Cognition-emotion interactions in schizophrenia: Emerging evidence on working memory load and implicit facial-affective processing

Cognition and Emotion

Volumn 27, Issue 5, 2013, Pages 875-899

  Mano, Quintino R ^a,b   Brown, Gregory G ^a,b  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Emotion; Psychosocial functioning; Schizophrenia; Working memory

Indexed keywords

AMYGDALOID NUCLEUS; ARTICLE; ATTENTION; BASAL GANGLION; COGNITION; ELECTROENCEPHALOGRAM; EMOTION; FACIAL EXPRESSION; HIPPOCAMPUS; HUMAN; INSULA; LEARNING; META ANALYSIS (TOPIC); MIDDLE FRONTAL GYRUS; NEUROIMAGING; NEUROPHYSIOLOGY; NEUROSCIENCE; PERSONAL EXPERIENCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; SCHIZOPHRENIA; SOCIAL INTERACTION; SOCIAL ISOLATION; SOCIAL LEARNING; SOCIAL PSYCHOLOGY; SUPERIOR FRONTAL GYRUS; VISUAL MEMORY; WISCONSIN CARD SORTING TEST; WORKING MEMORY;

AFFECT; COGNITION; EMOTIONS; FACIAL EXPRESSION; HUMANS; MEMORY, SHORT-TERM; NEUROIMAGING; NEUROPSYCHOLOGICAL TESTS; PREFRONTAL CORTEX; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 84880040525     PISSN: 02699931     EISSN: 14640600     Source Type: Journal    
DOI: 10.1080/02699931.2012.751360     Document Type: Article

References (133)

1. Addington, J., Saeedi, H. and Addington, D. 2006a. Influence of social perception and social knowledge on cognitive and social functioning in early psychosis. British Journal of Psychiatry, 189: 373-378. doi: 10.1192/bjp.bp.105.021022
2. Addington, J., Saeedi, H. and Addington, D. 2006b. Facial affect recognition: A mediator between cognitive and social functioning in psychosis?. Schizophrenia Research, 85: 142-150. doi: 10.1016/j.schres.2006.03.028
3. Adolphs, R. 2001. The neurobiology of social cognition. Current Opinion in Neurobiology, 11: 231-239. doi: 10.1016/S0959-4388(00)00202-6
4. Anticevic, A., Repovs, G., Corlett, P. R. and Barch, D. M. 2011. Negative and nonemotional interference with visual working memory in schizophrenia. Biological Psychiatry, 70 (12): 1159-1168. doi: 10.1016/j.biopsych.2011.07.010
5. Anticevic, A., Van Snellenberg, J. X., Cohen, R. E., Repovs, G., Dowd, E. C., & Barch, D. M. 2012. Amygdala recruitment in schizophrenia in response to aversive emotional material: A meta-analysis of neuroimaging studies. Schizophrenia Bulletin, 38 (3), 608-621.
6. Arce, E., Simmons, A. N., Stein, M. B., Winkielman, P., Hitchcock, C. and Paulus, M. P. 2009. Association between individual differences in self-reported emotional resilience and the affective perception of neutral faces. Journal of Affective Disorders, 114: 286-293. doi: 10.1016/j.jad.2008.08.015
7. Baddeley, A. 2003. Working memory: Looking back and looking forward. Nature Reviews: Neuroscience, 4: 829-839. doi: 10.1038/nrn1201
8. Bargh, J. A. 1989. " Conditional automaticity: Varieties of automatic influence in social perception and cognition ". In Unintended thought, Edited by: Uleman, J. S. and Bargh, J. A. 3-51. New York: Guilford Press.
9. Becerril, K. and Barch, D. 2010. Influence of emotional processing on working memory in schizophrenia. Schizophrenia Bulletin, 37 (5): 1027-1038. doi: 10.1093/schbul/sbq009
10. Bledowski, C., Kaiser, J., & Rahm, B. (2010). Basic operations in working memory: Contributions from functional imaging studies. Behavioural Brain Research, 214 2, 172-179.
