Multimodal assessment of in vivo metabolism with hyperpolarized [1- 13C]MR spectroscopy and 18F-FDG PET imaging in hepatocellular carcinoma tumor-bearing rats

Journal of Nuclear Medicine

Volumn 54, Issue 7, 2013, Pages 1113-1119

  Menzel, Marion I ^a   Farrell, Eliane V ^b   Janich, Martin A ^a   Khegai, Oleksandr ^a,b   Wiesinger, Florian ^a   Nekolla, Stephan ^b   Otto, Angela M ^b   Haase, Axel ^b   Schulte, Rolf F ^a   Schwaiger, Markus ^b  

^a GE GLOBAL RESEARCH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

13C; Animal imaging; Molecular imaging; MR imaging; PET

Indexed keywords

ALANINE; FLUORODEOXYGLUCOSE F 18; LACTATE DEHYDROGENASE; LACTIC ACID; LACTIC ACID C 13; PYRUVIC ACID; PYRUVIC ACID C 13; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER TISSUE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG UPTAKE; GASTROINTESTINAL TRACT; GLYCOLYSIS; HISTOPATHOLOGY; HYPERPOLARIZATION; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; ONCOLOGICAL PARAMETERS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RAT; SIGNAL NOISE RATIO; TUMOR METABOLISM;

13C; ANIMAL IMAGING; MOLECULAR IMAGING; MR IMAGING; PET;

ANIMALS; CARBON ISOTOPES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; FLUORODEOXYGLUCOSE F18; LIVER NEOPLASMS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; POSITRON-EMISSION TOMOGRAPHY; PROTONS; RADIOPHARMACEUTICALS; RATS;

EID: 84879954471     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.112.110825     Document Type: Article

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