Sequential extraction of amphetamines, opiates, and 11-nor- Δ9-tetrahydrocannabinol-9-carboxylic acid from a limited volume of urine using a monolithic silica spin column coupled with gas chromatography-mass spectrometry

Forensic Toxicology

Volumn 31, Issue 2, 2013, Pages 312-321

  Namera, Akira ^a   Saito, Takeshi ^b   Miyazaki, Shota ^c   Ohta, Shigenori ^c   Oikawa, Hiroshi ^c   Torikoshi, Aiko ^a   Shiraishi, Hiroaki ^a   Nagao, Masataka ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c GL SCIENCES INC   (Japan)

Author keywords

Derivatization; Drug analysis; Gas chromatography mass spectrometry; Monolithic silica; Sample preparation

Indexed keywords

ACETIC ACID DERIVATIVE; AMPHETAMINE DERIVATIVE; CHLOROTRIMETHYLSILANE; METHANOL; N METHYL BIS(TRIFLUOROACETAMIDE); N,O BIS(RIMETHYLSILYL)TRIFLUOROACETAMIDE; NITROGEN; OPIATE DERIVATIVE; TETRAHYDROCANNABINOLIC ACID; TRIFLUOROACETAMIDE DERIVATIVE; TRIFLUOROACETYL DERIVATIVE; TRIMETHYLSILYL DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CALIBRATION; CENTRIFUGATION; CORRELATION COEFFICIENT; ELUTION; EXTRACTION AND EXTRACTS; HUMAN; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LINEAR SYSTEM; MASS FRAGMENTOGRAPHY; PH; PRIORITY JOURNAL; URINALYSIS;

OPIS;

EID: 84879793247     PISSN: 18608965     EISSN: 18608973     Source Type: Journal    
DOI: 10.1007/s11419-013-0185-6     Document Type: Article

References (30)

