Cyclic AMP-dependent protein kinases and human trophoblast cell differentiation in vitro

Journal of Cell Science

Volumn 111, Issue 7, 1998, Pages 995-1004

  Keryer, Guy ^a   Alsat, Eliane ^a   Taskén, Kjetil ^b   Evain Brion, Danièle ^a  

^a INSERM   (France)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

cAMP dependent protein kinase; Cell fusion; Human placenta; Syncytiotrophoblast; Trophoblast cell

Indexed keywords

8 BROMO CYCLIC AMP; CADHERIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DESMOPLAKIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE;

ARTICLE; CELL DIFFERENTIATION; CELL FUSION; CELLULAR DISTRIBUTION; CENTROSOME; CYTOTROPHOBLAST; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SYNCYTIOTROPHOBLAST; TROPHOBLAST;

CELL DIFFERENTIATION; CELL FUSION; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; FEMALE; GIANT CELLS; HUMANS; LABOR, OBSTETRIC; PLACENTA; PREGNANCY; RNA, MESSENGER; SUBCELLULAR FRACTIONS; TRANSCRIPTION, GENETIC; TROPHOBLASTS;

EID: 0031956918     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Albrecht, E. D. and Pepe, G. J. (1990). Placental steroid hormone biosynthesis in primate pregnancy. Endocr. Rev. 11, 124-150.
2. Algrain, M., Turunen, O., Vaheri, A., Louvard, D. and Arpin, M. (1993). Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker. J. Cell. Biol. 120, 129-139.
3. Alsat, E., Mirlesse, V., Fondacci, C., Dodeur, M. and Evain-Brion, D. (1991). Parathyroid hormone increases epidermal growth factors receptors in cultured human trophoblastic cells from early and term placenta. J. Clin. Endocrinol. Metab. 73, 288-295.
4. Alsat, E., Mensier, A., Mirlesse, V., Dodeur, M., Fondacci, C. and Evain-Brion, D. (1992). Effect of PTH on cAMP production and EGF receptor binding in cultured trophoblast cells from first trimester placenta. Trophoblast Res. 6, 225-235.
5. Alsat, E., Haziza, J. and Evain-Brion, D. (1993). Increase in epidermal growth factor receptor and its messenger ribonucleic acid levels with differentiation of human trophoblast cells in culture. J. Cell. Physiol. 154, 122-128.
6. Alsat, E., Wyplosz, P., Malassiné, A. Guibourdenche, J., Porquet, D., Nessmann, C. and Evain-Brion, D. (1996). Hypoxia impairs cell fusion and differentiation process in human cytotrophoblast, in vitro. J. Cell. Physiol. 168, 346-353.
7. Beebe, S. J., Oyen, O., Sandberg, M., Froysa, A., Hansson, V. and Jahnsen, T. (1990). Molecular cloning of a tissue-specific protein kinase (Cγ) from human testis - representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase. Mol. Endocrinol. 4, 465-475.
8. Benirschke, K. and Kaufmann, P. (1990). Basic structures of the villous trees. In Pathology of the Human Placenta. (ed. K. Benirschke and P. Kaufmann), pp. 22-70. Springer-Verlag, New York.
9. Berryman, M., Franck, Z. and Bretscher, A. (1993). Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cells. J. Cell Sci. 105, 1025-1043.
10. Bretscher, A. (1983). Purification of an 80,000-dalton protein is a component of the isolated microvillous cytoskeleton and its localization in non-muscle cells. J. Cell Blol. 97, 425-432.
11. Bretscher, A. (1989). Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor. J. Cell Blol. 108, 921-930.
12. Cemerikic-Jakic, B. and Pavlovic-Hournac, M. (1984). Modification of protein kinase pattern in human placenta during gestation. Placenta 5, 443-452.
13. Chijiwa, T., Mishima, A., Hagiwara, M., Sano, M., Hayashi, K., Inoue, T., Naito, K. Toshioka, T. and Hidaka, H. (1990). Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthetized selective inhibitor of cyclic-AMP-dependent protein kinase, N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H89), of PC12D Phaeochromocytoma cells. J. Biol. Chem. 266, 5267-527.
14. Coutifaris, C., Kao, K.-C., Sehdev, H. M., Chin, U., Babalola, G. O., Blaschuck, O. W. and Strauss III J. F. (199I). E-cadherin expression during the differentiation of human trophohlasts. Development 113, 767-777.
15. Cronier, L., Bastide, B., Hervé, J. C., Deléze. J. and Malassiné, A. 11994). Gap junctional communication during irophohlust differentiation: influence of human chorionic gonadotropin Endocrinology 135, 402-408.
16. Cronier, L., Alsat, E., Hervé, J. C., Deléze, J. and Malassiné. A. (1997). Dexamethasone stimulates Gap junctional communication, peptide hormone production and differentiation in human term trophobhist. Trophohlast Res. 10, 363-375.
