Critical role of histone acetylation by p300 in human placental 11β-HSD2 expression

Journal of Clinical Endocrinology and Metabolism

Volumn 98, Issue 7, 2013, Pages

  Li, Jianneng ^a   Wang, Wangsheng ^a   Liu, Chao ^a   Wang, Weihua ^a   Li, Wenjiao ^b   Shu, Qun ^b   Chen, Zi Jiang ^c   Sun, Kang ^a,c  

^a FUDAN UNIVERSITY   (China)

^b Department of Gynecology   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 2; CYCLIC AMP; E1A ASSOCIATED P300 PROTEIN; HISTONE H3; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1;

ARTICLE; CELL NUCLEUS; CHORION VILLUS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FEMALE; HISTONE ACETYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PLACENTA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SYNCYTIOTROPHOBLAST; TROPHOBLAST;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; ACETYLATION; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLIC AMP; ENZYME INDUCTION; ENZYME INHIBITORS; FEMALE; HISTONES; HUMANS; P300-CBP TRANSCRIPTION FACTORS; PLACENTA; PLACENTATION; PREGNANCY; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RECOMBINANT PROTEINS; RNA INTERFERENCE; SP1 TRANSCRIPTION FACTOR; TROPHOBLASTS;

EID: 84879919283     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-4291     Document Type: Article

References (39)

