Reversion of a fungal genetic code alteration links proteome instability with genomic and phenotypic diversification

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 27, 2013, Pages 11079-11084

  Bezerra, Ana R ^a   Simões, João ^a   Lee, Wanseon ^b   Rung, Johan ^b   Weil, Tobias ^a   Gut, Ivo G ^c   Gut, Marta ^c   Bayés, Mónica ^c   Rizzetto, Lisa ^d   Cavalieri, Duccio ^d,e   Giovannini, Gloria ^f   Bozza, Silvia ^f   Romani, Luigina ^f   Kapushesky, Misha ^b   Moura, Gabriela R ^a   Santos, Manuel A S ^a  

^a UNIVERSITY OF AVEIRO   (Portugal)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c National Institute of Bioinformatics   (Spain)

^d RESEARCH AND INNOVATION CENTRE   (Italy)

^e UNIVERSITY OF FLORENCE   (Italy)

^f UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Codon reassignment; Evolution; tRNA

Indexed keywords

LEUCINE; PROTEOME; SERINE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFUNGAL RESISTANCE; ARTICLE; CANDIDA ALBICANS; CHROMOSOME; CODON; CONTROLLED STUDY; FUNGAL COLONIZATION; FUNGAL GENOME; FUNGAL METABOLISM; FUNGAL STRAIN; FUNGAL STRUCTURES; FUNGUS GROWTH; GENE SEQUENCE; GENETIC CODE; GENETIC ENGINEERING; GENOME ANALYSIS; GENOTYPE; GROWTH RATE; HETEROZYGOSITY LOSS; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; MOUSE; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN STABILITY; RNA TRANSLATION; SINGLE NUCLEOTIDE POLYMORPHISM;

CODON REASSIGNMENT; EVOLUTION; TRNA;

ANIMALS; CANDIDA ALBICANS; CODON; DENDRITIC CELLS; EVOLUTION, MOLECULAR; FEMALE; FUNGAL PROTEINS; GENETIC CODE; GENETIC VARIATION; GENOME, FUNGAL; GENOMIC INSTABILITY; HETEROZYGOTE DETECTION; HUMANS; MICE; MICE, INBRED C57BL; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEOME; RNA, FUNGAL;

CANDIDA ALBICANS; FUNGI;

EID: 84879727622     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1302094110     Document Type: Article

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