Oripavine as a new marker of opiate product use

Forensic Toxicology

Volumn 29, Issue 2, 2011, Pages 152-158

  El Haj, Babiker M ^a   Ali, Heyam S ^b   Hamoudi, Nehad M ^c  

^a AJMAN UNIVERSITY   (United Arab Emirates)

^b DUBAI PHARMACY COLLEGE   (United Arab Emirates)

^c GULF MEDICAL UNIVERSITY   (United Arab Emirates)

Author keywords

GC MS; Marker of opiate product use; Opium; Oripavine; Poppy seed; Thebaine metabolism

Indexed keywords

ACETIC ANHYDRIDE; ACID ANHYDRIDE; CHLOROTRIMETHYLSILANE; CODEINE; DIAMORPHINE; MORPHINE; ORIPAVINE; PROPIONIC ACID ANHYDRIDE; THEBAINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DEMETHYLATION; DERIVATIZATION; DRUG URINE LEVEL; HUMAN; HYDROLYSIS; MASS FRAGMENTOGRAPHY; PRIORITY JOURNAL; URINALYSIS;

PAPAVER;

EID: 79960602131     PISSN: 18608965     EISSN: 18608973     Source Type: Journal    
DOI: 10.1007/s11419-011-0117-2     Document Type: Article

References (21)

1. K Kudo T Ishida W Hikiji M Hayashida K Uekusa Y Usumoto A Tsuji N Ikeda 2009 Construction of calibration-locking databases for rapid and reliable drug screening by gas chromatography-mass spectrometry Forensic Toxicol 27 21 31 10.1007/s11419-009-0066-1 1:CAS:528:DC%2BD1MXitlGgtLs%3D
2. K Kudo T Ishida W Hikiji Y Usumoto T Umehara K Nagamatsu A Tsuji N Ikeda 2010 Pattern of poisoning in Japan: selection of drugs and poisons for systematic toxicological analysis Forensic Toxicol 28 25 32 10.1007/s11419-009- 0088-8 1:CAS:528:DC%2BC3cXhtleit7g%3D
3. AM Al-Amri RM Smith BM El-Haj MH Juma'a 2004 GC-MS detection and characterization of reticuline as opium use marker Forensic Sci Int 142 61 69 15272474 10.1016/j.forsciint.2004.02.006 1:STN:280:DC%2BD2czmvFyhtg%3D%3D (Pubitemid 38510575)
4. AM Al-Amri RM Smith BM El-Haj 2005 The GC-MS detection and characterization of neopine resulting from opium use and codeine metabolism and its potential as an opiate-product-use marker Anal Bioanal Chem 382 830 835 15782326 10.1007/s00216-005-3168-6 1:CAS:528:DC%2BD2MXkslSrsLo%3D (Pubitemid 40891014)
5. BM El-Haj AM Al-Amri HS Ali I Ahmed 2007 GC-MS detection and characterization of thebaine as a urinary marker of opium use Forensic Toxicol 25 62 68 10.1007/s11419-007-0028-4 1:CAS:528:DC%2BD1cXhs1yms7k%3D
6. BM El-Haj AM Al-Amri HS Ali 2007 GC-MS detection and tentative characterization of two noscapine metabolites and their potential as markers for opium and illicit heroin use Forensic Toxicol 25 22 29 10.1007/s11419-007-0023- 9 1:CAS:528:DC%2BD2sXotleksLs%3D (Pubitemid 46855433)
7. 6-monoacetylmorphine in urine samples by GC-MS as evidence for heroin use J Anal Toxicol 9 134 138 3892162 1:CAS:528:DyaL2MXksV2htr0%3D (Pubitemid 15118279)
8. R Brenneisen F Hasler D Wursch 2002 Acetylcodeine as a urinary marker to differentiate the use of street heroin and pharmaceutical heroin J Anal Toxicol 26 561 566 12501913 1:CAS:528:DC%2BD38XpsVOrsb8%3D (Pubitemid 35453746)
9. M Bogusz 2001 Detection of non-prescription heroin markers in urine with liquid chromatography-atmospheric pressure chemical ionization mass spectrometry J Anal Toxicol 25 431 438 11550816 1:CAS:528:DC%2BD3MXmsVeis7s%3D (Pubitemid 32786545)
10. N Mclachlan-Troup G Taylor B Trathen 2001 Diamorphine treatment for opiate dependence: putative markers of concomitant heroin misuse Addict Biol 6 223 231 11900600 10.1080/13556210120056553 1:CAS:528:DC%2BD3MXlvFKqtLY%3D (Pubitemid 32675403)
11. Baselt R (2004) Disposition of toxic drugs and chemicals in man, 7th edn. Biomedical Publications, Foster City, pp 262-265, 759-762
12. H ElSohly D Stanford A Jones M ElSohly H Snyder C Pedersen 1988 Gas chromatographic/mass spectrometric analysis of morphine and codeine in human urine of poppy seed eaters J Forensic Sci 33 347 355 3373154 1:CAS:528:DyaL1cXhvVWls70%3D
13. G Cassella A Wu B Shaw D Hill 1997 The analysis of thebaine in urine for the detection of poppy seed consumption J Anal Toxicol 21 376 383 9288591 1:CAS:528:DyaK2sXlvF2ku7c%3D (Pubitemid 27391400)
14. R Lewis R Johnson R Hattrup 2005 Simultaneous detection of theabine, 6-MAM, and six abused opiates in postmortem fluids and tissues using Zymark automated solid-phase extraction and gas chromatography-mass spectrometry J Chromatogr B 822 137 145 10.1016/j.jchromb.2005.05.031 1:CAS:528: DC%2BD2MXmsVOnu70%3D (Pubitemid 40994045)
15. C Meadway S George R Braithwaite 1998 Opiate concentration following the ingestion of poppy-seed products-evidence for the poppy-seed defense Forensic Sci Int 96 29 38 9800363 10.1016/S0379-0738(98)00107-8 1:STN:280: DyaK1M%2Fhs1Ontw%3D%3D (Pubitemid 28434912)
16. Y Yamazoe H Numata T Yanagita 1981 Thebaine metabolites in the urine of rhesus monkeys Jpn J Pharmacol 31 433 442 7311155 10.1254/jjp.31.433 1:CAS:528:DyaL3MXltVygtr4%3D (Pubitemid 11072688)
17. W Chen H Wu D Bernard MD Metcalf JR. Deschamp JL Flippen-Anderson AD MacKerell Jr. A Coop 2003 Rearrangement of 5-trimethylsilylthebaine on treatment with L-selectride: an efficient synthesis of (+)-bractazonine J Org Chem 68 1929 1932 12608812 10.1021/jo020704m 1:CAS:528:DC%2BD3sXpvVarug%3D%3D (Pubitemid 36504849)
18. L Odella S McCluskey 2008 Isolation and identification of unique marker compounds from the Tasmanian poppy Papaver somniferum N. Implications for the identification of illicit heroin of Tasmanian origin Forensic Sci Int 175 202 208 10.1016/j.forsciint.2007.07.002 (Pubitemid 351210693)
19. Merck & Co. (2001) The Merck Index, 13th edn. Whitehouse Station NJ, entry 6994
20. G Mikus A Somogyi F Bochner M Eichelbaum 1991 Thebaine-O-demethylation to oripavine: genetic differences between two rats strains Xenobiotica 21 1501 1509 1763524 10.3109/00498259109044400 1:CAS:528:DyaK38XhsFaqtQ%3D%3D
21. Manske R, Holmes H (1952) The chemistry of alkaloids. Academic Press, New York