메뉴 건너뛰기




Volumn 43, Issue 7, 2013, Pages 1818-1827

Peripheral CD4+ T-cell tolerance is induced in vivo by rare antigen-bearing B cells in follicular, marginal zone, and B-1 subsets

Author keywords

B cell subsets; CD4+ T cells; Tolerance

Indexed keywords

B LYMPHOCYTE ANTIGEN;

EID: 84880013973     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242784     Document Type: Article
Times cited : (10)

References (58)
  • 2
    • 0022383875 scopus 로고
    • Role of membrane immunoglobulin (Ig) crosslinking in membrane Ig-mediated, major histocompatibility-restricted T cell-B cell cooperation
    • Tony, H.-P., Phillips, N. E. and Parker, D. C., Role of membrane immunoglobulin (Ig) crosslinking in membrane Ig-mediated, major histocompatibility-restricted T cell-B cell cooperation. J. Exp. Med. 1985. 162: 1695-1708.
    • (1985) J. Exp. Med. , vol.162 , pp. 1695-1708
    • Tony, H.-P.1    Phillips, N.E.2    Parker, D.C.3
  • 3
    • 0025240576 scopus 로고
    • Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes
    • Lanzavecchia, A., Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes. Annu. Rev. Immunol. 1990. 8: 773-793.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 773-793
    • Lanzavecchia, A.1
  • 4
    • 33644848385 scopus 로고    scopus 로고
    • Primary T cell expansion and differentiation in vivo requires antigen presentation by B cells
    • Crawford, A., Macleod, M., Schumacher, T., Corlett, L. and Gray, D., Primary T cell expansion and differentiation in vivo requires antigen presentation by B cells. J. Immunol. 2006. 176: 3498-3506.
    • (2006) J. Immunol. , vol.176 , pp. 3498-3506
    • Crawford, A.1    Macleod, M.2    Schumacher, T.3    Corlett, L.4    Gray, D.5
  • 5
    • 0035988252 scopus 로고    scopus 로고
    • Critical role of B cells in the development of T cell tolerance to aeroallergens
    • Tsitoura, D. C., Yeung, V. P., DeKruyff, R. H. and Umetsu, D. T., Critical role of B cells in the development of T cell tolerance to aeroallergens. Int. Immunol. 2002. 14: 659-667.
    • (2002) Int. Immunol. , vol.14 , pp. 659-667
    • Tsitoura, D.C.1    Yeung, V.P.2    DeKruyff, R.H.3    Umetsu, D.T.4
  • 6
    • 0035959006 scopus 로고    scopus 로고
    • A role for TGFbeta and B cells in immunologic tolerance after intravenous injection of soluble antigen
    • Valujskikh, A., VanBuskirk, A. M., Orosz, C. G. and Heeger, P. S., A role for TGFbeta and B cells in immunologic tolerance after intravenous injection of soluble antigen. Transplantation 2001. 72: 685-693.
    • (2001) Transplantation , vol.72 , pp. 685-693
    • Valujskikh, A.1    VanBuskirk, A.M.2    Orosz, C.G.3    Heeger, P.S.4
  • 7
    • 33646474975 scopus 로고    scopus 로고
    • Peripheral tolerance via the anterior chamber of the eye: role of B cells in MHC class I and II antigen presentation
    • Ashour, H. M. and Niederkorn, J. Y., Peripheral tolerance via the anterior chamber of the eye: role of B cells in MHC class I and II antigen presentation. J. Immunol. 2006. 176: 5950-5957.
    • (2006) J. Immunol. , vol.176 , pp. 5950-5957
    • Ashour, H.M.1    Niederkorn, J.Y.2
  • 9
    • 78650600361 scopus 로고    scopus 로고
    • The double life of a B-1 cell: self-reactivity selects for protective effector functions
    • Baumgarth, N., The double life of a B-1 cell: self-reactivity selects for protective effector functions. Nat. Rev. Immunol. 2011. 11: 34-46.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 34-46
    • Baumgarth, N.1
  • 10
    • 41649097373 scopus 로고    scopus 로고
    • Siglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activation
    • Ding, C., Liu, Y., Wang, Y., Park, B. K., Wang, C. Y., Zheng, P. and Liu, Y., Siglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activation. PLoS One 2007. 2: e997.
