Enhancement of mitochondrial biogenesis with polyphenols: Combined effects of resveratrol and equol in human endothelial cells

Immunity and Ageing

Volumn 10, Issue 1, 2013, Pages

  Davinelli, Sergio ^a   Sapere, Nadia ^a   Visentin, Manuela ^b   Zella, Davide ^c   Scapagnini, Giovanni ^a  

^a UNIVERSITY OF MOLISE   (Italy)

^b Solvay Pharma SpA   (Italy)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EQUOL; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; POLYPHENOL; RESVERATROL; SIRTUIN 1; TRANSCRIPTION FACTOR NRF1;

ARTICLE; BIOGENESIS; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; UMBILICAL VEIN ENDOTHELIAL CELL;

EID: 84880017516     PISSN: None     EISSN: 17424933     Source Type: Journal    
DOI: 10.1186/1742-4933-10-28     Document Type: Article

References (28)

1. López-Lluch G, Irusta PM, Navas P, de Cabo R. Mitochondrial biogenesis and healthy aging. Exp Gerontol 2008, 43:813-819. 10.1016/j.exger.2008.06.014, 2562606, 18662766.
2. Hampel B, Malisan F, Niederegger H, Testi R, Jansen-Dürr P. Differential regulation of apoptotic cell death in senescent human cells. Exp Gerontol 2004, 39:1713-1721. 10.1016/j.exger.2004.05.010, 15582287.
3. Jendrach M, Pohl S, Vöth M, Kowald A, Hammerstein P, Bereiter-Hahn J. Morpho-dynamic changes of mitochondria during ageing of human endothelial cells. Mech Ageing Dev 2005, 126:813-821. 10.1016/j.mad.2005.03.002, 15888336.
4. Scarpulla RC. Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator. Ann N Y Acad Sci 2008, 1147:321-334. 10.1196/annals.1427.006, 2853241, 19076454.
5. Scarpulla RC. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol Rev 2008, 88:611-638. 10.1152/physrev.00025.2007, 18391175.
6. Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999, 98:115-124. 10.1016/S0092-8674(00)80611-X, 10412986.
7. Puigserver P, Spiegelman BM. Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr Rev 2003, 24:78-90. 10.1210/er.2002-0012, 12588810.
8. Kaufman BA, Durisic N, Mativetsky JM, Costantino S, Hancock MA, Grutter P, Shoubridge EA. The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures. Mol Biol Cell 2007, 18:3225-3236. 10.1091/mbc.E07-05-0404, 1951767, 17581862.
9. Aquilano K, Vigilanza P, Baldelli S, Pagliei B, Rotilio G, Ciriolo MR. Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis. J Biol Chem 2010, 285:21590-21599. 10.1074/jbc.M109.070169, 2898414, 20448046.
10. Prasain JK, Carlson SH, Wyss JM. Flavonoids and age-related disease: risk, benefits and critical windows. Maturitas 2010, 66:163-171. 10.1016/j.maturitas.2010.01.010, 2879453, 20181448.
11. Davinelli S, Di Marco R, Bracale R, Quattrone A, Zella D, Scapagnini G. Synergistic effect of L-Carnosine and EGCG in prevention of physiological brain aging. Curr Pharm Des 2012, 19:2722-2727.
12. Ferrari CK. Functional foods, herbs and nutraceuticals: towards biochemical mechanisms of healthy aging. Biogerontology 2004, 5:275-289. 10.1007/s10522-004-2566-z, 15547316.
13. Rüfer CE, Kulling SE. Antioxidant activity of isoflavones and their major metabolites using different in vitro assays. J Agric Food Chem 2006, 54:2926-2931. 10.1021/jf053112o, 16608210.
14. Ungvari Z, Sonntag WE, de Cabo R, Baur JA, Csiszar A. Mitochondrial protection by resveratrol. Exerc Sport Sci Rev 2011, 39:128-132. 10.1097/JES.0b013e3182141f80, 3123408, 21383627.
15. Grillari J, Hohenwarter O, Grabherr RM, Katinger H. Subtractive hybridization of mRNA from early passage and senescent endothelial cells. Exp Gerontol 2000, 35:187-197. 10.1016/S0531-5565(00)00080-2, 10767578.
16. Csiszar A, Labinskyy N, Pinto JT, Ballabh P, Zhang H, Losonczy G, Pearson K, de Cabo R, Pacher P, Zhang C, Ungvari Z. Resveratrol induces mitochondrial biogenesis in endothelial cells. Am J Physiol Heart Circ Physiol 2009, 297:H13-H20. 10.1152/ajpheart.00368.2009, 2711732, 19429820.
17. Kamiyama M, Kishimoto Y, Tani M, Utsunomiya K, Kondo K. Effects of equol on oxidized low-density lipoprotein-induced apoptosis in endothelial cells. J Atheroscler Thromb 2009, 16:239-249. 10.5551/jat.1057, 19638716.
18. Addabbo F, Ratliff B, Park HC, Kuo MC, Ungvari Z, Csiszar A, Krasnikov B, Sodhi K, Zhang F, Nasjletti A, Goligorsky MS. The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. Am J Pathol 2009, 174:34-43. 10.2353/ajpath.2009.080650, 2631316, 19095954.
19. Ferrara N, Rinaldi B, Corbi G, Conti V, Stiuso P, Boccuti S, Rengo G, Rossi F, Filippelli A. Exercise training promotes SIRT1 activity in aged rats. Rejuvenation Res 2008, 11:139-150. 10.1089/rej.2007.0576, 18069916.
20. Csaki C, Mobasheri A, Shakibaei M. Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis. Arthritis Res Ther 2009, 11:R165. 10.1186/ar2850, 3003513, 19889203.
21. Butow RA, Avadhani NG. Mitochondrial signaling: The retrograde response. Mol Cell 2004, 14:1-15. 10.1016/S1097-2765(04)00179-0, 15068799.
22. Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ. Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity. Biochim Biophys Acta 1822, 2012:753-783.
23. Calabrese EJ, Bachmann KA, Bailer AJ, et al. Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol 2007, 222:122-128. 10.1016/j.taap.2007.02.015, 17459441.
24. Tapia PC. Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients: " Mitohormesis" for health and vitality. Med Hypotheses 2006, 66:832-843. 10.1016/j.mehy.2005.09.009, 16242247.
25. Biswas G, Adebanjo OA, Freedman BD, Anandatheerthavarada HK, Vijayasarathy C, Zaidi M, Kotlikoff M, Avadhani NG. Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: A novel mode of inter-organelle crosstalk. EMBO J 1999, 18:522-533. 10.1093/emboj/18.3.522, 1171145, 9927412.
26. Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 2006, 127:1109-1122. 10.1016/j.cell.2006.11.013, 17112576.
27. Handschin C. The biology of PGC-1alpha and its therapeutic potential. Trends Pharmacol Sci 2009, 6:322-329.
28. Hock MB, Kralli A. Transcriptional control of mitochondrial biogenesis and function. Annu Rev Physiol 2009, 71:177-203. 10.1146/annurev.physiol.010908.163119, 19575678.