11. Bluhm, R. L., Miller, J., Lanius, R. A., Osuch, E. A., Boksman, K. Neufeld, R. 2007. Spontaneous low-frequency fluctuations in the BOLD signal in schizophrenia patients: Anomalies in the default network. Schizophrenia Bulletin, 33: 1004-1012. doi: 10.1093/schbul/sbm052
12. Braver, T. S., Cohen, J. D., Nystrom, L. E., Jonides, J., Smith, E. E. and Noll, D. C. 1997. A parametric study of prefrontal cortex involvement in human working memory. NeuroImage, 5: 49-62. doi: 10.1006/nimg.1996.0247
13. Brekke, J. S., Hoe, M., Long, J. and Green, M. F. 2007. How neurocognition and social cognition influence functional change during community-based psychosocial rehabilitation for individuals with schizophrenia. Schizophrenia Bulletin, 33: 1247-1256. doi: 10.1093/schbul/sbl072
14. Brekke, J. S., Kay, D. D., Kee, K. S. and Green, M. F. 2005. Biosocial pathways to functional outcome in schizophrenia. Schizophrenia Research, 80: 213-225. doi: 10.1016/j.schres.2005.07.008
15. Buss, A. and Lang, P. 1965. Psychological deficit in schizophrenia. Journal of Abnormal Psychology, 70: 2-24. doi: 10.1037/h0021685
16. Callicott, J. H., Bertolino, A., Mattay, V. S., Langheim, F. J. P., Duyn, J. Coppola, R. 2000. Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited. Cerebral Cortex, 10: 1078-1092. doi: 10.1093/cercor/10.11.1078
17. Callicott, J. H., Mattay, V. S., Bertolino, A., Finn, K., Coppola, R. Frank, J. A. 1999. Physiological characteristics of capacity constraints in working memory as revealed by functional MRI. Cerebral Cortex, 9: 20-26. doi: 10.1093/cercor/9.1.20
18. Callicott, J. H., Mattay, V. S., Verchiniski, B. A., Marenco, S., Egan, M. F. and Weinberger, D. R. 2003. Complexity of prefrontal cortical dysfunction in schizophrenia: More than up or down. American Journal of Psychiatry, 160 (12): 2209-2215. doi: 10.1176/appi.ajp.160.12.2209
19. Chan, R. C. K., Li, H., Cheung, E. F. C. and Gong, Q.-Y. 2010. Impaired facial emotion perception in schizophrenia: A meta-analysis. Psychiatry Research, 178: 381-390. doi: 10.1016/j.psychres.2009.03.035
20. Cohen, A. S. and Minor, K. S. 2010. Emotional experience in patients with schizophrenia revisited: Meta-analysis of laboratory studies. Schizophrenia Bulletin, 36 (1): 143-150. doi: 10.1093/schbul/sbn061
21. Cohen, A. S., Najolia, G. M., Brown, L. A. and Minor, K. S. 2011. The state-trait disjunction of anhedonia in schizophrenia: Potential affective, cognitive and social-based mechanism. Clinical Psychology Review, 31: 440-448. doi: 10.1016/j.cpr.2010.11.001
22. D'Esposito, M., Postle, B. R., Ballard, D. and Lease, J. 1999. Maintenance versus manipulation of information held in working memory: An event-related fMRI study. Brain and Cognition, 41: 66-86. doi: 10.1006/brcg.1999.1096
23. Diaz, M. T., He, G., Gadde, S., Bellion, C., Belger, A. Voyvodic, J. T. 2011. The influence of emotional distraction on verbal working memory: An fMRI investigation of comparing individuals with schizophrenia and healthy adults. Journal of Psychiatry Research, 45: 1184-1193. doi: 10.1016/j.jpsychires.2011.02.008
24. Dickinson, D., Ramsey, M. E. and Gold, J. M. 2007. Overlooking the obvious: A meta-analytic comparison of digit symbol coding tasks and other cognitive measures in schizophrenia. Archives of General Psychiatry, 64 (5): 532-542. doi: 10.1001/archpsyc.64.5.532
25. Dijksterhuis, A. and Aarts, H. 2003. On wildebeests and humans: The preferential detection of negative stimuli. Psychological Science, 14: 14-18. doi: 10.1111/1467-9280.t01-1-01412
26. Dolcos, F., Kragel, P., Wang, L. and McCarthy, G. 2006. Role of the inferior frontal cortex in coping with distracting emotions. NeuroReport, 17 (15): 1591-1594. doi: 10.1097/01.wnr.0000236860.24081.be
27. Dolcos, F. and McCarthy, G. 2006. Brain systems mediating cognitive interference by emotional distraction. The Journal of Neuroscience, 27 (6): 2072-2079. doi: 10.1523/JNEUROSCI.5042-05.2006
28. Dougherty, P. E., Bartlett, E. S. and Izard, C. E. 1974. Responses of schizophrenics to expressions of fundamental emotions. Journal of Clinical Psychology, 30: 243-246. doi: 10.1002/1097-4679(197407)30:3%WC243::AID-JCLP2270300304%WE3.0.CO;2-0
29. Eastwood, J. D., Smilek, D. and Merikle, P. M. 2001. Differential attentional guidance by unattended faces expressing positive and negative emotion. Perception & Psychophysics, 63: 1004-1013. doi: 10.3758/BF03194519
30. Ekman, P. and Cordaro, D. 2011. What is meant by calling emotions basic. Emotion Review, 3 (4): 364-370. doi: 10.1177/1754073911410740
31. Erber, R. and Tesser, A. 1992. Task effort and the regulation of mood: The absorption hypothesis. Journal of Experimental Social Psychology, 28: 339-359. doi: 10.1016/0022-1031(92)90050-T
32. Erthal, F. S., De Oliviera, L., Mocaiber, I., Pereira, M. G., Machado-Pinheiro, W. Volchan, E. 2005. Load-dependent modulation of affective picture processing. Cognitive, Affective, Behavioral Neuroscience, 5 (4): 388-395. doi: 10.3758/CABN.5.4.388
33. Flack, W. F., Laird, J. D., Cavallaro, L. A. and Miller, D. R. 1998. " Emotional expression and experience: A psychosocial perspective on schizophrenia ". In Emotions in psychopathology. Theory and research, Edited by: Flack, W. F. and Laird, J. D. 315-322. Oxford, UK: Oxford University Press.
