Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc

Nephrology Dialysis Transplantation

Volumn 28, Issue 6, 2013, Pages 1417-1425

  Arany, Istvan ^a   Clark, Jeb ^a   Reed, Dustin K ^a   Juncos, Luis A ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Cytochrome c; Mitochondria; Nicotine; p66shc; ROS

Indexed keywords

CYTOCHROME C; MEMBRANE PROTEIN; NICOTINE; PROTEIN P66SHC; REACTIVE OXYGEN METABOLITE; SERINE; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR PARAMETERS; CONTROLLED STUDY; DISEASE EXACERBATION; DNA METHYLATION; EPIGENETICS; GENE MUTATION; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; KIDNEY ISCHEMIA; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; LONG TERM EXPOSURE; MALE; MITOCHONDRIAL DEPOLARIZATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPERFUSION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

CYTOCHROME C; MITOCHONDRIA; NICOTINE; P66SHC; ROS;

ACUTE KIDNEY INJURY; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CYTOCHROMES C; HYDROGEN PEROXIDE; IMMUNOPRECIPITATION; KIDNEY TUBULES, PROXIMAL; LUCIFERASES; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NICOTINE; NICOTINIC AGONISTS; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SERINE; SHC SIGNALING ADAPTOR PROTEINS; TRANSCRIPTIONAL ACTIVATION;

EID: 84879853734     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs596     Document Type: Article

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