메뉴 건너뛰기




Volumn 8, Issue 2, 2013, Pages 621-625

Lefty A protein inhibits TGF-β1-mediated apoptosis in human renal tubular epithelial cells

Author keywords

Apoptosis; Lefty protein; Smad2 protein; Smad3 protein; Transforming growth factor 1

Indexed keywords

LEFT RIGHT DETERMINATION FACTOR; LEFTY A PROTEIN; RECOMBINANT TUMOR NECROSIS FACTOR; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

EID: 84879970722     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1556     Document Type: Article
Times cited : (6)

References (25)
  • 1
    • 0037376701 scopus 로고    scopus 로고
    • Cell death induced by acute renal injury: A perspective on the contributions of apoptosis and necrosis
    • Padanilam BJ: Cell death induced by acute renal injury: a perspective on the contributions of apoptosis and necrosis. Am J Physiol Renal Physiol 284: F608-F627, 2003.
    • (2003) Am J Physiol Renal Physiol , vol.284
    • Padanilam, B.J.1
  • 2
    • 0027255942 scopus 로고
    • Apoptosis and disease
    • Carson DA and Ribeiro JM: Apoptosis and disease. Lancet 341: 1251-1254, 1993.
    • (1993) Lancet , vol.341 , pp. 1251-1254
    • Carson, D.A.1    Ribeiro, J.M.2
  • 4
    • 0035083846 scopus 로고    scopus 로고
    • Role of apoptosis of renal tubular cells in acute renal failure: Therapeutic implications
    • Rana A, Sathyanarayana P and Lieberthal W: Role of apoptosis of renal tubular cells in acute renal failure: therapeutic implications. Apoptosis 6: 83-102, 2001.
    • (2001) Apoptosis , vol.6 , pp. 83-102
    • Rana, A.1    Sathyanarayana, P.2    Lieberthal, W.3
  • 5
    • 79958794987 scopus 로고    scopus 로고
    • Apoptosis and acute kidney injury
    • Havasi A and Borkan SC: Apoptosis and acute kidney injury. Kidney Int 80: 29-40, 2011.
    • (2011) Kidney Int , vol.80 , pp. 29-40
    • Havasi, A.1    Borkan, S.C.2
  • 6
    • 0036226734 scopus 로고    scopus 로고
    • Role of apoptosis in fibrogenesis
    • Razzaque MS, Ahsan N and Taguchi T: Role of apoptosis in fibrogenesis. Nephron 90: 365-372, 2002.
    • (2002) Nephron , vol.90 , pp. 365-372
    • Razzaque, M.S.1    Ahsan, N.2    Taguchi, T.3
  • 8
    • 0036786834 scopus 로고    scopus 로고
    • TGF-beta signaling in renal disease
    • Böttinger EP and Bitzer M: TGF-beta signaling in renal disease. J Am Soc Nephrol 13: 2600-2610, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2600-2610
    • Böttinger, E.P.1    Bitzer, M.2
  • 9
    • 77955595272 scopus 로고    scopus 로고
    • TGF-beta signaling and the renal tubular epithelial cell: Too much, too little, and just right
    • Kopp JB: TGF-beta signaling and the renal tubular epithelial cell: too much, too little, and just right. J Am Soc Nephrol 21: 1241-1243, 2010.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1241-1243
    • Kopp, J.B.1
  • 10
    • 0031196157 scopus 로고    scopus 로고
    • Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: Their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos
    • Meno C, Ito Y, Saijoh Y, et al: Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos. Genes Cells 2: 513-524, 1997.
    • (1997) Genes Cells , vol.2 , pp. 513-524
    • Meno, C.1    Ito, Y.2    Saijoh, Y.3
  • 11
    • 0029932564 scopus 로고    scopus 로고
    • Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos
    • Meno C, Saijoh Y, Fujii H, et al: Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. Nature 381: 151-155, 1996.
    • (1996) Nature , vol.381 , pp. 151-155
    • Meno, C.1    Saijoh, Y.2    Fujii, H.3
  • 12
    • 0031011733 scopus 로고    scopus 로고
    • Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding
    • Kothapalli R, Buyuksal I, Wu SQ, Chegini N and Tabibzadeh S: Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding. J Clin Invest 99: 2342-2350, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 2342-2350
    • Kothapalli, R.1    Buyuksal, I.2    Wu, S.Q.3    Chegini, N.4    Tabibzadeh, S.5
  • 13
    • 0033361929 scopus 로고    scopus 로고
    • Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development
    • Kosaki K, Bassi MT, Kosaki R, et al: Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development. Am J Hum Genet 64: 712-721, 1999.
    • (1999) Am J Hum Genet , vol.64 , pp. 712-721
    • Kosaki, K.1    Bassi, M.T.2    Kosaki, R.3
  • 14
    • 0036250574 scopus 로고    scopus 로고
    • Establishment of vertebrate left-right asymmetry
    • Hamada H, Meno C, Watanabe D and Saijoh Y: Establishment of vertebrate left-right asymmetry. Nat Rev Genet 3: 103-113, 2002.
    • (2002) Nat Rev Genet , vol.3 , pp. 103-113
    • Hamada, H.1    Meno, C.2    Watanabe, D.3    Saijoh, Y.4
  • 15
    • 19944386909 scopus 로고    scopus 로고
    • Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies
    • Dvash T, Mayshar Y, Darr H, et al: Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies. Hum Reprod 19: 2875-2883, 2004.