34. Forbes, N. F., Carrick, L. A., McIntosh, A. M. and Lawrie, S. M. 2009. Working memory in schizophrenia: A meta-analysis. Psychological Medicine, 39: 889-905. doi: 10.1017/S0033291708004558
35. Freedman, R. 2003. Schizophrenia. New England Journal of Medicine, 349: 1738-1749. doi: 10.1056/NEJMra035458
36. Garrity, A. G., Pearlson, G. D., McKiernan, K., Lloyd, D., Kiehl, K. A. and Calhoun, V. D. 2007. Aberrant "default mode" functional connectivity in schizophrenia. American Journal of Psychiatry, 164: 450-457. doi: 10.1176/appi.ajp.164.3.450
37. Glahn, D. C., Ragland, J. D., Abramoff, A., Barett, J., Laird, A. R. Bearden, C. E. 2005. Beyond hypofrontality: A quantitative meta-analysis of functional neuroimaging studies of working memory in schizophrenia. Human Brain Mapping, 25 (1): 60-69. doi: 10.1002/hbm.20138
38. Goldberg, T. E., Berman, K. F., Fleming, K., Ostrem, J., Van Horn, J. D. Esposito, G. 1998. Uncoupling cognitive workload and prefrontal cortical physiology: A PET rCBF study. NeuroImage, 7: 296-303. doi: 10.1006/nimg.1998.0338
39. Gottheil, E., Paredes, A., Exline, R. V. and Winkelmayer, R. 1970. Communication of affect in schizophrenia. Archives of General Psychiatry, 22: 439-444. doi: 10.1001/archpsyc.1970.01740290055007
40. Gottheil, E., Thornton, C. C. and Exline, R. V. 1976. Appropriate and background affect in facial displays of emotion comparison of schizophrenic and normal males. Archives of General Psychiatry, 33: 565-568. doi: 10.1001/archpsyc.1976.01770050033004
41. Granholm, E., Asarnow, R. F., Sarkin, A. J. and Dykes, K. L. 1996. Pupillary responses index cognitive resource limitations. Psychophysiology, 33: 457-461. doi: 10.1111/j.1469-8986.1996.tb01071.x
42. Green, M. F. 1996. What are the functional consequences of neurocognitive deficits in schizophrenia?. American Journal of Psychiatry, 153: 321-330.
