-
1
-
-
0345675905
-
A clinical survey of 1074 patients with asthma followed for two years
-
Rackemann FM A clinical survey of 1074 patients with asthma followed for two years. J Lab Clin Med 1927, 12:1185-1197.
-
(1927)
J Lab Clin Med
, vol.12
, pp. 1185-1197
-
-
Rackemann, F.M.1
-
2
-
-
33845478528
-
Multiple inflammatory hits and the pathogenesis of severe airway disease
-
Pavord ID, Birring SS, Berry M, Green RH, Brightling CE, Wardlaw AJ Multiple inflammatory hits and the pathogenesis of severe airway disease. Eur Respir J 2006, 27:884-888.
-
(2006)
Eur Respir J
, vol.27
, pp. 884-888
-
-
Pavord, I.D.1
Birring, S.S.2
Berry, M.3
Green, R.H.4
Brightling, C.E.5
Wardlaw, A.J.6
-
3
-
-
77950901497
-
Mepolizumab in refractory eosinophilic asthma
-
Pavord ID, Haldar P, Bradding P, Wardlaw AJ Mepolizumab in refractory eosinophilic asthma. Thorax 2010, 65:370.
-
(2010)
Thorax
, vol.65
, pp. 370
-
-
Pavord, I.D.1
Haldar, P.2
Bradding, P.3
Wardlaw, A.J.4
-
5
-
-
62549084077
-
A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma
-
Wenzel SE, Barnes PJ, Bleecker ER, et al. A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am J Respir Crit Care Med 2009, 179:549-558.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 549-558
-
-
Wenzel, S.E.1
Barnes, P.J.2
Bleecker, E.R.3
-
7
-
-
76149146032
-
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program
-
Moore WC, Meyers DA, Wenzel SE, et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 2010, 181:315-323.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 315-323
-
-
Moore, W.C.1
Meyers, D.A.2
Wenzel, S.E.3
-
8
-
-
79954994400
-
Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes
-
Garcia-Aymerich J, Gomez FP, Benet M, et al. Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes. Thorax 2011, 66:430-437.
-
(2011)
Thorax
, vol.66
, pp. 430-437
-
-
Garcia-Aymerich, J.1
Gomez, F.P.2
Benet, M.3
-
9
-
-
0034526865
-
Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions
-
American Thoracic Society
-
Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions. Am J Respir Crit Care Med 2000, 162:2341-2351. American Thoracic Society.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 2341-2351
-
-
-
10
-
-
80052755474
-
Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial
-
Powell H, Murphy VE, Taylor DR, et al. Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial. Lancet 2011, 378:983-990.
-
(2011)
Lancet
, vol.378
, pp. 983-990
-
-
Powell, H.1
Murphy, V.E.2
Taylor, D.R.3
-
11
-
-
33344476409
-
Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations
-
Jayaram L, Pizzichini MM, Cook RJ, et al. Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations. Eur Respir J 2006, 27:483-494.
-
(2006)
Eur Respir J
, vol.27
, pp. 483-494
-
-
Jayaram, L.1
Pizzichini, M.M.2
Cook, R.J.3
-
12
-
-
0037202790
-
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial
-
Green RH, Brightling CE, McKenna S, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002, 360:1715-1721.
-
(2002)
Lancet
, vol.360
, pp. 1715-1721
-
-
Green, R.H.1
Brightling, C.E.2
McKenna, S.3
-
13
-
-
80052936263
-
Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers
-
Bafadhel M, McKenna S, Terry S, et al. Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers. Am J Respir Crit Care Med 2011, 184:662-671.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 662-671
-
-
Bafadhel, M.1
McKenna, S.2
Terry, S.3
-
14
-
-
0034727453
-
Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial
-
Brightling CE, Monteiro W, Ward R, et al. Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2000, 356:1480-1485.
-
(2000)
Lancet
, vol.356
, pp. 1480-1485
-
-
Brightling, C.E.1
Monteiro, W.2
Ward, R.3
-
15
-
-
34248206610
-
Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial
-
Siva R, Green RH, Brightling CE, et al. Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial. Eur Respir J 2007, 29:906-913.
-
(2007)
Eur Respir J
, vol.29
, pp. 906-913
-
-
Siva, R.1
Green, R.H.2
Brightling, C.E.3
-
17
-
-
42149110813
-
Management of chronic cough
-
Pavord ID, Chung KF Management of chronic cough. Lancet 2008, 371:1375-1384.
-
(2008)
Lancet
, vol.371
, pp. 1375-1384
-
-
Pavord, I.D.1
Chung, K.F.2
-
18
-
-
34047099762
-
Asthma control during the year after bronchial thermoplasty
-
Cox G, Thomson NC, Rubin AS, et al. Asthma control during the year after bronchial thermoplasty. N Engl J Med 2007, 356:1327-1337.
