Grafting of neural stem and progenitor cells to the hippocampus of young, irradiated mice causes gliosis and disrupts the granule cell layer

Cell Death and Disease

Volumn 4, Issue 4, 2013, Pages

  Sato, Y ^a,b   Shinjyo, N ^a   Sato, M ^a,c   Osato, K ^a,d   Zhu, C ^a,e   Pekna, M ^a   Kuhn, H G ^a   Blomgren, K ^a,f,g  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b NAGOYA UNIVERSITY HOSPITAL   (Japan)

^c Narita Hospital   (Japan)

^d MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e ZHENGZHOU UNIVERSITY   (China)

^f QUEEN SILVIA CHILDREN'S HOSPITAL   (Sweden)

^g KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Astrogliosis; Differentiation; Grafting; Neurogenesis; Radiotherapy; Transplantation

Indexed keywords

BROXURIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL COUNT; CELL FATE; CELL LABELING; CELL SURVIVAL; CONTROLLED STUDY; DENTATE GYRUS; GRANULE CELL; HIPPOCAMPUS; IONIZING RADIATION; LEARNING DISORDER; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM AND PROGENITOR CELL; NEURAL STEM CELL; NONHUMAN; PHENOTYPE; POSTNATAL CARE; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; AGING; ANIMAL; BRAIN; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CONFOCAL MICROSCOPY; CYTOLOGY; GLIOSIS; METABOLISM; NERVOUS SYSTEM DEVELOPMENT; PATHOLOGY; RADIATION DOSE; RADIATION EXPOSURE; TRANSPLANTATION; ANIMAL MODEL; EMBRYONIC STEM CELL; IRRADIATION; NEURAL STEM CELL TRANSPLANTATION;

MUS;

AGING; ANIMALS; ASTROCYTES; BRAIN; CELL DIFFERENTIATION; CELLS, CULTURED; GLIOSIS; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; NEURAL STEM CELLS; NEUROGENESIS; RADIATION DOSAGE; RADIATION, IONIZING;

EID: 84879720813     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.92     Document Type: Article

References (43)