43. Green, M. F., Kern, R. S. Braff, D. L. 2000. Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the right stuff?. Schizophrenia Bulletin, 26: 119-136. doi: 10.1093/oxfordjournals.schbul.a033430
44. Green, M. F., Kern, R. S. and Heaton, R. K. 2004. Longitudinal studies of cognition and functional outcome in schizophrenia: Implications for MATRICS. Schizophrenia Research, 72: 41-51. doi: 10.1016/j.schres.2004.09.009
45. Green, M. F., Lee, J., Cohen, M. S., Engel, S. A., Korb, A. S. Nuechterlein, K. H. 2009. Functional neuroanatomy of visual masking deficits in schizophrenia. Archives of General Psychiatry, 66 (12): 1295-1303. doi: 10.1001/archgenpsychiatry.2009.132
46. Gur, R. E., Loughead, J., Kohler, C. G., Elliott, M. A., Lesko, K. Ruparel, K. 2007. Limbic activation associated with misidentification of fearful faces and flat affect in schizophrenia. Archives of General Psychiatry, 64 (12): 1356-1366. doi: 10.1001/archpsyc.64.12.1356
47. Gur, R. E., McGrath, C., Chan, R. M., Schroeder, L., Turner, T. Turetsky, B. I. 2002. An fMRI study of facial emotion processing in patients with schizophrenia. American Journal of Psychiatry, 159: 1992-1999. doi: 10.1176/appi.ajp.159.12.1992
48. Habel, U., Krasenbrink, I., Bowi, U., Ott, G. and Schneider, F. 2006. A special role of negative emotion in children and adolescents with schizophrenia and other psychoses. Psychiatry Research, 145: 9-19. doi: 10.1016/j.psychres.2005.11.001
49. Hall, J., Whalley, H. C., McKirdy, J. W., Romaniuk, L., McGonigle, D. McIntosh, A. M. 2008. Over activation of fear systems to neutral faces in schizophrenia. Biological Psychiatry, 64: 70-73. doi: 10.1016/j.biopsych.2007.12.014
50. Herbener, E. S., Rosen, C., Khine, T. and Sweeney, A. 2007. Failure of positive but not negative emotional valence to enhance memory in schizophrenia. Journal of Abnormal Psychology, 116 (1): 43-55. doi: 10.1037/0021-843X.116.1.43
51. Herbener, E. S., Song, W., Khine, T. T. and Sweeney, J. A. 2008. What aspects of emotional functioning are impaired in schizophrenia?. Schizophrenia Research, 98 (1-3): 239-246. doi: 10.1016/j.schres.2007.06.025
52. Holt, D. J., Kunkel, L., Weiss, A. P., Goff, D. C., Wright, C. I. Shin, L. M. 2006. Increased medial temporal lobe activation during the passive viewing of emotional and neutral facial expressions in schizophrenia. Schizophrenia Research, 82: 153-162. doi: 10.1016/j.schres.2005.09.021
53. Holt, D. J., Weiss, A. P., Rauch, S. L., Wright, C. I., Zalesak, M. Goff, D. C. 2005. Sustained activation of the hippocampus in response to fearful faces in schizophrenia. Biological Psychiatry, 57: 1011-1019. doi: 10.1016/j.biopsych.2005.01.033
54. Honey, G. D., Bullmore, E. T. and Sharma, T. 2002. De-coupling of cognitive performance and cerebral functional response during working memory in schizophrenia. Schizophrenia Research, 53: 45-56. doi: 10.1016/S0920-9964(01)00154-2
55. Hooker, C. and Park, S. 2002. Emotion processing and its relationship to social functioning in schizophrenia patients. Psychiatry Research, 112: 41-50. doi: 10.1016/S0165-1781(02)00177-4
56. Hooker, C. I., Tully, L. M., Verosky, S. C., Fisher, M., Holland, C. and Vinogradov, S. 2011. Can I trust you? Negative affective priming influences social judgments in schizophrenia. Journal of Abnormal Psychology, 120 (1): 98-107. doi: 10.1037/a0020630
57. Hoschel, K. and Irle, E. 2001. Emotional priming of facial affect identification in schizophrenia. Schizophrenia Bulletin, 27 (2): 317-327. doi: 10.1093/oxfordjournals.schbul.a006877
58. Ihnen, G. H., Penn, D., Corrigan, P. and Martin, J. 1998. Social perception and social skill in schizophrenia. Psychiatry Research, 80 (3): 275-286. doi: 10.1016/S0165-1781(98)00079-1
59. Irani, F., Seligman, S., Kamath, V., Kohler, C., & Gur, R. C. 2012. A meta-analysis of emotion perception and functional outcomes in schizophrenia. Schizophrenia Research, 137, 203-211.
60. Jansma, J. M., Ramsey, N. F., van der Wee, N. J. A. and Kahn, R. S. 2004. Working memory capacity in schizophrenia: A parametric fMRI study. Schizophrenia Research, 68 (2): 159-171. doi: 10.1016/S0920-9964(03)00127-0
61. Jha, A. P. and McCarthy, G. 2000. The influence of memory load upon delay-interval activity in a working-memory task: An event-related functional MRI study. Journal of Cognitive Neuroscience, 12 (2): 90-105. doi: 10.1162/089892900564091
62. Kanske, P., Heissler, J., Schönfelder, S., Bongers, A. and Wessa, M. 2011. How to regulate emotion? Neural networks for reappraisal and distraction. Cerebral Cortex, 21 (6): 1379-1388. doi: 10.1093/cercor/bhq216
63. Kanwisher, N., McDermott, J. and Chun, M. M. 1997. The fusiform face area: A module in human extrastriate cortex specialized for face perception. The Journal of Neuroscience, 17 (11): 4302-4311.
