Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration

Journal of Cell Science

Volumn 126, Issue 12, 2013, Pages 2617-2628

  Li, Xiang ^a   Zhou, Qi ^a   Sunkara, Manjula ^b   Kutys, Matthew L ^c   Wu, Zhaofei ^a   Rychahou, Piotr ^a   Morris, Andrew J ^b   Zhu, Haining ^b   Evers, B Mark ^a   Huang, Cai ^a,d  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

HECTD1; Invasion; Metastasis; PIP5K1C; Ubiquitylation

Indexed keywords

BORTEZOMIB; CARFILZOMIB; HECTD1 ENZYME; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE 5 KINASE TYPE I GAMMA; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PROTEIN SMURF1; PROTEIN SMURF2; REGULATOR PROTEIN; TALIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CELL; CANCER CELL; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME SUBSTRATE; FEMALE; FOCAL ADHESION; HUMAN; HUMAN CELL; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UBIQUITINATION; UMBILICAL VEIN ENDOTHELIAL CELL;

HECTD1; INVASION; METASTASIS; PIP5K1C; UBIQUITYLATION;

ANIMALS; CELL LINE; CELL MOVEMENT; CHO CELLS; CRICETINAE; CRICETULUS; FOCAL ADHESIONS; HEK293 CELLS; HUMANS; INTEGRIN BETA CHAINS; LYSINE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); TALIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84879850215     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.117044     Document Type: Article

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