Vascular endothelial growth factor but not placental growth factor promotes trophoblast syncytialization in vitro

Journal of the Society for Gynecologic Investigation

Volumn 8, Issue 6, 2001, Pages 341-346

  Crocker, Ian P ^a   Strachan, Bryony K ^a   Lash, Gendie E ^a   Cooper, Suzanne ^a   Warren, Averil Y ^a   Baker, Philip N ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Cytotrophoblast; Epidermal growth factor; Placental growth factor; Syncytiotrophoblast; Vascular endothelial growth factor

Indexed keywords

CYTOKERATIN 7; EPIDERMAL GROWTH FACTOR; HEMATOXYLIN; N(G) NITROARGININE METHYL ESTER; PROTEIN; VASCULOTROPIN;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL STIMULATION; CESAREAN SECTION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTROPHOBLAST; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PLACENTA; PRIORITY JOURNAL; THIRD TRIMESTER PREGNANCY;

CELL DIFFERENTIATION; ENDOTHELIAL GROWTH FACTORS; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOKINES; MICROSCOPY, FLUORESCENCE; NG-NITROARGININE METHYL ESTER; PREGNANCY; PREGNANCY PROTEINS; STATISTICS, NONPARAMETRIC; TROPHOBLASTS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0035672350     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-5576(01)00134-4     Document Type: Article

References (30)

1. Role of placenta growth factor (PIGF) in human extravillous trophoblast proliferation, migration and invasiveness
2. Vascular endothelial growth factor stimulates proliferation but not migration or invasiveness in human extravillous trophoblast
3. Hepatocyte growth factor regulates human trophoblast motility and invasion: A role for nitric oxide
4. The effects of angiogenic growth factors on extravillous trophoblast invasion and motility
5. Comparison of expression patterns for placenta growth factor, vascular endothelial growth factor (VEGF), VEGF-B and VEGF-C in the human placenta throughout gestation
6. Vascular endothelial growth factor, placenta growth factor and their receptors in isolated human trophoblast
7. Epidermal growth factor regulates trophoblast proliferation and differentiation in an autocrine/paracrine manner
8. Role of epidermal growth factor (EGF) and its receptor in the development of the human placenta
9. Role of VEGF receptor-1 (Flt-1) in mediating calcium-dependent nitric oxide release and limiting DNA synthesis in human trophoblast cells
10. Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae
11. A three-colour flow cytometry technique for measuring trophoblast intracellular antigens: The relative expression of TAP1 in human cytotrophoblast and decidual cells
12. Serum concentrations of epidermal growth factor in human pregnancy
13. Serum levels of vascular endothelial growth factor in preeclamptic and normotensive pregnancy
14. Vascular endothelial growth factor is bound in amniotic fluid and maternal serum
15. Antibody reaction patterns in first trimester placenta: Implications for trophoblast isolation and purity screening
16. Differentiation of human trophoblast cells in vitro as revealed by immunocytochemical staining of desmoplakin and nuclei
17. Expression of vascular endothelial growth factor and placenta growth factor in human placenta
18. Immunohistochemical localization of epidermal growth factor in human endometrium, decidua, and placenta
19. Vascular endothelial growth factor receptor localization and activation in human trophoblast and choriocarcinoma cells
20. Immunohistochemical localization of vascular endothelial growth factor in the human placenta
21. In vitro cultured human term cytotrophoblast: A model for normal primary epithelial cells demonstrating a spontaneous differentiation programme that requires EGF for extensive development of syncytium
22. Proliferation, differentiation and apoptosis in villous trophoblast at 13-41 weeks of gestation (including observations on annulate lamellae and nuclear pore complexes)
23. Expression of the proliferation markers Ki67 and transferrin receptor by human trophoblast populations
24. Placental apoptosis in normal human pregnancy
25. Apoptosis is a rare event in first-trimester placental tissue
26. Epidermal growth factor inhibits cytokine-induced apoptosis of primary human trophoblasts
27. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
28. A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies
29. Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor
30. Hypoxia and cAMP stimulate vascular endothelial growth factor (VEGF) in human endometrial stromal cells: Potential relevance to menstruation and endometrial regeneration