메뉴 건너뛰기




Volumn 36, Issue 2, 2013, Pages 185-192

Bromelain purification through unconventional aqueous two-phase system (PEG/ammonium sulphate)

Author keywords

Ammonium sulphate; Bromelain; Pineapple; Poly(ethylene glycol); Unconventional aqueous two phase systems

Indexed keywords

AMMONIUM SULPHATE; AQUEOUS TWO PHASE SYSTEM; CONVENTIONAL SYSTEMS; FRACTIONAL PRECIPITATION; LIQUID-LIQUID EXTRACTION; PINEAPPLE; PURIFICATION FACTORS; RESPONSE SURFACE METHODOLOGY;

EID: 84879725810     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-012-0774-5     Document Type: Article
Times cited : (39)

References (31)
  • 2
    • 58149199032 scopus 로고    scopus 로고
    • Extraction and purification of ipomoea peroxidase employing three-phase partitioning
    • 10.1007/s12010-008-8185-4 10.1007/s12010-008-8185-4 1:CAS:528: DC%2BD1cXhsVSitLfE
    • Narayan A, Madhusudhan M, Raghavarao K (2008) Extraction and purification of ipomoea peroxidase employing three-phase partitioning. Appl Biochem Biotechnol 151(2):263-272. doi: 10.1007/s12010-008-8185-4
    • (2008) Appl Biochem Biotechnol , vol.151 , Issue.2 , pp. 263-272
    • Narayan, A.1    Madhusudhan, M.2    Raghavarao, K.3
  • 3
    • 0003578648 scopus 로고
    • Aqueous two-phase partitioning - Physical chemistry and bioanalytical applications
    • 694-694
    • Zaslavsky BY (1995) Aqueous two-phase partitioning - physical chemistry and bioanalytical applications. Ber Bunsenges Phys Chem 99(4):221-290, 694-694
    • (1995) Ber Bunsenges Phys Chem , vol.99 , Issue.4 , pp. 221-290
    • Zaslavsky, B.Y.1
  • 5
    • 79952858023 scopus 로고    scopus 로고
    • The effect of pH on bromelain partition from Ananas comosus by PEG4000/phosphate ATPS
    • 10.1590/S1516-89132011000100017 1:CAS:528:DC%2BC3MXpvFSlt7g%3D
    • Ferreira JF, Santana JCC, Tambourgi EB (2011) The effect of pH on bromelain partition from Ananas comosus by PEG4000/phosphate ATPS. Braz Arch Biol Technol 54:125-132
    • (2011) Braz Arch Biol Technol , vol.54 , pp. 125-132
    • Ferreira, J.F.1    Santana, J.C.C.2    Tambourgi, E.B.3
  • 6
    • 63449139510 scopus 로고    scopus 로고
    • Expanded bed adsorption of bromelain (E.C. 3.4.22.33) from Ananas comosus crude extract
    • 10.1590/S0104-66322009000100014 1:CAS:528:DC%2BD1MXjvVygtbY%3D
    • Silveira E, Souza-Jr ME, Santana JCC, Chaves AC, Porto LF, Tambourgi EB (2009) Expanded bed adsorption of bromelain (E.C. 3.4.22.33) from Ananas comosus crude extract. Braz J Chem Eng 26:149-157
    • (2009) Braz J Chem Eng , vol.26 , pp. 149-157
    • Silveira, E.1    Souza Jr., M.E.2    Santana, J.C.C.3    Chaves, A.C.4    Porto, L.F.5    Tambourgi, E.B.6
  • 7
    • 0005919263 scopus 로고
    • Bromelain. Properties and commercial production
    • 10.1021/ie50379a028 10.1021/ie50379a028 1:CAS:528:DyaH3MXjsFOjtg%3D%3D
    • Balls AK, Thompson RR, Kies MW (1941) Bromelain. Properties and commercial production. Ind Eng Chem 33(7):950-953. doi: 10.1021/ie50379a028
    • (1941) Ind Eng Chem , vol.33 , Issue.7 , pp. 950-953
    • Balls, A.K.1    Thompson, R.R.2    Kies, M.W.3
  • 8
    • 0004608432 scopus 로고
    • Complementary enzyme actions in the clotting of milk
    • 10.1126/science.118.3077.753 10.1126/science.118.3077.753 1:CAS:528:DyaG2cXit1Witg%3D%3D
    • Heinicke RM (1953) Complementary enzyme actions in the clotting of milk. Science 118(3077):753-754. doi: 10.1126/science.118.3077.753
    • (1953) Science , vol.118 , Issue.3077 , pp. 753-754
    • Heinicke, R.M.1
  • 9
    • 0034843751 scopus 로고    scopus 로고
    • Bromelain: Biochemistry, pharmacology and medical use
    • Maurer HR (2001) Bromelain: biochemistry, pharmacology and medical use. Cell Mol Life Sci 58(9):1234-1245. doi: 10.1007/pl00000936 (Pubitemid 32850918)