17. Dell'Acqua, M. L. and Scott, J, D. 11997). Protein kinase A anchoring. J. Biol. Client. 212. 12881-12884.
18. Douglas, G. C. and King, B. Y. (1990). Differentiation of human trophoblast cells in vitro as revealed by immunocytochemical staining of desmoplakin and nuclei. J. Cell Sci. 96, 131-141.
19. Dransfield, D. T., Bradford, A. J., Smith, J., Martin, M., Roy, C., Mangeat, P. and Goldenrfng, J. R. (1997). Ezrin is a cyclic AMP-dependem protein kinase anchoring protein. EMBO J. 16. 35-43.
20. Eaton, B. M. and Contractor, S. F. (1993). In vitro assessement of trophoblast receptors and placental transport mechanisms. In The Human Placenta (ed. C. W. G. Redman, I. L. Sargent and P. M. Starkey), pp. 471-503. Blackwell Scientific Publications. London.
21. Feinman, M. A., Kliman, H. J., Caltabiano, S. and Strauss III, J. F. (1986). 8-Bromo-3′,5′-adenosine monophosphate stimulates the endocrine activity of human cytotrophoblasts in culture, J. Clin. Endocrinol. Metab. 63. 1211-1217.
22. Gjertsen, B. T., Mellgren, G., Otten, A., Maronde, E., Genieser, H.-G., Jastorff, B., Vintermyr, O. K., McKnight, G. S. and Doeskeland, S. O. (1995). Novel (Rp) cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. J. Biol. Chem. 270, 20599-20607.
23. Jasmin, B. J., Cartaud, J., Bornens, M. and Changeux, J. P. (1989). Golgi apparatus in chick skeletal muscle: changes in its distribution during end plate development and after denervation. Proc. Nat. Acad. SCi. USA 86, 7218-7222.
24. Kao, L.-C., Babalola, G. O., Kopf, G. S., Coutifaris, C. and Strauss III, J. F. (1992). Differentiation of human trophoblasts: structure-function relationships. In Molecular Basis of Reproductive Endocrinology (ed. P. C. K. Leung). Springer-Verlag, New York.
25. Kcryer, G., Alsat, E., Tasken, K. and Evain-Brion, D. (1997). Cyclic AMP- dependent protein kinase expression and subcellular distribution during cytotrophoblast differentiation. Placenta 18, A33.
26. Kliman, H. J., Nestler, J. E., Sermasi, E., Sanger, J. M. and Strauss III, J. F. (1986). Purification, characterization and in vitro differentiation of cytotrophoblasts from human term placentae. Endocrinology 118, 1567-1582.
27. 4. Nature 221, 680-685.
28. Levy, F. O., Oyen, O., Sandberg, M., Taskén, K., Eskild, W., Hansson, V. and Jahnsen, T. (1988). Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3′,5′-cyclic adenosine monophosphate-dependent protein kinase from human testis. Mol. Endocrinol. 2, 1364-1373.
29. Lohmann, S. M. and Walter, U. (I984). Regulation of the cellular and subcellular and distribution of nuclcotide-dependent protein kinases. Adv. Cyclic Nuc. Prot. PHosph. Res. 18, 63-102.
30. Lorimer, I. A., Mason, M. E. and Sanvwal, B. D. (1987). Levels of type I cAMP-dependent protein kinase regulatory subunit are regulated by changes in turnover rate during skeletal myogenesis. J. Biol. Chem. 262, 17200- 17205.
31. McKnight, S. (1991). Cyclic AMP second messenger systems. Curr. Opin. Cell. Biol. 3, 213-217.
32. Midgley, A. R., Pierce, G.B., Deneau, G. A. and Gosling, J. R. G. (1963). Morphogenesis of syncytiotrophoblast in vivo: an autoradiographic demonstration. Science 141, 349-350.
33. Moore, J. J., Baker, J. V. and Whitsett, J. A. (1983). cAMP-dependent protein kinase and cAMP. cGMP and calcium stimulated phosphorylation in human placenta: comparison of cytosol and membrane fractions. Trophoblast. Res, 1. 185-196.
34. Mrrish, D. W., Bhardwaj, D., Dabbagh, L. K., Marusyk, H. and Siy, O. (1987). Epidermal growth factor induces differentiation and secretion of human chorionic gonadotropin and placental lactogen in normal human placenta. J. Clin. Endocrinol, Metab. 65, 1282-1290.
35. Morrish, D. W., Bhardwaj, D. and Paras, M. T. T. (1991). Transforming growth factor βl inhibits placental differentiation and human chorionic gonadotropin and human placental lactogen secretion. Endocrinologv 129, 22-26.
36. Nigg, K. A., Schäfer G., Hlltz, H. and Eppcnbcrger, H. M. (1985). CyclicAMP-dependent protein kinase type II is associated with the Golgi complex and cemrosomes. Cell 41, 1039-1051.
37. Ogren, L. and Talamantes, F. (1994). The placenta as an endocrine organ: polypeiides. In The Physiology of Reproduction (ed. E. Knobil and J. D. Neil), pp. 875-945. Raven Press, New York.