-
(2007)
N Engl J Med
, vol.356
, pp. 1327-1337
-
-
Cox, G.1
Thomson, N.C.2
Rubin, A.S.3
-
19
-
-
0038075468
-
A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema
-
Fishman A, Martinez F, Naunheim K, et al. A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema. N Engl J Med 2003, 348:2059-2073.
-
(2003)
N Engl J Med
, vol.348
, pp. 2059-2073
-
-
Fishman, A.1
Martinez, F.2
Naunheim, K.3
-
20
-
-
0035684297
-
Smoking and airway inflammation in patients with mild asthma
-
Chalmers GW, MacLeod KJ, Thomson L, Little SA, McSharry C, Thomson NC Smoking and airway inflammation in patients with mild asthma. Chest 2001, 120:1917-1922.
-
(2001)
Chest
, vol.120
, pp. 1917-1922
-
-
Chalmers, G.W.1
MacLeod, K.J.2
Thomson, L.3
Little, S.A.4
McSharry, C.5
Thomson, N.C.6
-
21
-
-
0032798777
-
Eosinophilic bronchitis is an important cause of chronic cough
-
Brightling CE, Ward R, Goh KL, Wardlaw AJ, Pavord ID Eosinophilic bronchitis is an important cause of chronic cough. Am J Respir Crit Care Med 1999, 160:406-410.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 406-410
-
-
Brightling, C.E.1
Ward, R.2
Goh, K.L.3
Wardlaw, A.J.4
Pavord, I.D.5
-
22
-
-
0023200791
-
Angiotensin-converting enzyme and the cough reflex
-
Morice AH, Lowry R, Brown MJ, Higenbottam T Angiotensin-converting enzyme and the cough reflex. Lancet 1987, 330:1116-1118.
-
(1987)
Lancet
, vol.330
, pp. 1116-1118
-
-
Morice, A.H.1
Lowry, R.2
Brown, M.J.3
Higenbottam, T.4
-
23
-
-
37849028688
-
Poor adherence with inhaled corticosteroids for asthma: can using a single inhaler containing budesonide and formoterol help?
-
Sovani MP, Whale CI, Oborne J, et al. Poor adherence with inhaled corticosteroids for asthma: can using a single inhaler containing budesonide and formoterol help?. Br J Gen Pract 2008, 58:37-43.
-
(2008)
Br J Gen Pract
, vol.58
, pp. 37-43
-
-
Sovani, M.P.1
Whale, C.I.2
Oborne, J.3
-
24
-
-
78649874113
-
IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma
-
Fairs A, Agbetile J, Hargadon B, et al. IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma. Am J Respir Crit Care Med 2010, 182:1362-1368.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 1362-1368
-
-
Fairs, A.1
Agbetile, J.2
Hargadon, B.3
-
25
-
-
4444232912
-
Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma
-
Djukanovic R, Wilson SJ, Kraft M, et al. Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med 2004, 170:583-593.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 583-593
-
-
Djukanovic, R.1
Wilson, S.J.2
Kraft, M.3
-
26
-
-
0038752563
-
Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: a randomized controlled trial
-
Wark PA, Hensley MJ, Saltos N, et al. Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: a randomized controlled trial. J Allergy Clin Immunol 2003, 111:952-957.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 952-957
-
-
Wark, P.A.1
Hensley, M.J.2
Saltos, N.3
-
27
-
-
79959796818
-
Anti-IgE for asthma in inner-city children
-
Busse W, Gergen PJ, Calatroni A Anti-IgE for asthma in inner-city children. N Engl J Med 2011, 364:2557-2558.
-
(2011)
N Engl J Med
, vol.364
, pp. 2557-2558
-
-
Busse, W.1
Gergen, P.J.2
Calatroni, A.3
-
28
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, Brightling CE, Hargadon B, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009, 360:973-984.
-
(2009)
N Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
-
29
-
-
84865145614
-
Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial
-
Pavord ID, Korn S, Howarth P, et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet 2012, 380:651-659.
-
(2012)
Lancet
, vol.380
, pp. 651-659
-
-
Pavord, I.D.1
Korn, S.2
Howarth, P.3
-
30
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
Nair P, Pizzichini MM, Kjarsgaard M, et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009, 360:985-993.
-
(2009)
N Engl J Med
, vol.360
, pp. 985-993
-
-
Nair, P.1
Pizzichini, M.M.2
Kjarsgaard, M.3
-
31
-
-
0030869812
-
Erythromycin and diffuse panbronchiolitis
-
Koyama H, Geddes DM Erythromycin and diffuse panbronchiolitis. Thorax 1997, 52:915-918.