64. Kapur, S. 2003. Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia. American Journal of Psychiatry, 160: 13-23. doi: 10.1176/appi.ajp.160.1.13
65. Karlsgodt, K. H., Sanz, J., van Erp, T. G. M., Bearden, C. E., Nuechterlein, K. H. and Cannon, T. D. 2009. Re-evaluating dorsolateral prefrontal cortex activation during working memory in schizophrenia. Schizophrenia Research, 108 (1-3): 143-150. doi: 10.1016/j.schres.2008.12.025
66. Kee, K. S., Green, M. F., Mintz, J. and Brekke, J. S. 2003. Is emotion processing a predictor of functional outcome in schizophrenia?. Schizophrenia Bulletin, 29 (3): 487-497. doi: 10.1093/oxfordjournals.schbul.a007021
67. Kellerman, T. S., Sternkopf, M. A., Schneider, F., Habel, U., Turetsky, B. I., Zilles, K., et al. 2012. Modulating the processing of emotional stimuli by cognitive demand. Social Cognitive and Affective Neuroscience, 7 (3), 263-273
68. Knudsen, E. I. 2007. Fundamental components of attention. Annual Review of Neuroscience, 30: 57-78. doi: 10.1146/annurev.neuro.30.051606.094256
69. Kock, K., Wagner, G., Nenadic, I., Schachtzabel, C., Schultz, C. Roebel, M. 2008. Fronto-striatal hypoactivation during correct information retrieval in patients with schizophrenia: An fMRI study. Neuroscience, 153 (1): 54-62. doi: 10.1016/j.neuroscience.2008.01.063
70. Kohler, C. G., Bilker, W., Haendoorn, M., Gur, R. E. and Gur, R. C. 2000. Emotion recognition deficit in schizophrenia: Association with symptomatology and cognition. Biological Psychiatry, 15: 127-136. doi: 10.1016/S0006-3223(00)00847-7
71. Kohler, C. G., Walker, J. B., Martin, E. A., Healey, K. M. and Moberg, P. J. 2010. Facial emotion perception in schizophrenia: A meta-analytic review. Schizophrenia Bulletin, 36 (5): 1009-1019. doi: 10.1093/schbul/sbn192
72. Kosaka, H., Omori, M., Murata, T., Lidaka, T., Yamada, H. Okada, T. 2002. Differential amygdala response during facial recognition in patients with schizophrenia: An fMRI study. Schizophrenia Research, 57 (1): 87-95. doi: 10.1016/S0920-9964(01)00324-3
73. Kring, A. M. and Caponigro, J. M. 2010. Emotion in schizophrenia: Where feeling meets thinking. Current Directions in Psychological Science, 19 (4): 255-259. doi: 10.1177/0963721410377599
74. Kring, A. M., Germans, G. M. and Gard, D. E. 2011. Emotion deficits in schizophrenia: Timing matters. Journal of Abnormal Psychology, 120 (1): 79-87. doi: 10.1037/a0021402
75. Kring, A. M. and Moran, E. K. 2008. Emotional response deficits in schizophrenia: Insights from affective science. Schizophrenia Bulletin, 34: 819-834. doi: 10.1093/schbul/sbn071
76. Kring, A. M. and Neale, J. M. 1996. Do schizophrenic patients show a disjunctive relationship among expressive, experiential, and psychophysiological components of emotion?. Journal of Abnormal Psychology, 105: 249-257. doi: 10.1037/0021-843X.105.2.249
77. Kucharska-Pietura, K., David, A. S., Masiak, M. and Phillips, M. L. 2005. Perception of facial and vocal affect by people with schizophrenia in early and late stages of illness. British Journal of Psychiatry, 187: 523-528. doi: 10.1192/bjp.187.6.523
78. Lavie, N. and De Fockert, J. 2005. The role of working memory in attentional capture. Psychonomic Bulletin & Review, 12: 669-674. doi: 10.3758/BF03196756
79. Lee, E., Kang, J. I., Park, I. H., Kim, J.-J. and An, S. K. 2008. Is a neutral face really evaluated as being emotionally neutral?. Psychiatry Research, 157: 77-85. doi: 10.1016/j.psychres.2007.02.005
80. Lee, J. and Park, S. 2005. Working memory impairment in schizophrenia: A meta-analysis. Journal of Abnormal Psychology, 114 (4): 599-611. doi: 10.1037/0021-843X.114.4.599
81. Li, H., Chan, R. C. K., McAlonan, G. M. and Gong, Q. 2010. Facial emotion processing in schizophrenia: A meta-analysis of functional neuroimaging data. Schizophrenia Bulletin, 36 (5): 1029-1039. doi: 10.1093/schbul/sbn190
82. Linden, S. C., Jackson, M. C., Subramanian, L., Wolf, C., Green, P. Healy, D. 2010. Emotion-cognition interactions in schizophrenia: Implicit and explicit effects of facial expression. Neuropsychologia, 48: 997-1002. doi: 10.1016/j.neuropsychologia.2009.11.023