    • (2001) Cellular and Molecular Life Sciences , vol.58 , Issue.9 , pp. 1234-1245
    • Maurer, H.R.1
  • 10
    • 29244447358 scopus 로고    scopus 로고
    • Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease
    • DOI 10.1016/j.cellimm.2005.10.002, PII S0008874905002376
    • Secor JER, Carson WF, Cloutier MM, Guernsey LA, Schramm CM, Wu CA, Thrall RS (2005) Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease. Cell Immunol 237(1):68-75 (Pubitemid 41821083)
    • (2005) Cellular Immunology , vol.237 , Issue.1 , pp. 68-75
    • Secor Jr., E.R.1    Carson IV, W.F.2    Cloutier, M.M.3    Guernsey, L.A.4    Schramm, C.M.5    Wu, C.A.6    Thrall, R.S.7
  • 11
    • 43949159083 scopus 로고
    • Bromelain: An immunomodulator with anticancer activity
    • 10.1016/0928-0987(94)90355-7
    • Harrach T, Garbin F, Munzig E, Eckert K, Maurer HR (1994) Bromelain: an immunomodulator with anticancer activity. Eur J Pharm Sci 2(1/2):164
    • (1994) Eur J Pharm Sci , vol.2 , Issue.12 , pp. 164
    • Harrach, T.1    Garbin, F.2    Munzig, E.3    Eckert, K.4    Maurer, H.R.5
  • 12
    • 69649084527 scopus 로고    scopus 로고
    • Cosmetic composition containing alpha hydroxyacids, salicylic acid, and enzyme mixture of bromelain and papain
    • Chatsworth OS (1996) Cosmetic composition containing alpha hydroxyacids, salicylic acid, and enzyme mixture of bromelain and papain. Biotechnol Adv 14(4):562
    • (1996) Biotechnol Adv , vol.14 , Issue.4 , pp. 562
    • Chatsworth, O.S.1
  • 13
    • 79952833209 scopus 로고    scopus 로고
    • Aqueous two-phase systems chromatography and biochemistry characterization of a enzyme from Ananas comosus
    • 1:CAS:528:DC%2BD1cXhsVyqsb3E
    • Fischer GA, Ferrari JF, Santana JCC, Fileti AMF, Tambourgi EB (2007) Aqueous two-phase systems chromatography and biochemistry characterization of a enzyme from Ananas comosus. Trend Chromatogr 3:85-95
    • (2007) Trend Chromatogr , vol.3 , pp. 85-95
    • Fischer, G.A.1    Ferrari, J.F.2    Santana, J.C.C.3    Fileti, A.M.F.4    Tambourgi, E.B.5
  • 14
  • 15
    • 77954957698 scopus 로고    scopus 로고
    • Analysis of pineapple [Ananas comosus (L.) Merr.] fruit proteinases by 2-D zymography and direct identification of the major zymographic spots by mass spectrometry
    • 10.1016/j.foodchem.2010.06.016 10.1016/j.foodchem.2010.06.016 1:CAS:528:DC%2BC3cXpt1Wqsb4%3D
    • Larocca M, Rossano R, Santamaria M, Riccio P (2010) Analysis of pineapple [Ananas comosus (L.) Merr.] fruit proteinases by 2-D zymography and direct identification of the major zymographic spots by mass spectrometry. Food Chem 123(4):1334-1342. doi: 10.1016/j.foodchem.2010.06.016
    • (2010) Food Chem , vol.123 , Issue.4 , pp. 1334-1342
    • Larocca, M.1    Rossano, R.2    Santamaria, M.3    Riccio, P.4
  • 17
    • 77953268561 scopus 로고    scopus 로고
    • Neural modeling of bromelain extraction by reversed micelles
    • 10.1590/S1516-89132010000200026 1:CAS:528:DC%2BC3cXot1eisb8%3D
    • Fileti AMF, Fischer GA, Tambourgi EB (2010) Neural modeling of bromelain extraction by reversed micelles. Braz Arch Biol Technol 53:455-463
    • (2010) Braz Arch Biol Technol , vol.53 , pp. 455-463
    • Fileti, A.M.F.1    Fischer, G.A.2    Tambourgi, E.B.3
  • 18
    • 77953408404 scopus 로고    scopus 로고
    • Batch and continuous extraction of bromelain enzyme by reversed micelles
    • 10.1590/S1516-89132009000500021 1:CAS:528:DC%2BC3cXisleitA%3D%3D
    • Fileti AMF, Fischer GA, Santana JCC, Tambourgi EB (2009) Batch and continuous extraction of bromelain enzyme by reversed micelles. Braz Arch Biol Technol 52:1225-1234
    • (2009) Braz Arch Biol Technol , vol.52 , pp. 1225-1234
    • Fileti, A.M.F.1    Fischer, G.A.2    Santana, J.C.C.3    Tambourgi, E.B.4
  • 20
