Norepinephrine Inhibits Macrophage Migration by Decreasing CCR2 Expression

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Xiu, Fangming ^a   Stanojcic, Mile ^a   Jeschke, Marc G ^a  

^a Sunnybrook Health Sciences Centre   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD11B ANTIBODY; CD11B ANTIGEN; CHEMOKINE RECEPTOR CCR2; COLONY STIMULATING FACTOR; DEXTRAN; F4 80 ANTIBODY; FLUORESCEIN ISOTHIOCYANATE; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MHC II ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; NORADRENALIN; TRANSCRIPTION FACTOR MAFB; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CELL ASSAY; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNOPATHOLOGY; IMMUNOREGULATION; IN VITRO STUDY; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MACROPHAGE MIGRATION; MACROPHAGE MIGRATION INHIBITION; MOUSE; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

ANIMALS; ANTIGENS, CD11B; ANTIGENS, DIFFERENTIATION; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS II; LIPOPOLYSACCHARIDES; MACROPHAGES; MAFB TRANSCRIPTION FACTOR; MICE; MICE, INBRED C57BL; NOREPINEPHRINE; PHAGOCYTOSIS; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RECEPTORS, CCR2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84879755954     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069167     Document Type: Article

References (40)

1. Koo DJ, Chaudry IH, Wang P, (2000) Mechanism of hepatocellular dysfunction during sepsis: the role of gut-derived norepinephrine (review). Int J Mol Med,5: 457-465. PubMed: 10762647.
2. Church D, Elsayed S, Reid O, Winston B, Lindsay R, (2006) Burn wound infections. Clin Microbiol Rev,19: 403-434. doi:10.1128/CMR.19.2.403-434.2006. PubMed: 16614255.
3. Kraft R, Herndon DN, Al-Mousawi AM, Williams FN, Finnerty CC, et al. (2012) Burn size and survival probability in paediatric patients in modern burn care: a prospective observational cohort study. Lancet,379: 1013-1021. doi:10.1016/S0140-6736(11)61345-7. PubMed: 22296810.
4. Jeschke MG, Mlcak RP, Finnerty CC, Norbury WB, Gauglitz GG, et al. (2007) Burn size determines the inflammatory and hypermetabolic response. Crit Care,11: R90. doi:10.1186/cc5877. PubMed: 17716366.
5. Kulp GA, Herndon DN, Lee JO, Suman OE, Jeschke MG, (2010) Extent and magnitude of catecholamine surge in pediatric burned patients. Shock,33: 369-374. doi:10.1097/SHK.0b013e3181b92340. PubMed: 20407405.
6. Jeschke MG, Gauglitz GG, Kulp GA, Finnerty CC, Williams FN, et al. (2011) Long-term persistance of the pathophysiologic response to severe burn injury. PLOS ONE,6: e21245. doi:10.1371/journal.pone.0021245. PubMed: 21789167.
7. Tang Y, Shankar R, Gamboa M, Desai S, Gamelli RL, et al. (2001) Norepinephrine modulates myelopoiesis after experimental thermal injury with sepsis. Ann Surg,233: 266-275. doi:10.1097/00000658-200102000-00017. PubMed: 11176134.
8. Howell K, Posluszny J, He LK, Szilagyi A, Halerz J, et al. (2012) High MafB expression following burn augments monocyte commitment and inhibits DC differentiation in hemopoietic progenitors. J Leukoc Biol,91: 69-81. doi:10.1189/jlb.0711338. PubMed: 21984745.
9. Santangelo S, Gamelli RL, Shankar R, (2001) Myeloid commitment shifts toward monocytopoiesis after thermal injury and sepsis. Ann Surg,233: 97-106. doi:10.1097/00000658-200101000-00015. PubMed: 11141231.