    • (2007) PLoS One , vol.2
    • Ding, C.1    Liu, Y.2    Wang, Y.3    Park, B.K.4    Wang, C.Y.5    Zheng, P.6    Liu, Y.7
  • 12
    • 0031053838 scopus 로고    scopus 로고
    • Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone
    • Chen, X., Martin, F., Forbush, K. A., Perlmutter, R. M. and Kearney, J. F., Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone. Int. Immunol. 1997. 9: 27-41.
    • (1997) Int. Immunol. , vol.9 , pp. 27-41
    • Chen, X.1    Martin, F.2    Forbush, K.A.3    Perlmutter, R.M.4    Kearney, J.F.5
  • 14
    • 0033563309 scopus 로고    scopus 로고
    • high CD21 high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells
    • high CD21 high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells. J. Immunol. 1999. 162: 7198-7207.
    • (1999) J. Immunol. , vol.162 , pp. 7198-7207
    • Oliver, A.M.1    Martin, F.2    Kearney, J.F.3
  • 15
    • 0032609574 scopus 로고    scopus 로고
    • CD21 high IgM high splenic B cells enriched in the marginal zone: distinct phenotypes and functions
    • discussion 51-52.
    • Martin, F. and Kearney, J. F., CD21 high IgM high splenic B cells enriched in the marginal zone: distinct phenotypes and functions. Curr. Top. Microbiol. Immunol. 1999. 246: 45-50; discussion 51-52.
    • (1999) Curr. Top. Microbiol. Immunol. , vol.246 , pp. 45-50
    • Martin, F.1    Kearney, J.F.2
  • 16
    • 33646580751 scopus 로고    scopus 로고
    • Peritoneal B-2 cells comprise a distinct B-2 cell population with B-1b-like characteristics
    • Hastings, W. D., Tumang, J. R., Behrens, T. W. and Rothstein, T. L., Peritoneal B-2 cells comprise a distinct B-2 cell population with B-1b-like characteristics. Eur. J. Immunol. 2006. 36: 1114-1123.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 1114-1123
    • Hastings, W.D.1    Tumang, J.R.2    Behrens, T.W.3    Rothstein, T.L.4
  • 17
    • 1642536499 scopus 로고    scopus 로고
    • Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells
    • Attanavanich, K. and Kearney, J. F., Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells. J. Immunol. 2004. 172: 803-811.
    • (2004) J. Immunol. , vol.172 , pp. 803-811
    • Attanavanich, K.1    Kearney, J.F.2
  • 18
    • 0026593440 scopus 로고
    • Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens
    • Eynon, E. E. and Parker, D. C., Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens. J. Exp. Med. 1992. 175: 131-138.
    • (1992) J. Exp. Med. , vol.175 , pp. 131-138
    • Eynon, E.E.1    Parker, D.C.2
  • 19
    • 0032543208 scopus 로고    scopus 로고
    • Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo
    • Townsend, S. E. and Goodnow, C. C., Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo. J. Exp. Med. 1998. 187: 1611-1621.
    • (1998) J. Exp. Med. , vol.187 , pp. 1611-1621
    • Townsend, S.E.1    Goodnow, C.C.2
  • 20
    • 0028882526 scopus 로고
    • Survival of mouse pancreatic islografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand
    • Parker, D. C., Greiner, D. L., Phillips, N. E., Appel, M. C., Steele, A. W., Durie, F. H., Noelle, R. J. et al., Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand. Proc. Natl. Acad. Sci. 1995. 92: 9560-9564.
    • (1995) Proc. Natl. Acad. Sci. , vol.92 , pp. 9560-9564
    • Parker, D.C.1    Greiner, D.L.2    Phillips, N.E.3    Appel, M.C.4    Steele, A.W.5    Durie, F.H.6    Noelle, R.J.7
  • 21
    • 0026451165 scopus 로고
    • B cells turn off virgin but not memory T cells
    • Fuchs, E. J. and Matzinger, P., B cells turn off virgin but not memory T cells. Science 1992. 258: 1156-1159.
