Anticancer activity and SAR studies of substituted 1,4-naphthoquinones

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 15, 2013, Pages 4662-4669

  Bhasin, Deepak ^a   Chettiar, Somsundaram N ^a   Etter, Jonathan P ^a   Mok, May ^a   Li, Pui Kai ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

1,4 Naphthoquinone; Juglone; LLL12.1; Menadione; Plumbagin; STAT3

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 2 (PHENYLAMINO)NAPHTHALENE 1,4 DIONE; 2 [(2 HYDROXYETHYL)THIO] 3 METHYLNAPHTHALENE 1,4 DIONE; 2 [(3 METHOXYPHENYL)AMINO] 3 METHYLNAPHTHALENE 1,4 DIONE; 2 [(4 METHOXYPHENYL)AMINO] 3 METHYLNAPHTHALENE 1,4 DIONE; 2 [(4 METHOXYPHENYL)AMINO]NAPHTHALENE 1,4 DIONE; 5 HYDROXY 2 [(2 HYDROXYETHYL)THIO]NAPHTHALENE 1,4 DIONE; 5 HYDROXY 3 [(2 HYDROXYETHYL)THIO] 2 METHYLNAPHTHALENE 1,4 DIONE; 5 HYDROXY 3 [(3 METHOXYPHENYL)AMINO] 2 METHYLNAPHTHALENE 1,4 DIONE; 5 HYDROXY 3 [(4 METHOXYPHENYL)AMINO] 2 METHYLNAPHTHALENE 1,4 DIONE; 5,8 DIOXO 7 (PHENYLAMINO) 5,8 DIHYDRONAPHTHALENE 1 SULFONAMIDE; 6 [(2 HYDROXYETHYL)THIO] 5,8 DIOXO 5,8 DIHYDRONAPHTHALENE 1 SULFONAMIDE; 6,7 BIS[(2 HYDROXYETHYL)THIO] 5,8 DIOXO 5,8 DIHYDRONAPHTHALENE 1 SULFONAMIDE; 7 [(3 METHOXYPHENYL)AMINO] 5,8 DIOXO 5,8 DIHYDRONAPHTHALENE 1 SULFONAMIDE; 7 [(4 METHOXYPHENYL)AMINO] 5,8 DIOXO 5,8 DIHYDRONAPHTHALENE 1 SULFONAMIDE; 8 HYDROXY 2 (PHENYLAMINO)NAPHTHALENE 1,4 DIONE; 8 HYDROXY 2 [(2 HYDROXYETHYL)THIO]NAPHTHALENE 1,4 DIONE; 8 HYDROXY 2 [(3 METHOXYPHENYL)AMINO]NAPHTHALENE 1,4 DIONE; 8 HYDROXY 2 [(4 METHOXYPHENYL)AMINO]NAPHTHALENE 1,4 DIONE; JUGLONE; MENADIONE; PLUMBAGIN; STAT3 PROTEIN; SULFONAMIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIMERIZATION; DRUG DESIGN; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; FLUORESCENCE ANALYSIS; IC 50; PROSTATE CANCER; STRUCTURE ACTIVITY RELATION;

EID: 84879696191     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.05.017     Document Type: Article

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