    • (2004) Hum Reprod , vol.19 , pp. 2875-2883
    • Dvash, T.1    Mayshar, Y.2    Darr, H.3
  • 16
    • 78751505793 scopus 로고    scopus 로고
    • Rapid differential transport of Nodal and Lefty on sulfated proteoglycan-rich extracellular matrix regulates left-right asymmetry in Xenopus
    • Marjoram L and Wright C: Rapid differential transport of Nodal and Lefty on sulfated proteoglycan-rich extracellular matrix regulates left-right asymmetry in Xenopus. Development 138: 475-485, 2011.
    • (2011) Development , vol.138 , pp. 475-485
    • Marjoram, L.1    Wright, C.2
  • 17
    • 0035877586 scopus 로고    scopus 로고
    • Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor
    • Ulloa L and Tabibzadeh S: Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor. J Biol Chem 276: 21397-21404, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 21397-21404
    • Ulloa, L.1    Tabibzadeh, S.2
  • 18
    • 0037016712 scopus 로고    scopus 로고
    • Lefty contributes to the remodeling of extracellular matrix by inhibition of connective tissue growth factor and collagen mRNA expression and increased proteolytic activity in a fibrosarcoma model
    • Mason JM, Xu HP, Rao SK, et al: Lefty contributes to the remodeling of extracellular matrix by inhibition of connective tissue growth factor and collagen mRNA expression and increased proteolytic activity in a fibrosarcoma model. J Biol Chem 277: 407-415, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 407-415
    • Mason, J.M.1    Xu, H.P.2    Rao, S.K.3
  • 19
    • 0033667371 scopus 로고    scopus 로고
    • Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction
    • Miyajima A, Chen J, Lawrence C, et al: Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction. Kidney Int 58: 2301-2313, 2000.
    • (2000) Kidney Int , vol.58 , pp. 2301-2313
    • Miyajima, A.1    Chen, J.2    Lawrence, C.3
  • 20
    • 0037849935 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 potentiates renal tubular epithelial cell death by a mechanism independent of Smad signaling
    • Dai C, Yang J and Liu Y: Transforming growth factor-beta1 potentiates renal tubular epithelial cell death by a mechanism independent of Smad signaling. J Biol Chem 278: 12537-12545, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 12537-12545
    • Dai, C.1    Yang, J.2    Liu, Y.3
  • 21
    • 85027957316 scopus 로고    scopus 로고
    • Norcantharidin, a protective therapeutic agent in renal tubulointerstitial fibrosis
    • Li Y, Ge Y, Liu FY, et al: Norcantharidin, a protective therapeutic agent in renal tubulointerstitial fibrosis. Mol Cell Biochem 361: 79-83, 2012.
    • (2012) Mol Cell Biochem , vol.361 , pp. 79-83
    • Li, Y.1    Ge, Y.2    Liu, F.Y.3
  • 22
    • 80052030354 scopus 로고    scopus 로고
    • TGF-beta1 inhibits the growth and metastasis of tongue squamous carcinoma cells through Smad4
    • Wang X, Sun W, Zhang C, et al: TGF-beta1 inhibits the growth and metastasis of tongue squamous carcinoma cells through Smad4. Gene 485: 160-166, 2011.
    • (2011) Gene , vol.485 , pp. 160-166
    • Wang, X.1    Sun, W.2    Zhang, C.3
  • 23
    • 33749263537 scopus 로고    scopus 로고
    • Blockade of p38 mitogen-activated protein kinase and TGF-beta1/Smad signaling pathways rescues bone marrow-derived peritubular capillary endothelial cells in adriamycin-induced nephrosis
    • Li J, Deane JA, Campanale NV, Bertram JF and Ricardo SD: Blockade of p38 mitogen-activated protein kinase and TGF-beta1/Smad signaling pathways rescues bone marrow-derived peritubular capillary endothelial cells in adriamycin-induced nephrosis. J Am Soc Nephrol 17: 2799-2811, 2006.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2799-2811
    • Li, J.1    Deane, J.A.2    Campanale, N.V.3    Bertram, J.F.4    Ricardo, S.D.5
  • 24
    • 3242797424 scopus 로고    scopus 로고
    • Smad3 deficiency attenuates renal fibrosis, inflammation, and apoptosis after unilateral ureteral obstruction
    • Inazaki K, Kanamaru Y, Kojima Y, et al: Smad3 deficiency attenuates renal fibrosis, inflammation, and apoptosis after unilateral ureteral obstruction. Kidney Int 66: 597-604, 2004.
    • (2004) Kidney Int , vol.66 , pp. 597-604
    • Inazaki, K.1    Kanamaru, Y.2    Kojima, Y.3
  • 25
    • 84894892577 scopus 로고    scopus 로고
    • Transfection and expression of Smad7 inhibits transforming growth factor-β1 effects on renal tubular cells (Chinese)
    • Huang YJ, Mei YM, Wang YQ, et al: Transfection and expression of Smad7 inhibits transforming growth factor-β1 effects on renal tubular cells (Chinese). J Third Military Medical University 25: 1049-1052, 2003.
    • (2003) J Third Military Medical University , vol.25 , pp. 1049-1052
    • Huang, Y.J.1    Mei, Y.M.2    Wang, Y.Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.