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • 10.1016/0003-2697(76)90527-3 10.1016/0003-2697(76)90527-3 1:CAS:528:DyaE28XksVehtrY%3D
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72(1-2):248-254. doi: 10.1016/0003-2697(76)90527-3
    • (1976) Anal Biochem , vol.72 , Issue.1-2 , pp. 248-254
    • Bradford, M.M.1
  • 21
    • 29944442946 scopus 로고    scopus 로고
    • Production of xylanase and protease by Penicillium janthinellum CRC 87M-115 from different agricultural wastes
    • DOI 10.1016/j.biortech.2005.04.017, PII S0960852405002233
    • Oliveira LA, Porto ALF, Tambourgi EB (2006) Production of xylanase and protease by Penicillium janthinellum CRC 87M-115 from different agricultural wastes. Bioresour Technol 97(6):862-867. doi: 10.1016/j.biortech.2005.04.017 (Pubitemid 43042414)
    • (2006) Bioresource Technology , vol.97 , Issue.6 , pp. 862-867
    • Oliveira, L.A.1    Porto, A.L.F.2    Tambourgi, E.B.3
  • 22
    • 0002961944 scopus 로고
    • Precipitation techniques
    • M. Deutscher (eds) Academic Press San Diego
    • Englard S, Seifter S (1990) Precipitation techniques. In: Deutscher MP (ed) Guide to protein purification. Academic Press, San Diego
    • (1990) Guide to Protein Purification
    • Englard, S.1    Seifter, S.2
  • 25
    • 0005166241 scopus 로고    scopus 로고
    • Aqueous two-phase systems: An attractive technology for downstream processing of biomolecules
    • Gupta R, Bradoo S, Saxena RK (1999) Aqueous two-phase systems: an attractive technology for downstream processing of biomolecules. Curr Sci 77(4):520-523 (Pubitemid 129568894)
    • (1999) Current Science , vol.77 , Issue.4 , pp. 520-523
    • Gupta, R.1    Bradoo, S.2    Saxena, R.K.3
  • 28
    • 57449092421 scopus 로고    scopus 로고
    • Purification and drying of bromelain
    • 10.1016/j.seppur.2008.09.012 10.1016/j.seppur.2008.09.012 1:CAS:528:DC%2BD1cXhsFamt73J
    • Devakate RV, Patil VV, Waje SS, Thorat BN (2009) Purification and drying of bromelain. Sep Purif Technol 64(3):259-264. doi: 10.1016/j.seppur.2008.09.012
    • (2009) Sep Purif Technol , vol.64 , Issue.3 , pp. 259-264
    • Devakate, R.V.1    Patil, V.V.2    Waje, S.S.3    Thorat, B.N.4
  • 29
    • 41849130305 scopus 로고    scopus 로고
    • Use of reverse micellar systems for the extraction and purification of bromelain from pineapple wastes
    • DOI 10.1016/j.biortech.2007.09.038, PII S0960852407007845
    • Hebbar HU, Sumana B, Raghavarao KSMS (2008) Use of reverse micellar systems for the extraction and purification of bromelain from pineapple wastes. Bioresour Technol 99(11):4896-4902. doi: 10.1016/j.biortech.2007.09.038 (Pubitemid 351503828)
    • (2008) Bioresource Technology , vol.99 , Issue.11 , pp. 4896-4902
    • Umesh Hebbar, H.1    Sumana, B.2    Raghavarao, K.S.M.S.3
  • 30
    • 84860498520 scopus 로고    scopus 로고
    • Recovery of biological products in aqueous two phase systems
    • Ratanapongleka K (2010) Recovery of biological products in aqueous two phase systems. Int J Chem Eng Appl 1(2):7
    • (2010) Int J Chem Eng Appl , vol.1 , Issue.2 , pp. 7
    • Ratanapongleka, K.1
  • 31
    • 0031432125 scopus 로고    scopus 로고
    • The application of aqueous two-phase systems to the purification of pharmaceutical proteins from transgenic sheep milk
    • 10.1023/a:1007908703773 10.1023/A:1007908703773
    • Harris DP, Andrews AT, Wright G, Pyle DL, Asenjo JA (1998) The application of aqueous two-phase systems to the purification of pharmaceutical proteins from transgenic sheep milk. Bioseparation 7(1):31-37. doi: 10.1023/a:1007908703773
    • (1998) Bioseparation , vol.7 , Issue.1 , pp. 31-37
    • Harris, D.P.1    Andrews, A.T.2    Wright, G.3    Pyle, D.L.4    Asenjo, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.