Ebert, B.L.2
Neil, C.3
Brenner, K.4
Papaioannou, I.5
-
26
-
-
0342463159
-
Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges
-
Danos O, Mulligan RC, (1988) Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proc Natl Acad Sci U S A 85: 6460-6464.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 6460-6464
-
-
Danos, O.1
Mulligan, R.C.2
-
27
-
-
47149115342
-
Mutation analysis of the FLCN gene in Chinese patients with sporadic and familial isolated primary spontaneous pneumothorax
-
Ren HZ, Zhu CC, Yang C, Chen SL, Xie J, et al. (2008) Mutation analysis of the FLCN gene in Chinese patients with sporadic and familial isolated primary spontaneous pneumothorax. Clin Genet 74: 178-183.
-
(2008)
Clin Genet
, vol.74
, pp. 178-183
-
-
Ren, H.Z.1
Zhu, C.C.2
Yang, C.3
Chen, S.L.4
Xie, J.5
-
28
-
-
33847034141
-
Novel mutations in the BHD gene and absence of loss of heterozygosity in fibrofolliculomas of Birt-Hogg-Dube patients
-
van Steensel MA, Verstraeten VL, Frank J, Kelleners-Smeets NW, Poblete-Gutierrez P, et al. (2007) Novel mutations in the BHD gene and absence of loss of heterozygosity in fibrofolliculomas of Birt-Hogg-Dube patients. J Invest Dermatol 127: 588-593.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 588-593
-
-
van Steensel, M.A.1
Verstraeten, V.L.2
Frank, J.3
Kelleners-Smeets, N.W.4
Poblete-Gutierrez, P.5
-
29
-
-
79960833877
-
Birt Hogg-Dube syndrome-associated FLCN mutations disrupt protein stability
-
Nahorski MS, Reiman A, Lim DH, Nookala RK, Seabra L, et al. (2011) Birt Hogg-Dube syndrome-associated FLCN mutations disrupt protein stability. Hum Mutat 32: 921-929.
-
(2011)
Hum Mutat
, vol.32
, pp. 921-929
-
-
Nahorski, M.S.1
Reiman, A.2
Lim, D.H.3
Nookala, R.K.4
Seabra, L.5
-
30
-
-
59649104851
-
Folliculin mutations are not associated with severe COPD
-
Cho MH, Klanderman BJ, Litonjua AA, Sparrow D, Silverman EK, et al. (2008) Folliculin mutations are not associated with severe COPD. BMC Med Genet 9: 120.
-
(2008)
BMC Med Genet
, vol.9
, pp. 120
-
-
Cho, M.H.1
Klanderman, B.J.2
Litonjua, A.A.3
Sparrow, D.4
Silverman, E.K.5
-
31
-
-
77957559053
-
Frameshift mutation hotspot identified in Smith-Magenis syndrome: case report and review of literature
-
Truong HT, Dudding T, Blanchard CL, Elsea SH, (2010) Frameshift mutation hotspot identified in Smith-Magenis syndrome: case report and review of literature. BMC Med Genet 11: 142.
-
(2010)
BMC Med Genet
, vol.11
, pp. 142
-
-
Truong, H.T.1
Dudding, T.2
Blanchard, C.L.3
Elsea, S.H.4
-
32
-
-
53249113792
-
Familial non-VHL clear cell (conventional) renal cell carcinoma: clinical features, segregation analysis, and mutation analysis of FLCN
-
Woodward ER, Ricketts C, Killick P, Gad S, Morris MR, et al. (2008) Familial non-VHL clear cell (conventional) renal cell carcinoma: clinical features, segregation analysis, and mutation analysis of FLCN. Clin Cancer Res 14: 5925-5930.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5925-5930
-
-
Woodward, E.R.1
Ricketts, C.2
Killick, P.3
Gad, S.4
Morris, M.R.5
-
33
-
-
0024429019
-
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
-
Chen PL, Scully P, Shew JY, Wang JY, Lee WH, (1989) Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell 58: 1193-1198.
-
(1989)
Cell
, vol.58
, pp. 1193-1198
-
-
Chen, P.L.1
Scully, P.2
Shew, J.Y.3
Wang, J.Y.4
Lee, W.H.5
-
34
-
-
0035085998
-
p53 Signaling and cell cycle checkpoints
-
Stewart ZA, Pietenpol JA, (2001) p53 Signaling and cell cycle checkpoints. Chem Res Toxicol 14: 243-263.
-
(2001)
Chem Res Toxicol
, vol.14
, pp. 243-263
-
-
Stewart, Z.A.1
Pietenpol, J.A.2
-
35
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA, (1995) The retinoblastoma protein and cell cycle control. Cell 81: 323-330.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
|