10. Schwacha MG, (2003) Macrophages and post-burn immune dysfunction. Burns,29: 1-14. doi:10.1016/S0305-4179(02)00187-0. PubMed: 12543039.
11. Cohen MJ, Shankar R, Stevenson J, Fernandez R, Gamelli RL, et al. (2004) Bone marrow norepinephrine mediates development of functionally different macrophages after thermal injury and sepsis. Ann Surg,240: 132-141. doi:10.1097/01.sla.0000130724.84914.d6. PubMed: 15213629.
12. Gosain A, Muthu K, Gamelli RL, DiPietro LA, (2007) Norepinephrine suppresses wound macrophage phagocytic efficiency through alpha- and beta-adrenoreceptor dependent pathways. Surgery,142: 170-179. doi:10.1016/j.surg.2007.04.015. PubMed: 17689682.
13. Muthu K, He LK, Szilagyi A, Strotmon P, Gamelli RL, et al. (2010) ss-adrenergic stimulation increases macrophage CD14 expression and E. coli phagocytosis through PKA signaling mechanisms. J Leukoc Biol,88: 715-724. doi:10.1189/jlb.0410186. PubMed: 20643814.
14. Baccan GC, Sesti-Costa R, Chedraoui-Silva S, Mantovani B, (2010) Effects of cold stress, corticosterone and catecholamines on phagocytosis in mice: differences between resting and activated macrophages. Neuroimmunomodulation,17: 379-385. doi:10.1159/000292058. PubMed: 20516719.
15. Szelényi J, Kiss JP, Vizi ES, (2000) Differential involvement of sympathetic nervous system and immune system in the modulation of TNF-alpha production by alpha2- and beta-adrenoceptors in mice. J Neuroimmunol,103: 34-40. doi:10.1016/S0165-5728(99)00234-9. PubMed: 10674987.
16. Spengler RN, Allen RM, Remick DG, Strieter RM, Kunkel SL, (1990) Stimulation of alpha-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor. J Immunol,145: 1430-1434. PubMed: 2166759.
17. Hu XX, Goldmuntz EA, Brosnan CF, (1991) The effect of norepinephrine on endotoxin-mediated macrophage activation. J Neuroimmunol,31: 35-42. doi:10.1016/0165-5728(91)90084-K. PubMed: 1845768.
18. Deng J, Muthu K, Gamelli R, Shankar R, Jones SB, (2004) Adrenergic modulation of splenic macrophage cytokine release in polymicrobial sepsis. Am J Physiol Cell Physiol,287: C730-C736. doi:10.1152/ajpcell.00562.2003. PubMed: 15151906.
19. Clover AJ, Kumar AH, Caplice NM, (2011) Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis. Burns,37: 1386-1393. doi:10.1016/j.burns.2011.08.001. PubMed: 21924836.
20. Souto FO, Alves-Filho JC, Turato WM, Auxiliadora-Martins M, Basile-Filho A, et al. (2011) Essential role of CCR2 in neutrophil tissue infiltration and multiple organ dysfunction in sepsis. Am J Respir Crit Care Med,183: 234-242. doi:10.1164/rccm.201003-0416OC. PubMed: 20732989.
21. Kapoor A, Thiemermann C, (2011) Targeting CCR2: a novel therapeutic strategy for septic shock? Am J Respir Crit Care Med,183: 150-151. doi:10.1164/rccm.201009-1403ED. PubMed: 21242593.
22. Weischenfeldt J, Porse B, (2008) Bone Marrow-Derived Macrophages (BMM): Isolation and Applications. CSH Protoc,(2008): pdb prot5080.
23. Engel DR, Maurer J, Tittel AP, Weisheit C, Cavlar T, et al. (2008) CCR2 mediates homeostatic and inflammatory release of Gr1(high) monocytes from the bone marrow, but is dispensable for bladder infiltration in bacterial urinary tract infection. J Immunol,181: 5579-5586. PubMed: 18832716.
24. Tsou CL, Peters W, Si Y, Slaymaker S, Aslanian AM, et al. (2007) Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J Clin Invest,117: 902-909. doi:10.1172/JCI29919. PubMed: 17364026.