    • (1992) Science , vol.258 , pp. 1156-1159
    • Fuchs, E.J.1    Matzinger, P.2
  • 22
    • 80051787580 scopus 로고    scopus 로고
    • B cells 'transduced' with TAT-fusion proteins can induce tolerance and protect mice from diabetes and EAE
    • Su, Y., Zhang, A. H., Li, X., Owusu-Boaitey, N., Skupsky, J. and Scott, D. W., B cells 'transduced' with TAT-fusion proteins can induce tolerance and protect mice from diabetes and EAE. Clin. Immunol. 2011. 140: 260-267.
    • (2011) Clin. Immunol. , vol.140 , pp. 260-267
    • Su, Y.1    Zhang, A.H.2    Li, X.3    Owusu-Boaitey, N.4    Skupsky, J.5    Scott, D.W.6
  • 23
    • 54049107281 scopus 로고    scopus 로고
    • Tolerance without clonal expansion: self-antigen-expressing B cells program self-reactive T cells for future deletion
    • Frommer, F., Heinen, T. J., Wunderlich, F. T., Yogev, N., Buch, T., Roers, A., Bettelli, E. et al., Tolerance without clonal expansion: self-antigen-expressing B cells program self-reactive T cells for future deletion. J. Immunol. 2008. 181: 5748-5759.
    • (2008) J. Immunol. , vol.181 , pp. 5748-5759
    • Frommer, F.1    Heinen, T.J.2    Wunderlich, F.T.3    Yogev, N.4    Buch, T.5    Roers, A.6    Bettelli, E.7
  • 24
    • 79961017479 scopus 로고    scopus 로고
    • Self-antigen presentation by mouse B cells results in regulatory T-cell induction rather than anergy or clonal deletion
    • Morlacchi, S., Soldani, C., Viola, A. and Sarukhan, A., Self-antigen presentation by mouse B cells results in regulatory T-cell induction rather than anergy or clonal deletion. Blood 2011. 118: 984-991.
    • (2011) Blood , vol.118 , pp. 984-991
    • Morlacchi, S.1    Soldani, C.2    Viola, A.3    Sarukhan, A.4
  • 25
    • 0037128649 scopus 로고    scopus 로고
    • Major histocompatibility complex class II presentation of cell- associated antigen is mediated by CD8alpha+ dendritic cells in vivo
    • Valdez, Y., Mah, W., Winslow, M. M., Xu, L., Ling, P. and Townsend, S. E., Major histocompatibility complex class II presentation of cell- associated antigen is mediated by CD8alpha+ dendritic cells in vivo. J. Exp. Med. 2002. 195: 683-694.
    • (2002) J. Exp. Med. , vol.195 , pp. 683-694
    • Valdez, Y.1    Mah, W.2    Winslow, M.M.3    Xu, L.4    Ling, P.5    Townsend, S.E.6
  • 26
    • 4043065702 scopus 로고    scopus 로고
    • Analyses of the in vivo trafficking of stoichiometric doses of an anti-complement receptor 1/2 monoclonal antibody infused intravenously in mice
    • Whipple, E. C., Shanahan, R. S., Ditto, A. H., Taylor, R. P. and Lindorfer, M. A., Analyses of the in vivo trafficking of stoichiometric doses of an anti-complement receptor 1/2 monoclonal antibody infused intravenously in mice. J. Immunol. 2004. 173: 2297-2306.
    • (2004) J. Immunol. , vol.173 , pp. 2297-2306
    • Whipple, E.C.1    Shanahan, R.S.2    Ditto, A.H.3    Taylor, R.P.4    Lindorfer, M.A.5
  • 27
    • 2442659071 scopus 로고    scopus 로고
    • A signal through OX40 (CD134) allows anergic, autoreactive T cells to acquire effector cell functions
    • Lathrop, S. K., Huddleston, C. A., Dullforce, P. A., Montfort, M. J., Weinberg, A. D. and Parker, D. C., A signal through OX40 (CD134) allows anergic, autoreactive T cells to acquire effector cell functions. J. Immunol. 2004. 172: 6735-6743.