83. Mandal, M. K. 1988. Affect related response in schizophrenia. Pharmacopsychoecologia, 28: 183-187.
84. Mandal, M. K., Pandey, R. and Prasad, A. B. 1998. Facial expressions of emotion and schizophrenia: A review. Schizophrenia Bulletin, 24: 339-412. doi: 10.1093/oxfordjournals.schbul.a033335
85. Mano, Q. R., Brown, G. G., Bolden, K., Aupperle, R., Paulus, M. P., & Stein, M. B. 2012. Curvilinear relationship between phonological working memory load and social-emotional modulation. Cognition and Emotion. (doi: 10.1080/02699931.2012.712948)
86. Manoach, D. S. 2003. Prefrontal cortex dysfunction during working memory performance in schizophrenia: Reconciling discrepant findings. Schizophrenia Research, 60: 285-298. doi: 10.1016/S0920-9964(02)00294-3
87. Manoach, D. S., Gollub, R. L., Benson, E. S., Searl, M. M., Goff, D. C. Halpern, E. 2000. Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance. Biological Psychiatry, 48: 99-109. doi: 10.1016/S0006-3223(00)00227-4
88. Mathews, J. R. and Barch, D. M. 2010. Emotion responsivity, social cognition, and functional outcome in schizophrenia. Journal of Abnormal Psychology, 119 (1): 50-59. doi: 10.1037/a0017861
89. Mednick, S. A. 1958. A learning theory approach to research on schizophrenia. Psychological Bulletin, 55: 316-327. doi: 10.1037/h0040425
90. Michalopoulou, P. G., Surguladze, S., Morley, L. A., Giampietro, V. P., Murray, R. M. and Shergill, S. S. 2008. Facial fear processing and psychotic symptoms in schizophrenia: Functional magnetic resonance imaging study. The British Journal of Psychiatry, 192: 191-196. doi: 10.1192/bjp.bp.106.032649
91. Minzenberg, M. J., Laird, A. R., Thelen, S., Carter, C. S. and Glahn, D. C. 2009. Meta-analysis of 41 functional neuroimaging studies of executive function in schizophrenia. Archives of General Psychiatry, 66 (8): 811-822. doi: 10.1001/archgenpsychiatry.2009.91
92. Muzekari, L. H. and Bates, M. E. 1977. Judgment of emotion among chronic schizophrenics. Journal of Clinical Psychology, 32: 662-666. doi: 10.1002/1097-4679(197707)33:3%WC662::AID-JCLP2270330312%WE3.0.CO;2-A
93. Okon-Singer, H., Tzelgov, J. and Henik, A. 2007. Distinguishing between automaticity and attention in the processing of emotionally significant stimuli. Emotion, 7 (1): 147-157. doi: 10.1037/1528-3542.7.1.147
94. Pauly, K., Seiferth, N. Y., Kellermann, T., Backes, V., Vloet, T. D. Shah, N. J. 2008. Cerebral dysfunctions of emotion-cognition interactions in adolescent-onset schizophrenia. Journal of American Academy of Child Adolescent Psychiatry, 47: 1299-1310. doi: 10.1097/CHI.0b013e318184ff16
95. Perlstein, W. M., Carter, C. S., Noll, D. C. and Cohen, J. D. 2001. Relation of prefrontal cortex dysfunction to working memory and symptoms in schizophrenia. American Journal of Psychiatry, 158: 1105-1113. doi: 10.1176/appi.ajp.158.7.1105
96. Pessoa, L., McKenna, M., Guitierrez, E. and Ungerleider, L. G. 2002. Neural processing of emotional faces requires attention. Proceedings of the National Academy of Sciences of the USA, 99: 11458-11463. doi: 10.1073/pnas.172403899
97. Pilowsky, I. and Bassett, D. 1980. Schizophrenia and the response to facial emotions. Comprehensive Psychiatry, 21: 236-244. doi: 10.1016/0010-440X(80)90008-5
98. Piskulic, D., Olver, J. S., Norman, T. R. and Maruff, P. 2007. Behavioral studies of spatial working dysfunction in schizophrenia: A qualitative literature review. Psychiatry Review, 150 (2): 111-121. doi: 10.1016/j.psychres.2006.03.018
99. Poole, J. H., Tobias, F. C. and Vinogradov, S. 2000. The functional relevance of affect recognition errors in schizophrenia. Journal of International Neuropsychological Society, 6 (6): 649-658. doi: 10.1017/S135561770066602X
100. Potkin, S. G., Turner, J. A., Brown, G. G., McCarthy, G., Greve, D. N. Glover, G. H. 2009. Working memory and DLPFC inefficiency in schizophrenia: The FBIRN study. Schizophrenia Bulletin, 133: 833-858.