25. Sica A, Saccani A, Borsatti A, Power CA, Wells TN, et al. (1997) Bacterial lipopolysaccharide rapidly inhibits expression of C-C chemokine receptors in human monocytes. J Exp Med,185: 969-974. doi:10.1084/jem.185.5.969. PubMed: 9120403.
26. Yi L, Chandrasekaran P, Venkatesan S, (2012) TLR signaling paralyzes monocyte chemotaxis through synergized effects of p38 MAPK and global Rap-1 activation. PLOS ONE,7: e30404. doi:10.1371/journal.pone.0030404. PubMed: 22347375.
27. Maejima K, Deitch EA, Berg RD, (1984) Bacterial translocation from the gastrointestinal tracts of rats receiving thermal injury. Infect Immun,43: 6-10. PubMed: 6360909.
28. Kelly LM, Englmeier U, Lafon I, Sieweke MH, Graf T, (2000) MafB is an inducer of monocytic differentiation. EMBO J,19: 1987-1997. doi:10.1093/emboj/19.9.1987. PubMed: 10790365.
29. Sarrazin S, Mossadegh-Keller N, Fukao T, Aziz A, Mourcin F, et al. (2009) MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells. Cell,138: 300-313. doi:10.1016/j.cell.2009.04.057. PubMed: 19632180.
30. Gosain A, Gamelli RL, DiPietro LA, (2009) Norepinephrine-mediated suppression of phagocytosis by wound neutrophils. J Surg Res,152: 311-318. doi:10.1016/j.jss.2008.05.001. PubMed: 18952237.
31. Sesti-Costa R, Baccan GC, Chedraoui-Silva S, Mantovani B, (2010) Effects of acute cold stress on phagocytosis of apoptotic cells: the role of corticosterone. Neuroimmunomodulation,17: 79-87. doi:10.1159/000258690. PubMed: 19923852.
32. Kelly JL, O'Sullivan C, O'Riordain M, O'Riordain D, Lyons A, et al. (1997) Is circulating endotoxin the trigger for the systemic inflammatory response syndrome seen after injury? Ann Surg,225: 530-541. doi:10.1097/00000658-199705000-00010. PubMed: 9193181.
33. Zhou Y, Yang Y, Warr G, Bravo R, (1999) LPS down-regulates the expression of chemokine receptor CCR2 in mice and abolishes macrophage infiltration in acute inflammation. J Leukoc Biol,65: 265-269. PubMed: 10088610.
34. Williams JG, Bankey P, Minei JP, McIntyre K, Turbeville T, (1994) Burn injury enhances alveolar macrophage endotoxin sensitivity. J Burn Care Rehabil,15: 493-498. doi:10.1097/00004630-199411000-00006. PubMed: 7852452.
35. Enomoto N, Takei Y, Yamashina S, Fukuda T, Suzuki S, et al. (2004) Burn injury sensitizes rat Kupffer cells via mechanisms dependent on gut-derived endotoxin. J Gastroenterol,39: 1175-1181. doi:10.1007/s00535-004-1468-9. PubMed: 15622482.
36. Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, et al. (2010) Development of monocytes, macrophages, and dendritic cells. Science,327: 656-661. doi:10.1126/science.1178331. PubMed: 20133564.
37. Rodriguez S, Chora A, Goumnerov B, Mumaw C, Goebel WS, et al. (2009) Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis. Blood,114: 4064-4076. doi:10.1182/blood-2009-04-214916. PubMed: 19696201.
38. Scumpia PO, Kelly-Scumpia KM, Delano MJ, Weinstein JS, Cuenca AG, et al. (2010) Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling. J Immunol,184: 2247-2251. doi:10.4049/jimmunol.0903652. PubMed: 20130216.
39. King KY, Goodell MA, (2011) Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat Rev Immunol,11: 685-692. doi:10.1038/nri3062. PubMed: 21904387.
40. Muthu K, He LK, Melstrom K, Szilagyi A, Gamelli RL, et al. (2008) Perturbed bone marrow monocyte development following burn injury and sepsis promote hyporesponsive monocytes. J Burn Care Res,29: 12-21. PubMed: 18182893.