    • (2004) J. Immunol. , vol.172 , pp. 6735-6743
    • Lathrop, S.K.1    Huddleston, C.A.2    Dullforce, P.A.3    Montfort, M.J.4    Weinberg, A.D.5    Parker, D.C.6
  • 28
    • 0033579933 scopus 로고    scopus 로고
    • Transfer of small resting B cells into immunodeficient hosts results in the selection of a self-renewing activated B cell population
    • Agenes, F. and Freitas, A. A., Transfer of small resting B cells into immunodeficient hosts results in the selection of a self-renewing activated B cell population. J. Exp. Med. 1999. 189: 319-330.
    • (1999) J. Exp. Med. , vol.189 , pp. 319-330
    • Agenes, F.1    Freitas, A.A.2
  • 30
    • 0030058657 scopus 로고    scopus 로고
    • The repertoire of T cells shaped by a single MHC/peptide ligand
    • Ignatowicz, L., Kappler, J. and Marrack, P., The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 1996. 84: 521-529.
    • (1996) Cell , vol.84 , pp. 521-529
    • Ignatowicz, L.1    Kappler, J.2    Marrack, P.3
  • 32
    • 0033919570 scopus 로고    scopus 로고
    • B-1 cells: the lineage question revisited
    • Herzenberg, L. A., B-1 cells: the lineage question revisited. Immunol. Rev. 2000. 175: 9-22.
    • (2000) Immunol. Rev. , vol.175 , pp. 9-22
    • Herzenberg, L.A.1
  • 33
    • 0026598333 scopus 로고
    • Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition
    • Kaye, J., Vasquez, N. J. and Hedrick, S. M., Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition. J. Immunol. 1992. 148: 3342-3353.
    • (1992) J. Immunol. , vol.148 , pp. 3342-3353
    • Kaye, J.1    Vasquez, N.J.2    Hedrick, S.M.3
  • 34
    • 58849161852 scopus 로고    scopus 로고
    • B lymphocytes promote expansion of regulatory T cells in oral tolerance: powerful induction by antigen coupled to cholera toxin B subunit
    • Sun, J. B., Flach, C. F., Czerkinsky, C. and Holmgren, J., B lymphocytes promote expansion of regulatory T cells in oral tolerance: powerful induction by antigen coupled to cholera toxin B subunit. J. Immunol. 2008. 181: 8278-8287.
    • (2008) J. Immunol. , vol.181 , pp. 8278-8287
    • Sun, J.B.1    Flach, C.F.2    Czerkinsky, C.3    Holmgren, J.4
  • 36
    • 48249147441 scopus 로고    scopus 로고
    • Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells
    • Wang, L., Pino-Lagos, K., de Vries, V. C., Guleria, I., Sayegh, M. H. and Noelle, R. J., Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells. Proc. Natl. Acad. Sci. USA 2008. 105: 9331-9336.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 9331-9336
    • Wang, L.1    Pino-Lagos, K.2    de Vries, V.C.3    Guleria, I.4    Sayegh, M.H.5    Noelle, R.J.6
  • 37
    • 77950070632 scopus 로고    scopus 로고
    • Effector and regulatory B cells: modulators of CD4(+) T cell immunity
    • Lund, F. E. and Randall, T. D., Effector and regulatory B cells: modulators of CD4(+) T cell immunity. Nat. Rev. Immunol. 2010. 10: 236-247.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 236-247
    • Lund, F.E.1    Randall, T.D.2
  • 38
    • 49249136452 scopus 로고    scopus 로고
    • Regulatory B cells as inhibitors of immune responses and inflammation
    • Bouaziz, J. D., Yanaba, K. and Tedder, T. F., Regulatory B cells as inhibitors of immune responses and inflammation. Immunol. Rev. 2008. 224: 201-214.
    • (2008) Immunol. Rev. , vol.224 , pp. 201-214
    • Bouaziz, J.D.1    Yanaba, K.2    Tedder, T.F.3
  • 39
    • 84860328975 scopus 로고    scopus 로고
    • Activation of CD4(+) Foxp3(+) regulatory T cells proceeds normally in the absence of B cells during EAE
    • Hoehlig, K., Shen, P., Lampropoulou, V., Roch, T., Malissen, B., O'Connor, R., Ries, S. et al., Activation of CD4(+) Foxp3(+) regulatory T cells proceeds normally in the absence of B cells during EAE. Eur. J. Immunol. 2012. 42: 1164-1173.