101. Rauch, A. V., Reker, M., Ohrmann, P., Pedersen, A., Bauer, J. Dannlowski, U. 2010. Increased amygdala activation during automatic processing of facial emotion in schizophrenia. Psychiatry Research: Neuroimaging, 182: 200-206. doi: 10.1016/j.pscychresns.2010.03.005
102. Reichenberg, A. and Harvey, P. D. 2007. Neuropsychological impairments in schizophrenia: Integration of performance-based and brain imaging findings. Psychological Bulletin, 133 (5): 833-858. doi: 10.1037/0033-2909.133.5.833
103. Roux, P., Christophe, A. and Passerieux, C. 2010. The emotional paradox: Dissociation between explicit and implicit processing of emotional prosody in schizophrenia. Neuropsychologia, 48: 3642-3649. doi: 10.1016/j.neuropsychologia.2010.08.021
104. Russell, T. A., Reynaud, E., Kucharska-Pietura, K., Ecker, C., Benson, P. J. Zelaya, F. 2007. Neural responses to dynamic expressions of fear in schizophrenia. Neuropsychologia, 45 (1): 107-123. doi: 10.1016/j.neuropsychologia.2006.04.026
105. Rypma, B., Berger, J. S. and D'Esposito, M. 2002. The influence of working-memory demand and subject performance on prefrontal cortical activity. Journal of Cognitive Neuroscience, 14 (5): 721-731. doi: 10.1162/08989290260138627
106. Rypma, B. and D'Esposito, M. 1999. The roles of prefrontal brain regions in components of working memory: Effects of memory load and individual differences. Proceedings of the National Academy of Sciences of the USA, 96: 6558-6563. doi: 10.1073/pnas.96.11.6558
107. Rypma, B., Prabhakaran, V., Desmond, J. E., Glover, G. H. and Gabrieli, J. D. E. 1999. Load-dependent roles of frontal brain regions in the maintenance of working memory. NeuroImage, 9: 216-226. doi: 10.1006/nimg.1998.0404
108. Salgado-Pineda, P., Fakra, E., Delaveau, P., Hariri, A. and Blin, O. 2010. Differential patterns of initial and sustained responses in amygdala and cortical regions to emotional stimuli in schizophrenia patients and healthy participants. Journal of Psychiatry Neuroscience, 35 (1): 41-48. doi: 10.1503/jpn.090017
109. Schneider, F., Habel, U., Reske, M., Kellermann, T., Stöcker, T. Shah, N. J. 2007. Neural correlates of working memory dysfunction in first-episode schizophrenia patients: An fMRI multi-center study. Schizophrenia Research, 89 (1): 198-210. doi: 10.1016/j.schres.2006.07.021
110. Seiferth, N. Y., Pauly, K., Habel, U., Kellermann, T., Shah, N. J. Ruhrmann, S. 2008. Increased neural responses related to neutral faces in individuals at risk for psychosis. NeuroImage, 40 (1): 289-297. doi: 10.1016/j.neuroimage.2007.11.020
111. Sergi, M. and Green, M. F. 2003. Social perception and early visual processing in schizophrenia. Schizophrenia Research, 59 (2): 233-241. doi: 10.1016/S0920-9964(01)00405-4
112. Sparks, A., McDonald, S., Lino, B., O'Donnell, M. and Green, M. J. 2010. Social cognition, empathy and functional outcome in schizophrenia. Schizophrenia Research, 122: 172-178. doi: 10.1016/j.schres.2010.06.011
113. Srivastava, P. and Mandal, M. K. 1990. Proximal spacing to facial affect expressions in schizophrenia. Comprehensive Psychiatry, 31: 119-124. doi: 10.1016/0010-440X(90)90015-K
114. Strauss, G. P. and Herbener, E. S. 2011. Patterns of emotional experience in schizophrenia: Differences in emotional response to visual stimuli are associated with clinical presentation and functional outcome. Schizophrenia Research, 128: 117-123. doi: 10.1016/j.schres.2011.01.010
115. Surguladze, S., Russell, T., Kucharska-Pietura, K., Travis, M. J., Giampietro, V. David, A. S. 2006. A reversal of the normal pattern of parahippocampal response to neutral and fearful faces is associated with reality distortion in schizophrenia. Biological Psychiatry, 60 (5): 423-431. doi: 10.1016/j.biopsych.2005.11.021
116. Suslow, T., Droste, T., Roestel, C. and Arolt, V. 2003. Affective priming in schizophrenia with and without affective negative symptoms. European Archives of Psychiatry and Clinical Neuroscience, 253 (6): 292-300. doi: 10.1007/s00406-003-0443-4
