Superior renoprotective effects of the combination of breviscapine with enalapril and its mechanism in diabetic rats

Phytomedicine

Volumn 20, Issue 10, 2013, Pages 820-827

  Xu, Xing Xin ^a   Zhang, Wei ^a   Zhang, Pei ^a   Qi, Xiang Ming ^a   Wu, Yong Gui ^a   Shen, Ji Jia ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Breviscapine; Diabetic nephropathy; Enalapril; Protein kinase C; Transforming growth factor 1

Indexed keywords

BREVISCAPINE; ENALAPRIL; PROTEIN KINASE C; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENAL PROTECTION; TISSUE LEVEL; URINE LEVEL;

3-NITROTYROSINE; 3-NT; A(G); A(M); ACE; AER; ALBUMIN EXCRETION RATE; ANGIOTENSIN-CONVERTING ENZYME; BODY WEIGHT; BREVISCAPINE; BW; DIABETIC NEPHROPATHY; DN; ENALAPRIL; GLOMERULAR CROSS-SECTIONAL AREA; GLOMERULAR VOLUME; ICAM-1; INTERCELLULAR ADHESION MOLECULE-1; KIDNEY WEIGHT; KW; MALONDIALDEHYDE; MCP-1; MDA; MESANGIAL AREA; MONOCYTE CHEMOATTRACTANT PROTEIN-1; PKC; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; ROS; SABC; STREPTAVIDIN-BIOTIN-PEROXIDASE COMPLEX; STREPTOZOTOCIN; STZ; TGFΒ1; TII; TRANSFORMING GROWTH FACTOR Β1; TUBULOINTERSTITAL INJURY; V(G);

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DRUG THERAPY, COMBINATION; ENALAPRIL; FLAVONOIDS; KIDNEY; MALE; PHYTOTHERAPY; RANDOM ALLOCATION; RATS; RATS, WISTAR; TRANSFORMING GROWTH FACTOR BETA1;

ERIGERON BREVISCAPUS; RATTUS;

EID: 84879889075     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.03.027     Document Type: Article

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