Disruption of cell-cell junctions and induction of pathological cytokines in the retinal pigment epithelium of light-exposed mice

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 7, 2013, Pages 4555-4562

  Narimatsu, Toshio ^a   Ozawa, Yoko ^a   Miyake, Seiji ^a   Kubota, Shunsuke ^a   Hirasawa, Manabu ^a   Nagai, Norihiro ^a   Shimmura, Shigeto ^a   Tsubota, Kazuo ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Age related macular degeneration; Light damage; Oxidative damage; Retina; Retinal pigment epithelium

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL) CYCLOHEXANECARBOXAMIDE; ACETYLCYSTEINE; BETA CATENIN; CYTOKINE; EOTAXIN; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; NERVE CELL ADHESION MOLECULE; REACTIVE OXYGEN METABOLITE; RHO KINASE; UNCLASSIFIED DRUG;

ABSORPTION SPECTROPHOTOMETRY; ACTIN FILAMENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL JUNCTION; CHOROID; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; LIGHT EXPOSURE; MACROPHAGE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RETINA MACULA AGE RELATED DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

AGE-RELATED MACULAR DEGENERATION; LIGHT DAMAGE; OXIDATIVE DAMAGE; RETINA; RETINAL PIGMENT EPITHELIUM;

ANALYSIS OF VARIANCE; ANIMALS; BIOLOGICAL MARKERS; CHOROID; CYTOKINES; CYTOSKELETON; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INTERCELLULAR JUNCTIONS; LIGHT; MACULAR DEGENERATION; MALE; MICE; MICE, INBRED BALB C; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RETINAL PIGMENT EPITHELIUM; RHO-ASSOCIATED KINASES;

EID: 84879971182     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-11572     Document Type: Article

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