1. Cole TJ, Blendy JA, Monaghan AP, et al. Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev. 1995; 9:1608-1621.
2. Ward RM. Pharmacologic enhancement of fetal lung maturation. Clin Perinatol. 1994;21:523-542. (Pubitemid 24284508)
3. Seckl JR. Glucocorticoid programming of the fetus; adult phenotypes and molecular mechanisms. Mol Cell Endocrinol. 2001;185: 61-71. (Pubitemid 33103954)
4. Seckl JR. Prenatal glucocorticoids and long-term programming. Eur J Endocrinol. 2004;151(Suppl 3):U49-U62. (Pubitemid 39627056)
5. Campbell AL, Murphy BE. The maternal-fetal cortisol gradient during pregnancy and at delivery. J Clin Endocrinol Metab. 1977;45: 435-440. (Pubitemid 8194479)
6. Krozowski Z, MaGuire JA, Stein-Oakley AN, Dowling J, Smith RE, Andrews RK. Immunohistochemical localization of the 11β-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta. J Clin Endocrinol Metab. 1995;80:2203-2209.
7. Sun K, Yang K, Challis JR. Differential regulation of 11β-hydroxysteroid dehydrogenase type 1 and 2 by nitric oxide in cultured human placental trophoblast and chorionic cell preparation. Endocrinology. 1997;138:4912-4920. (Pubitemid 27460931)
8. Benediktsson R, Calder AA, Edwards CR, Seckl JR. Placental 11β-hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure. Clin Endocrinol (Oxf). 1997;46:161-166. (Pubitemid 27122161)
9. Gitau R, Cameron A, Fisk NM, Glover V. Fetal exposure to maternal cortisol. Lancet. 1998;352:707-708. (Pubitemid 28398713)
10. Li JN, Ge YC, Yang Z, et al. The Sp1 transcription factor is crucial for the expression of 11β-hydroxysteroid dehydrogenase type 2 in human placental trophoblasts. J Clin Endocrinol Metab. 2011;96: E899-E907.
11. Kornberg RD. Chromatin structure: a repeating unit of histones and DNA. Science. 1974;184:868-871.
12. Shahbazian MD, Grunstein M. Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem. 2007;76:75-100.
13. Kouzarides T. Chromatin modifications and their function. Cell. 2007;128:693-705. (Pubitemid 46273577)
14. Hassig CA, Schreiber SL. Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs. Curr Opin Chem Biol. 1997;1:300-308. (Pubitemid 127437155)
15. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature. 1993;365:855-859. (Pubitemid 23341031)
16. Harlow E, Whyte P, Franza BR Jr, Schley C. Association of adenovirus early-region 1A proteins with cellular polypeptides. Mol Cell Biol. 1986;6:1579-1589. (Pubitemid 16089494)
17. Eckner R, Ewen ME, Newsome D, et al. Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 1994;8:869-884.
18. Boyes J, Byfield P, Nakatani Y, Ogryzko V. Regulation of activity of the transcription factor GATA-1 by acetylation. Nature. 1998; 396:594-598. (Pubitemid 28563723)
19. Goldman PS, Tran VK, Goodman RH. The multifunctional role of the co-activator CBP in transcriptional regulation. Recent Prog Horm Res. 1997;52:103-119; discussion 119-120.
20. Gu W, Roeder RG. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell. 1997;90: 595-606. (Pubitemid 27357952)
21. Hung JJ, Wang YT, Chang WC. Sp1 deacetylation induced by phorbol ester recruits p300 to activate 12(S)-lipoxygenase gene transcription. Mol Cell Biol. 2006;26:1770-1785.
22. Kliman HJ, Nestler JE, Sermasi E, Sanger JM, Strauss JF 3rd. Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae. Endocrinology. 1986;118: 1567-1582. (Pubitemid 16078536)
23. Ni XT, Duan T, Yang Z, Guo CM, Li JN, Sun K. Role of human chorionic gonadotropin in maintaining 11β-hydroxysteroid dehydrogenase type 2 expression in human placental syncytiotrophoblasts. Placenta. 2009;30:1023-1028.
24. Bowers EM, Yan G, Mukherjee C, et al. Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chem Biol. 2010;17:471-482.
25. Schacter DL, Chiu CY, Ochsner KN. Implicit memory: a selective review. Annu Rev Neurosci. 1993;16:159-182. (Pubitemid 23074004)
26. Sun K, Yang K, Challis JR. Differential expression of 11--hydroxysteroid dehydrogenase types 1 and 2 in human placenta and fetal membranes. J Clin Endocrinol Metab. 1997;82:300-305. (Pubitemid 27021315)
27. +dependent 11β-hydroxysteroid dehydrogenase (HSD11K) gene in JEG-3 human choriocarcinoma cells. Mol Cell Endocrinol. 1996;121:93-99.
28. Wang L, Tang Y, Cole PA, Marmorstein R. Structure and chemistry of the p300/CBP and Rtt109 histone acetyltransferases: implications for histone acetyltransferase evolution and function. Curr Opin Struct Biol. 2008;18:741-747.
29. Yao TP, Oh SP, Fuchs M, et al. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell. 1998;93:361-372. (Pubitemid 28232081)
30. Szerlong HJ, Prenni JE, Nyborg JK, Hansen JC. Activator-dependent p300 acetylation of chromatin in vitro: enhancement of transcription by disruption of repressive nucleosome-nucleosome interactions. J Biol Chem. 2010;285:31954-31964.
31. Kao LC BG, Kopf GS, Coutifaris C, Strauss JF III. Differentiation of humantrophoblasts: structure-function relationships. In: Leung PC, Hsueh AJ, Friesen HG, eds. Molecular Basis of Reproductive Endocrinology. New York, NY: Springler-Verlag; 1993:159-170.
32. Keryer G, Alsat E, Tasken K, Evain-Brion D. Cyclic AMP-dependent protein kinases and human trophoblast cell differentiation in vitro. J Cell Sci. 1998;111 (Pt 7):995-1004. (Pubitemid 28196082)
33. Kimura AP, Sizova D, Handwerger S, Cooke NE, Liebhaber SA. Epigenetic activation of the human growth hormone gene cluster during placental cytotrophoblast differentiation. Mol Cell Biol. 2007;27:6555-6568. (Pubitemid 47435759)
34. Knöfler M, Saleh L, Strohmer H, Husslein P, Wolschek MF. Cyclic AMP- and differentiation-dependent regulation of the proximal alphaHCG gene promoter in term villous trophoblasts. Mol Hum Reprod. 1999;5:573-580. (Pubitemid 29251638)
35. Cheng YH, Nicholson RC, King B, Chan EC, Fitter JT, Smith R. Corticotropin-releasing hormone gene expression in primary placental cells is modulated by cyclic adenosine 3′,5′-monophosphate. J Clin Endocrinol Metab. 2000;85:1239-1244. (Pubitemid 32269379)
36. Grammatopoulos D, Milton NG, Hillhouse EW. The human myometrial CRH receptor: G proteins and second messengers. Mol Cell Endocrinol. 1994;99:245-250. (Pubitemid 24076972)
37. Zygmunt M, Hahn D, Münstedt K, Bischof P, Lang U. Invasion of cytotrophoblastic JEG-3 cells is stimulated by hCG in vitro. Placenta. 1998;19:587-593. (Pubitemid 28528846)
38. Riley SC, Walton JC, Herlick JM, Challis JR. The localization and distribution of corticotropin-releasing hormone in the human placenta and fetal membranes throughout gestation. J Clin Endocrinol Metab. 1991;72:1001-1007. (Pubitemid 21921798)
39. Fahlbusch FB, Ruebner M, Volkert G, et al. Corticotropin-releasing hormone stimulates expression of leptin, 11β-HSD2 and syncytin-1 in primary human trophoblasts. Reprod Biol Endocrinol. 2012;10:80.