38. Oyen, O., Mykitbust. F., Scott, J. D., Haussen, V. and Juliusen, T. (1989). Human testis cDNA for the regulatory subunit Rlla of eAMP-dependent protein kinase encodes an alternate amino-terminal region. FEBS Lett. 246, 57-64.
39. Petraglia, F., Florin, P., Nappi, C. and Genazzani, A. R. (1996). Peptide signaling in human placenta and membranes: autocrine. paracrine and endocrine mechanisms. Endocrine Rev, 17, 156-186.
40. Rebut-Bonneton, C., Segond, N., Demignun, J., Porquet, D. and EvainBrion, D. (1992). Effects of calcitonin on human trophoblastic cells in culture: Absence of autocrine effect. Mol. Cell. Endocnnol. 85, 65-71.
41. Roulier, S., Rochette-Egly, C., Rebut-Bonneton, C., Porquet, D. and EvalnBrion, D. (1994). Nuclear retinoic acid receptor characterization in cultured human trophoblast cells: effect of retinoic acid on epidermal growth factor receptor expression. Mol. Cell. Endocnnol. 105, 165-173.
42. Rubin, C. S. (1994) A kinase anchor proteins and the intraccllular targeting of signals carried by cyclic AMP. Biochim. Biophys. Acta 1224, 467-479.
43. Sandberg, M., Taskén, K., Oyen, O., Hansson V. and Jahnsen, T. (1987). Molecular cloning. cDNA structure and deduced amino acid sequence for a type I regulatory subunit of cAMP-dependent protein kinase from human testis. Biochem. Biophys. Res. Commun. 149, 939-945.
44. Shi, Q. J., Lei, Z. M., Rao, Ch. V. and Lin, L. (1993). Novel role of Human Chorionic Gonadotropin in Differentiation of Human Cytotrophoblasts. Endocrinology 132, 1387-1395.
45. Skålhegg, B. S., Landmark, B. F., Foss, K. B., Lohmann, S. M., Hansson, V., Lea, T. and Jahnsen, T. (1992). Identification, purification, and characterization of subunits of cAMP-dependent protein kinase in human testis. Reverse mobilities of human RII alpha and RII beta on sodium dodecyl sulfate-polyacrylamide gel electrophoresis compared with rat and bovine RIIs. J. Biol. Chem. 267, 5374-5379.
46. Solberg, R., Taskén, K., Keiserud, A. and Jahnsen, T. (1991). Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RIβ of cAMP-dependent protein kinases. Biochem. Biophys. Res. Commun. 176, 166-172.
47. Strauss III, J. F., Kido, S., Sayegh, R., Sakuragi, N. and Gafvels, M. E. (1992). The cAMP signalling system and human trophoblast function. Placenta 13, 389-403.
48. Stephanou, A., Sarlis, N. J., Richards, R. and Hand werger, S. (1994). Expression of retinoic acid receptor subtypes and cellular retinoic acid binding protein-II mRNAs during differentiation of human trophoblast cells. Biochem. Biophys. Res. Commun. 202, 772-780.
49. Taskén, K., Skålhegg, B. S., Solberg, R., Andersson, K., Taylor, S. S., Lea, T., Blomhoff, H. K., Jahnsen, T. and Hansson, V. (1993) Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of Ria-Riβ heterodimeric complexes. J., Biol. Chem. 268, 21276-21283.
50. Taskén, K., Solberg, R., Foss, K.B., Skålhegg, B. S., Hansson V. and Jahnsen, T. (1995). cAMP-dependent protein kinase (vertebrates). In The Protein Kinase: Protein-Serine Kinases (ed. G. Hardie and S. Hanks), pp. 58-63. Academic Press, London.
51. Taylor, R. N., Newman, E. D. and Chen, S. (1991). Forskolin and methotrexate induce an intermediate trophoblast phenotype in cultured choriocarcinoma cells. Am. J. Obstet. Gynecol. 164, 204-209.
52. Taylor, S. S., Buechler, J. A. and Yonemoto, W. (1990). cAMP-dependent protein kinase: Framework for a diverse family of regulatory enzymes. Ann. Rev. Biochem. 59, 971-1005.
53. Teigmann, R., Maronde, E., Taskén, K. and Gellersen, B. (1997). Activated protein kinase A is required for differentiation-dependent transcription of the decidual prolactin gene in human endometrial stromal cells. Endocrinology 138, 929-937.
54. Towbin, H., Staehelin, T. and Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some application. Pmc. Nat. Acad. Sci. USA 76, 4350-4354.
55. Wakelam, M. J. O. (1985). The fusion of myoblasts. Biochem. J. 228, 1-12.
56. Wice, B., Menton, D., Geuze, H. and Schwartz, A. L. (1990). Modulators of cyclic AMP metabolism induce syncytiotrophoblast formation in vitro. Exp. Cell. Res. 186, 306-316.
57. Zambonin-Zallone, A., Teti, A. and Primavera, M. V. (1984). Monocytes from circulating blood fuse in vitro with purified osteoclasts in primary culture. J. Cell Sci. 77, 335-342.