1. McDowall RD (1989) Sample preparation for biomedical analysis. J Chromatogr B 492:3-58
2. Chang MS, Ji Q, Zhang J, El-Shourbagy TA (2007) Historical review of sample preparation for chromatographic bioanalysis: pros and cons. Drug Develop Res 68:107-133
3. Kole PL, Venkatesh G, Kotecha J, Sheshala R (2011) Recent advances in sample preparation techniques for effective bioanalytical methods. Biomed Chromatogr 25:199-217
4. Namera A, Nakamoto A, Saito T, Nagao M (2011) Colorimetric detection and chromatographic analyses of designer drugs in biological materials: a comprehensive review. Forensic Toxicol 29:1-24
5. El-Haj BM, Ali HS, Hamoudi NM (2011) Oripavine as a new marker of opiate product use. Forensic Toxicol 29:152-158
6. Murphy MA, Huestis MA (2005) LC-ESI-MS/MS analysis for the quantification of morphine, codeine, morphine-3-β-D-glucuronide, morphine-6-β-D- glucuronide, and codeine-6-β-D-glucuronide in human urine. J Mass Spectrom 40:1412-1416
7. Shima N, Katagi M, Kamata H, Zaitsu K, Kamata T, Miki A, Tsuchihashi H, Sakuma T, Nemoto N (2008) Conjugates of p-hydroxymethamphetamine and 4-hydroxy-3-methoxymethamphetamine in blood obtained from methamphetamine and 3,4-methylenedioxymethamphetamine users: analysis by LC-MS-MS. Forensic Toxicol 26:58-65
8. Kłys M, Rojek S (2008) Four nonfatal and six fatal cases of opiate use: utility of morphine, its metabolites, and their ratios in blood specimens. Forensic Toxicol 26:87-90
9. Felli M, Martello S, Chiarotti M (2011) LC-MS-MS method for simultaneous determination of THCCOOH and THCCOOH-glucuronide in urine: application to workplace confirmation tests. Forensic Sci Int 204:67-73
10. Deventer K, Pozo OJ, Delbeke FT, Van Eenoo P (2012) Direct quantification of morphine glucuronides and free morphine in urine by liquid chromatography-tandem mass spectrometry. Forensic Toxicol 30:106-113
11. Namera A, Nakamoto A, Nishida M, Saito T, Kishiyama I, Miyazaki S, Yahata M, Yashiki M, Nagao M (2008) Extraction of amphetamines and methylenedioxyamphetamines from urine using a monolithic silica disk-packed spin column and high-performance liquid chromatography-diode array detection. J Chromatogr A 1208:71-75
12. Saito T, Yamamoto R, Inoue S, Kishiyama I, Miyazaki S, Nakamoto A, Nishida M, Namera A, Inokuchi S (2008) Simultaneous determination of amitraz and its metabolite in human serum by monolithic silica spin column extraction and liquid chromatography-mass spectrometry. J Chromatogr B 867:99-104
13. Saito T, Miura N, Namera A, Oikawa H, Miyazaki S, Nakamoto A, Inokuchi S (2012) Mixed-mode C-C18 monolithic spin-column extraction and GC-MS for simultaneous assay of organophosphorus compounds, glyphosate, and glufosinate in human serum and urine. Forensic Toxicol 30:1-10
14. Nakanishi K (1997) Pore structure control of silica gels based on phase separation. J Porous Mater 4:67-112
15. Miyazaki S, Yamada T, Ohta S, Saito T, Namera A, Ohira M (2010) Rapid preparation methods of biological samples for ionic compounds using ion exchange type monolithic silica spin column (in Japanese). Bunseki Kagaku 59:213-218
16. Delbeke FT, Debackere M (1993) Influence of hydrolysis procedures on the urinary concentrations of codeine and morphine in relation to doping analysis. J Pharm Biomed Anal 11:339-343
17. Chen ZR, Somogyi AA, Reynolds G, Bochner F (1991) Disposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers. Br J Clin Pharmacol 31:381-390
18. Harvey DJ, Paton WDM (1984) Metabolism of the cannabinoids. Rev Biochem Toxicol 6:221-264
19. Kelly P, Jones RT (1992) Metabolism of tetrahydrocannabinol in frequent and infrequent marijuana users. J Anal Toxicol 16:228-235
20. Raharjo TJ, Verpoorte R (2004) Methods for the analysis of cannabinoids in biological materials: a review. Phytochem Anal 15:79-94
21. Williams PL, Moffat AC (1980) Identification in human urine of Δ9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite. J Pharm Pharmacol 32:445-448
22. Kemp PM, Abukhalaf IK, Manno JE, Manno BR, Alford DD, McWilliams ME, Nixon FE, Fitzgerald MJ, Reeves RR, Wood MJ (1995) Cannabinoids in humans. II. The influence of three methods of hydrolysis on the concentration of THC and two metabolites in urine. J Anal Toxicol 19:292-298
23. Kramer E, Kovar KA (1999) On-line coupling of automated solid-phase extraction with high-performance liquid chromatography and electrochemical detection: quantitation of oxidizable drugs of abuse and their metabolites in plasma and urine. J Chromatogr 731:167-177
24. 9-tetrahydrocannabinol in human urine following tandem enzyme-Alkaline hydrolysis. J Anal Toxicol 31:477-485
25. Ranieri TL, Ciolino LA (2008) Rapid selective screening and determination of ephedrine alkaloids using GC-MS footnote mark. Phytochem Anal 19:127-135
26. Guidance for Industry Bioanalytical Method Validation. http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/ Guidances/ucm070107.pdf. Accessed 6 December 2012
27. Namera A, Yamamoto S, Saito T, Miyazaki S, Oikawa H, Nakamoto A, Nagao M (2011) Simultaneous extraction of acidic and basic drugs from urine using mixed-mode monolithic silica spin column bonded with octadecyl and cation-exchange group. J Sep Sci 34:2232-2239
28. Namera A, Nakamoto A, Miyazaki S, Yui Y, Saito T, Nagao M (2011) Monolithic spin column: a new extraction device for analysis of drugs in urine and serum by GC-MS and HPLC-MS. J AOAC Int 94:765-774
29. Valente MJ, Carvalho F, Bastos ML, Carvalho M, De Pinho PG (2010) Development and validation of a gas chromatography/ion trap-mass spectrometry method for simultaneous quantification of cocaine and its metabolites benzoylecgonine and norcocaine: application to the study of cocaine metabolism in human primary cultured renal cells. J Chromatogr B 878:3083-3088
30. Ellison ST, Brewer WE, Morgan SL (2009) Comprehensive analysis of drugs of abuse in urine using disposable pipette extraction. J Anal Toxicol 33:356-365