117. Suslow, T., Roestel, C., Droste, T. and Arolt, V. 2003. Automatic processing of verbal emotion stimuli in schizophrenia. Psychiatry Research, 120: 131-144. doi: 10.1016/S0165-1781(03)00173-2
118. Taylor, S. F., Kang, J., Brege, I. S., Tso, I. F., Hosanangar, A. and Johnson, T. D. 2012. Meta-analysis of functional neuroimaging studies of emotion perception and experience in schizophrenia. Biological Psychiatry, 71 (2): 136-145. doi: 10.1016/j.biopsych.2011.09.007
119. Taylor, S. F., Luan Phan, K., Britton, J. C. and Liberzon, I. 2005. Neural responses to emotional salience in schizophrenia. Neuropsychopharmacology, 30: 984-995. doi: 10.1038/sj.npp.1300679
120. Thermenos, H., Goldstein, J. M., Buka, S. L., Poldrack, R. A., Koch, J. K. Tsuang, M. T. 2005. The effect of working memory performance on functional MRI in schizophrenia. Schizophrenia Research, 74 (2): 179-194. doi: 10.1016/j.schres.2004.07.021
121. Twamley, E. W., Palmer, B. W., Jeste, D. V., Taylor, M. J. and Heaton, R. K. 2006. Transient and executive function working memory in schizophrenia. Schizophrenia Research, 87: 185-190. doi: 10.1016/j.schres.2006.04.013
122. Tzelgov, J. 1997. Specifying the relations between automaticity and consciousness: A theoretical note. Consciousness and Cognition, 6: 441-451. doi: 10.1006/ccog.1997.0303
123. Ursu, S., Kring, A. M., Gard, M. G., Minzenberg, M. J., Yoon, J. H. Ragland, J. D. 2011. Prefrontal cortical deficits and impaired cognition-emotion interactions in schizophrenia. American Journal of Psychiatry, 168: 276-285. doi: 10.1176/appi.ajp.2010.09081215
124. Van Dillen, L. F., Heslenfeld, D. J. and Koole, S. L. 2009. Tuning down the emotional brain: An fMRI study of the effects of cognitive load on the processing of affective images. NeuroImage, 45: 1212-1219. doi: 10.1016/j.neuroimage.2009.01.016
125. Van Dillen, L. F. and Koole, S. L. 2007. Clearing the mind: A working memory model of distraction from negative feelings. Emotion, 7: 715-723. doi: 10.1037/1528-3542.7.4.715
126. Van Dillen, L. F. and Koole, S. L. 2009. How automatic is automatic vigilance? The role of working memory in attentional interference of negative information. Cognition and Emotion, 23 (6): 1106-1117. doi: 10.1080/02699930802338178
127. Van Snellenberg, J. X., Torres, I. J. and Thornton, A. E. 2006. Functional neuroimaging of working memory in schizophrenia: Task performance as a moderating variable. Neuropsychology, 20 (5): 497-510. doi: 10.1037/0894-4105.20.5.497
128. van't Wout, M., Aleman, A., Kessels, R. P. C., Cahn, W., de Haan, E. H. F. and Kahn, R. S. 2007. Exploring the nature of facial affect processing deficits in schizophrenia. Psychiatry Research, 150: 227-235. doi: 10.1016/j.psychres.2006.03.010
129. Walker, E. F., Marwit, S. J. and Emory, E. 1980. A cross-sectional study of emotion recognition in schizophrenics. Journal of Abnormal Psychology, 89: 428-436. doi: 10.1037/0021-843X.89.3.428
130. Whitfield-Gabrieli, S., Thermenos, H. W., Milanovic, S., Tsuang, M. T., Faraone, S. V. McCarley, R. W. 2009. Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proceedings of the National Academy of Sciences of the USA, 106 (4): 1279-1284. doi: 10.1073/pnas.0809141106
131. Williams, L. M., Das, P., Liddell, B. B., Olivieri, G., Skerrett, D. Phillips, M. L. 2004. Dysregulation of arousal and amygdala-prefrontal systems in paranoid schizophrenia. American Journal of Psychiatry, 161: 480-489. doi: 10.1176/appi.ajp.161.3.480
132. Yantis, S. 2000. Goal-directed and stimulus-driven determinants of attentional control. In S. Monsell & J. Driver, Attention and performance 18, pp. 73-103. Cambridge, MA: MIT Press.
133. Yoon, J. H., D'Esposito, M. and Carter, C. S. 2006. Preserved function of the fusiform face area in schizophrenia as revealed by fMRI. Psychiatry Research: Neuroimaging, 148 (2): 205-216. doi: 10.1016/j.pscychresns.2006.06.002