Role of protein kinase C-angiotensin II pathway for extracellular matrix production in cultured human mesangial cells exposed to high glucose levels

Diabetes Research and Clinical Practice

Volumn 59, Issue 1, 2003, Pages 25-30

  Ikehara, Kayoko ^a,b   Tada, Hisaya ^a,c   Kuboki, Koji ^a   Inokuchi, Toshiki ^a  

^a TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Saiseikai Kanagawa ken Hospital   (Japan)

^c Tada Clinic   (Japan)

Author keywords

Angiotensin II; Fibronectin; Mesangial cells; Protein kinase C; Type IV collagen

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; BISINDOLYLMALEIMIDE; CANDESARTAN HEXETIL; COLLAGEN TYPE 4; FIBRONECTIN; GLUCOSE; PHORBOL DIBUTYRATE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR BETA1; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; BENZIMIDAZOLE DERIVATIVE; BIPHENYL DERIVATIVE; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; TETRAZOLE DERIVATIVE; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA; VASOCONSTRICTOR AGENT;

ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; INCUBATION TIME; MESANGIUM; MESANGIUM CELL; PROTEIN LOCALIZATION; PROTEIN SECRETION; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; METABOLISM;

ANGIOTENSIN II; BENZIMIDAZOLES; BIPHENYL COMPOUNDS; CELLS, CULTURED; COLLAGEN TYPE IV; CULTURE MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; GLOMERULAR MESANGIUM; GLUCOSE; HUMANS; INDOLES; MALEIMIDES; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; RECEPTORS, ANGIOTENSIN; TETRAZOLES; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; VASOCONSTRICTOR AGENTS;

EID: 0037212285     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8227(02)00194-8     Document Type: Article

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