1. Red-Horse K, Zhou Y, Genbacev O, Prakobphol A, Foulk R, McMaster M et al. Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface. J Clin Invest 2004; 114: 744-754
2. Huppertz B, Bartz C, Kokozidou M. Trophoblast fusion: Fusogenic proteins, syncytins and ADAMs, and other prerequisites for syncytial fusion. Micron 2006; 37: 509-517
3. Bhaumick B, George D, Bala RM. Potentiation of epidermal growth factor-Induced differentiation of cultured human placental cells by insulin-like growth factor-I. J Clin Endocrinol Metab 1992; 74: 1005-1011
4. Cohran V, Fang J, Milio L, Smith CH, Fant M. Type I insulin-like growth factor receptors in the BeWo choriocarcinoma cell (b30 clone) during cell differentiation. Placenta 1996; 17: 313-320
5. Crocker IP, Strachan BK, Lash GE, Cooper S, Warren AY, Baker PN. Vascular endothelial growth factor but not placental growth factor promotes trophoblast syncytialization in vitro. J Soc Gynecol Invest 2001; 8: 341-346
6. Leisser C, Saleh L, Haider S, Husslein H, Sonderegger S, Knofler M. Tumour necrosis factor-Alpha impairs chorionic gonadotrophin beta-subunit expression and cell fusion of human villous cytotrophoblast. Mol Hum Reprod 2006; 12: 601-609
7. Morrish DW, Bhardwaj D, Paras MT. Transforming growth factor beta 1 inhibits placental differentiation and human chorionic gonadotropin and human placental lactogen secretion. Endocrinology 1991; 129: 22-26
8. Seidah NG, Chretien M. Eukaryotic protein processing: Endoproteolysis of precursor proteins. Curr Opin Biotechnol 1997; 8: 602-607
9. Seidah NG, Mayer G, Zaid A, Rousselet E, Nassoury N, Poirier S et al. The activation and physiological functions of the proprotein convertases. Int J Biochem Cell Biol 2008; 40: 1111-1125
10. Seidah NG, Chretien M. Proprotein and prohormone convertases: A family of subtilases generating diverse bioactive polypeptides. Brain Res 1999; 848: 45-62
11. Zhou Z, Shen T, Zhang BH, Lv XY, Lin HY, Zhu C et al. The proprotein convertase furin in human trophoblast: Possible role in promoting trophoblast cell migration and invasion. Placenta 2009; 30: 929-938
12. Duguay SJ, Lai-Zhang J, Steiner DF. Mutational analysis of the insulin-like growth factor I prohormone processing site. J Biol Chem 1995; 270: 17566-17574
13. Lehmann M, Andre F, Bellan C, Remacle-Bonnet M, Garrouste F, Parat F et al. Deficient processing and activity of type I insulin-like growth factor receptor in the furin-deficient LoVo-C5 cells. Endocrinology 1998; 139: 3763-3771
14. Siegfried G, Basak A, Cromlish JA, Benjannet S, Marcinkiewicz J, Chretien M et al. The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. J Clin Invest 2003; 111: 1723-1732
15. Chen CP, Chen LF, Yang SR, Chen CY, Ko CC, Chang GD et al. Functional characterization of the human placental fusogenic membrane protein syncytin 2. Biol Reprod 2008; 79: 815-823
16. Cheynet V, Ruggieri A, Oriol G, Blond JL, Boson B, Vachot L et al. Synthesis, assembly, and processing of the Env ERVWE1/syncytin human endogenous retroviral envelope. J Virol 2005; 79: 5585-5593
17. Mi S, Lee X, Li X, Veldman GM, Finnerty H, Racie L et al. Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis. Nature 2000; 403: 785-789
18. Roebroek AJ, Umans L, Pauli IG, Robertson EJ, van Leuven F, Van de Ven WJ et al. Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase furin. Development 1998; 125: 4863-4876
19. Thomas G. Furin at the cutting edge: From protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol 2002; 3: 753-766
20. Scamuffa N, Siegfried G, Bontemps Y, Ma L, Basak A, Cherel G et al. Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells. J Clin Invest 2008; 118: 352-363
21. Forbes K, Westwood M. The IGF axis and placental function. a mini review. Horm Res 2008; 69: 129-137
22. Baczyk D, Drewlo S, Proctor L, Dunk C, Lye S, Kingdom J. Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast. Cell Death Differ 2009; 16: 719-727
23. Okada Y, Ueshin Y, Isotani A, Saito-Fujita T, Nakashima H, Kimura K et al. Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer. Nat Biotechnol 2007; 25: 233-237
24. Rubinstein E, Ziyyat A, Wolf JP, Le Naour F, Boucheix C. The molecular players of sperm-egg fusion in mammals. Semin Cell Dev Biol 2006; 17: 254-263
25. Vignery A. Osteoclasts and giant cells: Macrophage-macrophage fusion mechanism. Int J Exp Pathol 2000; 81: 291-304
26. Roberts L, Sebire NJ, Fowler D, Nicolaides KH. Histomorphological features of chorionic villi at 10-14 weeks of gestation in trisomic and chromosomally normal pregnancies. Placenta 2000; 21: 678-683
27. Malassine A, Frendo JL, Evain-Brion D. Trisomy 21-Affected placentas highlight prerequisite factors for human trophoblast fusion and differentiation. Int J Dev Biol 2010; 54: 475-482
28. Gauster M, Siwetz M, Orendi K, Moser G, Desoye G, Huppertz B. Caspases rather than calpains mediate remodelling of the fodrin skeleton during human placental trophoblast fusion. Cell Death Differ 2010; 17: 336-345
29. Heazell AE, Moll SJ, Jones CJ, Baker PN, Crocker IP. Formation of syncytial knots is increased by hyperoxia, hypoxia and reactive oxygen species. Placenta 2007; 28(Suppl A): S33-S40
30. Huppertz B. Placental origins of preeclampsia: Challenging the current hypothesis. Hypertension 2008; 51: 970-975
31. Yuasa K, Masuda T, Yoshikawa C, Nagahama M, Matsuda Y, Tsuji A. Subtilisin-like proprotein convertase PACE4 is required for skeletal muscle differentiation. J Biochem 2009; 146: 407-415
32. Rossant J, Cross JC. Placental development: Lessons from mouse mutants. Nat Rev Genet 2001; 2: 538-548
33. Hemberger M, Cross JC. Genes governing placental development. Trends Endocrinol Metab 2001; 12: 162-168
34. Cross JC, Nakano H, Natale DR, Simmons DG, Watson ED. Branching morphogenesis during development of placental villi. Differentiation 2006; 74: 393-401
35. Malashicheva A, Kanzler B, Tolkunova E, Trono D, Tomilin A. Lentivirus as a tool for lineage-specific gene manipulations. Genesis 2007; 45: 456-459
36. Kumasawa K, Ikawa M, Kidoya H, Hasuwa H, Saito-Fujita T, Morioka Y et al. Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model. Proc Natl Acad Sci USA 2011; 108: 1451-1455
37. Guzman-Ayala M, Ben-Haim N, Beck S, Constam DB. Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment. Proc Natl Acad Sci USA 2004; 101: 15656-15660
38. Hughes M, Dobric N, Scott IC, Su L, Starovic M, St-Pierre B et al. The Hand1, Stra13 and Gcm1 transcription factors override FGF signaling to promote terminal differentiation of trophoblast stem cells. Dev Biol 2004; 271: 26-37
39. Li H, Dakour J, Kaufman S, Guilbert LJ, Winkler-Lowen B, Morrish DW. Adrenomedullin is decreased in preeclampsia because of failed response to epidermal growth factor and impaired syncytialization. Hypertension 2003; 42: 895-900
40. Wang H, Li Q, Shao L, Zhu C. Expression of matrix metalloproteinase-2, -9, -14, and tissue inhibitors of metalloproteinase-1, -2, -3 in the endometrium and placenta of rhesus monkey (Macaca mulatta) during early pregnancy. Biol Reprod 2001; 65: 31-40
41. Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J et al. A lentivirusbased system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 2003; 33: 401-406
42. Fu J, Lv X, Lin H, Wu L, Wang R, Zhou Z et al. Ubiquitin ligase cullin 7 induces epithelial-mesenchymal transition in human choriocarcinoma cells. J Biol Chem 2010; 285: 10870-10879
43. Kawaguchi N, Sundberg C, Kveiborg M, Moghadaszadeh B, Asmar M, Dietrich N et al. ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function. J Cell Sci 2003; 116(Part 19): 3893-3904