    • (2012) Eur. J. Immunol. , vol.42 , pp. 1164-1173
    • Hoehlig, K.1    Shen, P.2    Lampropoulou, V.3    Roch, T.4    Malissen, B.5    O'Connor, R.6    Ries, S.7
  • 40
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J. and Steinman, R. M., Dendritic cells and the control of immunity. Nature 1998. 392: 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 41
    • 0347717903 scopus 로고    scopus 로고
    • T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
    • Mempel, T. R., Henrickson, S. E. and Von Andrian, U. H., T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 2004. 427: 154-159.
    • (2004) Nature , vol.427 , pp. 154-159
    • Mempel, T.R.1    Henrickson, S.E.2    Von Andrian, U.H.3
  • 42
    • 0029978795 scopus 로고    scopus 로고
    • Dendritic cells but not B cells present antigenic complexes to class II-restricted T cells after administration of protein in adjuvant
    • Guery, J. C., Ria, F. and Adorini, L., Dendritic cells but not B cells present antigenic complexes to class II-restricted T cells after administration of protein in adjuvant. J. Exp. Med. 1996. 183: 751-757.
    • (1996) J. Exp. Med. , vol.183 , pp. 751-757
    • Guery, J.C.1    Ria, F.2    Adorini, L.3
  • 44
    • 84861205578 scopus 로고    scopus 로고
    • Toll-like receptor 4-activated B cells out-compete Toll-like receptor 9-activated B cells to establish peripheral immunological tolerance
    • Matheu, M. P., Su, Y., Greenberg, M. L., Blanc, C. A., Parker, I., Scott, D. W. and Cahalan, M. D., Toll-like receptor 4-activated B cells out-compete Toll-like receptor 9-activated B cells to establish peripheral immunological tolerance. Proc. Natl. Acad. Sci. USA 2012. 109: E1258-E1266.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109
    • Matheu, M.P.1    Su, Y.2    Greenberg, M.L.3    Blanc, C.A.4    Parker, I.5    Scott, D.W.6    Cahalan, M.D.7
  • 45
    • 0022494080 scopus 로고
    • Immunocompetent autoreactive B lymphocytes are activated cycling cells in normal mice
    • Portnoï, D., Freitas, A., Holmberg, D., Bandeira, A. and Coutinho, A., Immunocompetent autoreactive B lymphocytes are activated cycling cells in normal mice. J. Exp. Med. 1986. 164: 25-35.
    • (1986) J. Exp. Med. , vol.164 , pp. 25-35
    • Portnoï, D.1    Freitas, A.2    Holmberg, D.3    Bandeira, A.4    Coutinho, A.5
  • 46
    • 0023800017 scopus 로고
    • Preferential autoantibody reactivity of the preimmune B cell repertoire in normal mice
    • Souroujon, M., White-Scharf, M. E., Andreschwartz, J., Gefter, M. L. and Schwartz, R. S., Preferential autoantibody reactivity of the preimmune B cell repertoire in normal mice. J. Immunol. 1988. 140: 4173-4179.
    • (1988) J. Immunol. , vol.140 , pp. 4173-4179
    • Souroujon, M.1    White-Scharf, M.E.2    Andreschwartz, J.3    Gefter, M.L.4    Schwartz, R.S.5
  • 47
    • 33745224978 scopus 로고    scopus 로고
    • MHC transfer from APC to T cells following antigen recognition
    • Wetzel, S. A. and Parker, D. C., MHC transfer from APC to T cells following antigen recognition. Crit. Rev. Immunol. 2006. 26: 1-21.
    • (2006) Crit. Rev. Immunol. , vol.26 , pp. 1-21
    • Wetzel, S.A.1    Parker, D.C.2
  • 48
    • 55249118463 scopus 로고    scopus 로고
    • Intercellular trogocytosis plays an important role in modulation of immune responses
    • Ahmed, K. A., Munegowda, M. A., Xie, Y. and Xiang, J., Intercellular trogocytosis plays an important role in modulation of immune responses. Cell. Mol. Immunol. 2008. 5: 261-269.