-
(1997)
Thorax
, vol.52
, pp. 915-918
-
-
Koyama, H.1
Geddes, D.M.2
-
32
-
-
38348998987
-
Clarithromycin targets neutrophilic airway inflammation in refractory asthma
-
Simpson JL, Powell H, Boyle MJ, Scott RJ, Gibson PG Clarithromycin targets neutrophilic airway inflammation in refractory asthma. Am J Respir Crit Care Med 2008, 177:148-155.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 148-155
-
-
Simpson, J.L.1
Powell, H.2
Boyle, M.J.3
Scott, R.J.4
Gibson, P.G.5
-
33
-
-
80052157895
-
Azithromycin for prevention of exacerbations of COPD
-
Albert RK, Connett J, Bailey WC, et al. Azithromycin for prevention of exacerbations of COPD. N Engl J Med 2011, 365:689-698.
-
(2011)
N Engl J Med
, vol.365
, pp. 689-698
-
-
Albert, R.K.1
Connett, J.2
Bailey, W.C.3
-
34
-
-
12944257305
-
The influence of smoking on the treatment response in patients with asthma
-
Thomson NC, Spears M The influence of smoking on the treatment response in patients with asthma. Curr Opin Allergy Clin Immunol 2005, 5:57-63.
-
(2005)
Curr Opin Allergy Clin Immunol
, vol.5
, pp. 57-63
-
-
Thomson, N.C.1
Spears, M.2
-
36
-
-
0030067771
-
A cross sectional study of the independent effect of occupation on lung function in British coal miners
-
Lewis S, Bennett J, Richards K, Britton J A cross sectional study of the independent effect of occupation on lung function in British coal miners. Occup Environ Med 1996, 53:125-128.
-
(1996)
Occup Environ Med
, vol.53
, pp. 125-128
-
-
Lewis, S.1
Bennett, J.2
Richards, K.3
Britton, J.4
-
37
-
-
0037114196
-
Living near a main road and the risk of wheezing illness in children
-
Venn AJ, Lewis SA, Cooper M, Hubbard R, Britton J Living near a main road and the risk of wheezing illness in children. Am J Respir Crit Care Med 2001, 164:2177-2180.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 2177-2180
-
-
Venn, A.J.1
Lewis, S.A.2
Cooper, M.3
Hubbard, R.4
Britton, J.5
-
38
-
-
0034904034
-
Endotoxin-stimulated innate immunity: a contributing factor for asthma
-
Reed CE, Milton DK Endotoxin-stimulated innate immunity: a contributing factor for asthma. J Allergy Clin Immunol 2001, 108:157-166.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 157-166
-
-
Reed, C.E.1
Milton, D.K.2
-
39
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004, 350:2645-2653.
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
-
40
-
-
0037335979
-
Is asthma an infectious disease?
-
Lemanski RJ Is asthma an infectious disease?. Chest 2003, 123(suppl 3):385S-390S.
-
(2003)
Chest
, vol.123
, Issue.SUPPL. 3
-
-
Lemanski, R.J.1
-
41
-
-
0037108414
-
Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers: a descriptive study
-
Birring SS, Brightling CE, Bradding P, et al. Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers: a descriptive study. Am J Respir Crit Care Med 2002, 166:1078-1083.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 1078-1083
-
-
Birring, S.S.1
Brightling, C.E.2
Bradding, P.3
-
42
-
-
14944351482
-
Airway function and markers of airway inflammation in patients with treated hypothyroidism
-
Birring SS, Patel RB, Parker D, et al. Airway function and markers of airway inflammation in patients with treated hypothyroidism. Thorax 2005, 60:249-253.
-
(2005)
Thorax
, vol.60
, pp. 249-253
-
-
Birring, S.S.1
Patel, R.B.2
Parker, D.3
-
43
-
-
0033965020
-
The lung in inflammatory bowel disease
-
Camus P, Colby TV The lung in inflammatory bowel disease. Eur Respir J 2000, 15:5-10.
-
(2000)
Eur Respir J
, vol.15
, pp. 5-10
-
-
Camus, P.1
Colby, T.V.2
-
44
-
-
0037331154
-
Interferon therapy induces the improvement of lung function by inhaled corticosteroid therapy in asthmatic patients with chronic hepatitis C virus infection: a preliminary study
-
Kanazawa H, Mamoto T, Hirata K, Yoshikawa J Interferon therapy induces the improvement of lung function by inhaled corticosteroid therapy in asthmatic patients with chronic hepatitis C virus infection: a preliminary study. Chest 2003, 123:600-603.
