Modified starch (cationized)-alginate beads containing aceclofenac: Formulation optimization using central composite design

Starch/Staerke

Volumn 65, Issue 7-8, 2013, Pages 603-612

  Malakar, Jadupati ^a   Nayak, Amit Kumar ^b   Das, Arindam ^a  

^a West Bengal University of Technology   (India)

^b SEEMANTA INSTITUTE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Aceclofenac; Cationized starch; Central composite design; Sodium alginate; Sustained release

Indexed keywords

ACECLOFENAC; CATIONIZED STARCH; CENTRAL COMPOSITE DESIGNS; DRUG ENCAPSULATION EFFICIENCY; FORMULATION OPTIMIZATION; POWDER X RAY DIFFRACTION; SCANNING ELECTRON MICROSCOPE; SUSTAINED RELEASE;

DESIGN; DISSOLUTION; DRUG PRODUCTS; ENCAPSULATION; INFRARED SPECTROSCOPY; OPTIMIZATION; SCANNING ELECTRON MICROSCOPY; SODIUM ALGINATE; X RAY DIFFRACTION;

STARCH;

EID: 84879845087     PISSN: 00389056     EISSN: 1521379X     Source Type: Journal    
DOI: 10.1002/star.201200231     Document Type: Article

References (30)

1. Herman, J., Remon, J. P., De Velder, J., Modified starches as hydrophilic matrices for controlled oral delivery. 1. Production and characterization of thermally modified starches. Int. J. Pharm. 1989, 56, 51-63.
2. Prado, H. J., Matulewicz, M. C., Bonelli, P. R., Cukierman, A. L., Preparation and characterization of a novel starch-based interpolyelectrolyte complex as matrix for controlled drug release. Carbohydr. Res. 2009, 344, 1325-1331.
3. Tay, S. H., Pang, S. C., Chin, S. F., Facile synthesis of starch-maleate monoesters from native sago starch. Carbohydr. Polym. 2012, 88, 1195-1200.
4. Pang, S. C., Chin, S. F., Tay, S. H., Tchong, F. M., Starch-maleate- polyvinyl alcohol hydrogels with controllable swelling behaviours. Carbohydr. Polym. 2011, 84, 424-429.
5. Cui, D., Liu, M., Wu, L., Bi, Y., Synthesis of potato starch sulphate and optimization of the reaction conditions. Int. J. Biol. Macromol. 2009, 44, 294-299.
6. Willett, J. L., Shogren, R. L., Processing and properties of extruded starch/polymer foams. Polymer 2002, 43, 5935-5947.
7. Raghavan, D., Emekalam, A., Characterization of starch/polyethylene and starch/polyethylene/poly (lactic acid) composites. Polym. Degrad. Stabil. 2001, 72, 509-517.
8. Zhang, L., Den, X., Zhao, S., Huang, Z., Biodegradable polymer blends of poly (3-hydroxybutyrate) and starch acetate. Polym. Int. 1997, 44, 104-110.
9. Pohja, S., Suihko, E., Vidgren, M., Paronen, P., Ketolainen, J., Starch acetate as a tablet matrix for sustained drug release. J. Control. Release 2004, 94, 293-302.
10. Rahmouni, M., Chouinard, F., Nekka, F., Lenaerts, V., Leroux, J. C., Enzymatic degradation of cross-linked high amylose starch tablets and its effect on in vitro release of sodium diclofenac. Eur. J. Pharm. Biopharm. 2001, 51, 191-198.
11. O'Brien, S., Wang, Y., Vervaet, C., Remon, J. P., Starch phosphates prepared by reactive extrusion as sustained release agent. Carbohydr. Polym. 2009, 76, 557-566.
12. Wang, Q., Hu, X., Du, Y., Kenedy, J. F., Alginate/starch blend fibers and their properties for drug controlled release, Carbohydr. Polym. 2010, 82, 842-847.
13. Kim, Y. J., Park, H. G., Yang, Y. L., Yoon, Y., et al., Multifuctional drug delivery system using starch-alginate beads for controlled release. Biol. Pharm. Bull. 2005, 28, 394-397.