    • (2008) Cell. Mol. Immunol. , vol.5 , pp. 261-269
    • Ahmed, K.A.1    Munegowda, M.A.2    Xie, Y.3    Xiang, J.4
  • 49
    • 34547135943 scopus 로고    scopus 로고
    • Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes
    • Skokos, D., Shakhar, G., Varma, R., Waite, J. C., Cameron, T. O., Lindquist, R. L., Schwickert, T. et al., Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes. Nat. Immunol. 2007. 8: 835-844.
    • (2007) Nat. Immunol. , vol.8 , pp. 835-844
    • Skokos, D.1    Shakhar, G.2    Varma, R.3    Waite, J.C.4    Cameron, T.O.5    Lindquist, R.L.6    Schwickert, T.7
  • 51
    • 34548810934 scopus 로고    scopus 로고
    • PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for V(H)11/V(H)12 and phosphatidylcholine binding
    • Zhong, X., Tumang, J. R., Gao, W., Bai, C. and Rothstein, T. L., PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for V(H)11/V(H)12 and phosphatidylcholine binding. Eur. J. Immunol. 2007. 37: 2405-2410.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 2405-2410
    • Zhong, X.1    Tumang, J.R.2    Gao, W.3    Bai, C.4    Rothstein, T.L.5
  • 53
    • 79957553099 scopus 로고    scopus 로고
    • Reprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis
    • Calderon-Gomez, E., Lampropoulou, V., Shen, P., Neves, P., Roch, T., Stervbo, U., Rutz, S. et al., Reprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis. Eur. J. Immunol. 2011. 41: 1696-1708.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 1696-1708
    • Calderon-Gomez, E.1    Lampropoulou, V.2    Shen, P.3    Neves, P.4    Roch, T.5    Stervbo, U.6    Rutz, S.7
  • 54
    • 2942625421 scopus 로고    scopus 로고
    • Complete protection from relapsing experimental autoimmune encephalomyelitis induced by syngeneic B cells expressing the autoantigen
    • Chen, C. C., Rivera, A., Dougherty, J. P. and Ron, Y., Complete protection from relapsing experimental autoimmune encephalomyelitis induced by syngeneic B cells expressing the autoantigen. Blood 2004. 103: 4616-4618.
    • (2004) Blood , vol.103 , pp. 4616-4618
    • Chen, C.C.1    Rivera, A.2    Dougherty, J.P.3    Ron, Y.4
  • 55
    • 35348957966 scopus 로고    scopus 로고
    • Tolerance induction by gene transfer to lymphocytes
    • Skupsky, J., Su, Y., Lei, T. C. and Scott, D. W., Tolerance induction by gene transfer to lymphocytes. Curr. Gene Ther. 2007. 7: 369-380.
    • (2007) Curr. Gene Ther. , vol.7 , pp. 369-380
    • Skupsky, J.1    Su, Y.2    Lei, T.C.3    Scott, D.W.4
  • 57
    • 54949141219 scopus 로고    scopus 로고
    • Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression
    • Matsushita, T., Yanaba, K., Bouaziz, J. D., Fujimoto, M. and Tedder, T. F., Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. J. Clin. Invest. 2008. 118: 3420-3430.
    • (2008) J. Clin. Invest. , vol.118 , pp. 3420-3430
    • Matsushita, T.1    Yanaba, K.2    Bouaziz, J.D.3    Fujimoto, M.4    Tedder, T.F.5
  • 58
    • 33646541712 scopus 로고    scopus 로고
    • OX40 (CD134) engagement drives differentiation of CD4+ T cells to effector cells
    • Huddleston, C. A., Weinberg, A. D. and Parker, D. C., OX40 (CD134) engagement drives differentiation of CD4+ T cells to effector cells. Eur. J. Immunol. 2006. 36: 1093-1103.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 1093-1103
    • Huddleston, C.A.1    Weinberg, A.D.2    Parker, D.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.