-
(2003)
Chest
, vol.123
, pp. 600-603
-
-
Kanazawa, H.1
Mamoto, T.2
Hirata, K.3
Yoshikawa, J.4
-
45
-
-
0037331861
-
Accelerated decline of lung function in COPD patients with chronic hepatitis C virus infection: a preliminary study based on small numbers of patients
-
Kanazawa H, Hirata K, Yoshikawa J Accelerated decline of lung function in COPD patients with chronic hepatitis C virus infection: a preliminary study based on small numbers of patients. Chest 2003, 123:596-599.
-
(2003)
Chest
, vol.123
, pp. 596-599
-
-
Kanazawa, H.1
Hirata, K.2
Yoshikawa, J.3
-
47
-
-
0141887302
-
Hypothesis: Does COPD have an autoimmune component?
-
Agusti A, MacNee W, Donaldson K, Cosio M Hypothesis: Does COPD have an autoimmune component?. Thorax 2003, 58:832-834.
-
(2003)
Thorax
, vol.58
, pp. 832-834
-
-
Agusti, A.1
MacNee, W.2
Donaldson, K.3
Cosio, M.4
-
48
-
-
33745742455
-
Effects of smoking cessation on lung function and airway inflammation in smokers with asthma
-
Chaudhuri R, Livingston E, McMahon AD, et al. Effects of smoking cessation on lung function and airway inflammation in smokers with asthma. Am J Respir Crit Care Med 2006, 174:127-133.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 127-133
-
-
Chaudhuri, R.1
Livingston, E.2
McMahon, A.D.3
-
49
-
-
0027962628
-
Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study
-
Anthonisen NR, Connett JE, Kiley JP, et al. Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study. JAMA 1994, 272:1497-1505.
-
(1994)
JAMA
, vol.272
, pp. 1497-1505
-
-
Anthonisen, N.R.1
Connett, J.E.2
Kiley, J.P.3
-
50
-
-
0027322797
-
Occupational dust exposure and chronic obstructive pulmonary disease. A systematic overview of the evidence
-
Oxman AD, Muir DC, Shannon HS, Stock SR, Hnizdo E, Lange HJ Occupational dust exposure and chronic obstructive pulmonary disease. A systematic overview of the evidence. Am Rev Respir Dis 1993, 148:38-48.
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 38-48
-
-
Oxman, A.D.1
Muir, D.C.2
Shannon, H.S.3
Stock, S.R.4
Hnizdo, E.5
Lange, H.J.6
-
51
-
-
58349115630
-
Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: the Fungal Asthma Sensitization Trial (FAST) study
-
Denning DW, O'Driscoll BR, Powell G, et al. Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: the Fungal Asthma Sensitization Trial (FAST) study. Am J Respir Crit Care Med 2009, 179:11-18.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 11-18
-
-
Denning, D.W.1
O'Driscoll, B.R.2
Powell, G.3
-
52
-
-
32644490529
-
Evidence of a role of tumor necrosis factor alpha in refractory asthma
-
Berry MA, Hargadon B, Shelley M, et al. Evidence of a role of tumor necrosis factor alpha in refractory asthma. N Engl J Med 2006, 354:697-708.
-
(2006)
N Engl J Med
, vol.354
, pp. 697-708
-
-
Berry, M.A.1
Hargadon, B.2
Shelley, M.3
-
53
-
-
28244479315
-
Tumour necrosis factor (TNFalpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma
-
Howarth PH, Babu KS, Arshad HS, et al. Tumour necrosis factor (TNFalpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma. Thorax 2005, 60:1012-1018.
-
(2005)
Thorax
, vol.60
, pp. 1012-1018
-
-
Howarth, P.H.1
Babu, K.S.2
Arshad, H.S.3
-
54
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
Leckie MJ, ten Brinke A, Khan J, et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 2000, 356:2144-2148.
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
ten Brinke, A.2
Khan, J.3
-
55
-
-
36749065556
-
A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma
-
Flood-Page P, Swenson C, Faiferman I, et al. A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma. Am J Respir Crit Care Med 2007, 176:1062-1071.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 1062-1071
-
-
Flood-Page, P.1
Swenson, C.2
Faiferman, I.3
-
56
-
-
33750094661
-
COPD: an inhaled corticosteroid-resistant, oral corticosteroid-responsive condition
-
Saha S, Siva R, Brightling CE, Pavord ID COPD: an inhaled corticosteroid-resistant, oral corticosteroid-responsive condition. Eur Respir J 2006, 27:863-865.
-
(2006)
Eur Respir J
, vol.27
, pp. 863-865
-
-
Saha, S.1
Siva, R.2
Brightling, C.E.3
Pavord, I.D.4
|