14. Jha, A. K., Bhattacharya, A., Preparation and in vitro evaluation of sweet potato starch blended sodium alginate microbeads. Adv. Nat. Appl. Sci. 2008, 2, 122-128.
15. Sachan, N. K., Bhattacharya, A., Modeling and characterization of drug release from glutinous rice starch based hydrogel beads for controlled drug delivery. Int. J. Health Res. 2009, 2, 93-99.
16. Soares, G. A., de Castro, A. D., Cury, B. S. F., Evangelista, R. C., Blends of cross-linked high amylase starch/pectin loaded with diclofenac. Carbohydr. Polym. 2013, 91, 135-142.
17. Xie, X., Liu, Q., Cui, S. W., in:, Cui, S. W., (Ed.), Food Carbohydrates: Chemistry, Physical Properties, and Applications, CRC Press, Boca Raton, FL 2005, pp. 357-406.
18. Rutkaite, R., Bendoraitiene, J., Khimaviciute, R., Zemaitaitis, R., Cationic starch nanoparticles based on polyelectrolyte complexes. Int. J. Biol. Macromol. 2012, 50, 687-693.
19. Pal, S., Mal, D., Singh, R. P., Cationic starch: an effective flocculating agent. Carbohydr. Polym. 2005, 59, 417-423.
20. Kuo, W.-Y., Lai, H.-M., Effects of reaction conditions on the physicochemical properties of cationic starch studied by RSM. Carbohydr. Polym. 2009, 75, 627-635.
21. Nayak, A. K., Khatua, S., Hasanin, M. S., Sen, K. K., Development of alginate-PVP K 30 microbeads for controlled diclofenac sodium delivery using central composite design. DARU J. Pharm. Sci. 2011, 19, 356-366.
22. Pal, D., Nayak, A. K., Development, optimization, and anti-diabetic activity of gliclazide-loaded alginate-methyl cellulose mucoadhesive microcapsules. AAPS PharmSci.Tech. 2011, 12, 1431-1441.
23. Singh, B., Sharma, V., Chauhan, D., Gastroretentive floating sterculia-alginate beads for use in antiulcer drug delivery. Chem. Eng. Res. Des. 2010, 88, 997-1012.
24. 2+ crosslinking and freeze-thawing cycles for controlled release diclofenac sodium. Int. J. Biol. Macromol. 2010, 46, 517-523.
25. Nayak, A. K., Pal, D., Development of pH-sensitive tamarind seed polysaccharide-alginate composite beads for controlled diclofenac sodium delivery using response surface methodology. Int. J. Biol. Macromol. 2011, 49, 784-793.
26. Pal, D., Nayak, A. K., Novel tamarind seed polysaccharide-alginate mucoadhesive microspheres for oral gliclazide delivery: In vitro in vivo evaluation. Drug Deliv. 2012, 19, 123-131.
27. Chakraborty, S., Khandai, M., Sharma, A., Khanam, N., et al., Preparation, in vitro and in vivo evaluation of algino-pectinate bioadhesive microspheres: an investigation of the effects of polymers using multiple comparison analysis. Acta Pharm. 2010, 60, 255-266.
28. Yadav, A. V., Shete, A. S., Dabke, A. P., Formulation and evaluation of orodispersible liquisolid compacts of aceclofenac. Indian J. Pharm. Educ. Res. 2010, 44, 227-235.
29. Malakar, J., Nayak, A. K., Pal, D., Development of cloxacillin loaded multiple-unit alginate-based floating system by emulsion-gelation method. Int. J. Biol. Macromol. 2012, 50, 138-147.
30. Nayak, A. K., Das, B., Maji, R., Calcium alginate/gum Arabic beads containing glibenclamide: development and in vitro characterization. Int. J. Biol. Macromol. 2012, 51, 1070-1078.