Synthesis, characterization, molecular docking and cytotoxic activity of novel plumbagin hydrazones against breast cancer cells

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 9, 2012, Pages 3104-3108

  Dandawate, Prasad ^a   Khan, Ejazuddin ^a   Padhye, Subhash ^a,b   Gaba, Himanshi ^c   Sinha, Swati ^c   Deshpande, Jyoti ^c   Venkateswara Swamy, K ^c   Khetmalas, Madhukar ^c   Ahmad, Aamir ^b   Sarkar, Fazlul H ^b  

^a DR D Y PATIL DENTAL COLLEGE AND HOSPITAL   (India)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DR D Y PATIL BIOTECHNOLOGY AND BIOINFORMATICS INSTITUTE   (India)

Author keywords

Breast cancer; NF B; Plumbagin hydrazone; Triple negative breast cancer

Indexed keywords

DASATINIB; ESTROGEN RECEPTOR; ETOPOSIDE; GEFITINIB; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IXABEPILONE; OLAPARIB; PLUMBAGIN; PLUMBAGIN HYDRAZONE DERIVATIVE; UNCLASSIFIED DRUG; VELIPARIB;

ARTICLE; BREAST CANCER; DRUG CYTOTOXICITY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HYDROGEN BOND; MOLECULAR DOCKING; TRIPLE NEGATIVE BREAST CANCER;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BINDING SITES; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HUMANS; HYDRAZONES; HYDROGEN BONDING; NAPHTHOQUINONES; NF-KAPPA B; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84859826209     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.03.060     Document Type: Article

References (35)

1. R. Siegel, E. Ward, O. Brawley, and A. Jemal CA Cancer J. Clin. 61 2011 212
2. B.J. Deroo, and K.S. Korach J. Clin. Invest. 116 2006 561
3. W.J. Irvin Jr., and L.A. Carey Eur. J. Cancer 44 2008 2799
4. F. Podo, L.M. Buydens, H. Degani, R. Hilhorst, E. Klipp, I.S. Gribbestad, H.S. Van, H.W. van Laarhoven, J. Luts, D. Monleon, G.J. Postma, N. Schneiderhan-Marra, F. Santoro, H. Wouters, H.G. Russnes, T. Sorlie, E. Tagliabue, and A.L. Borresen-Dale Mol. Oncol. 4 2010 209
5. M. De Laurentiis, D. Cianniello, R. Caputo, B. Stanzione, G. Arpino, S. Cinieri, V. Lorusso, and P.S. De Cancer Treat. Rev. 36 2010 S80
6. J.M. Hall, M.K. Lee, B. Newman, J.E. Morrow, L.A. Anderson, B. Huey, and M.C. King Science 250 1990 1684
7. R. Wooster, G. Bignell, J. Lancaster, S. Swift, S. Seal, J. Mangion, N. Collins, S. Gregory, C. Gumbs, and G. Micklem Nature 378 1995 789
8. A.R. Venkitaraman Cell 108 2002 171
9. S.R. Lakhani, D.V. Van, J. Jacquemier, T.J. Anderson, P.P. Osin, L. McGuffog, and D.F. Easton J. Clin. Oncol. 20 2002 2310
10. M. Leung, D. Rosen, S. Fields, A. Cesano, and D.R. Budman Mol. Med. 17 2011 854
11. T. Byrski, T. Huzarski, R. Dent, J. Gronwald, D. Zuziak, C. Cybulski, J. Kladny, B. Gorski, J. Lubinski, and S.A. Narod Breast Cancer Res. Treat. 115 2009 359
12. T. Byrski, J. Gronwald, T. Huzarski, E. Grzybowska, M. Budryk, M. Stawicka, T. Mierzwa, M. Szwiec, R. Wisniowski, M. Siolek, R. Dent, J. Lubinski, and S. Narod J. Clin. Oncol. 28 2010 375
13. Padhye, S.; Dandawate, P.; Yusufi, M.; Ahmad, A.; Sarkar, F. H. Med. Res. Rev. 2010 [Epub Ahead of Print]. PMID:21064184, doi: http://dx.doi.org/10.1002/ med.20235.
14. A. Ahmad, S. Banerjee, Z. Wang, D. Kong, and F.H. Sarkar J. Cell Biochem. 105 2008 1461
15. J.C. Tilak, S. Adhikari, and T.P. Devasagayam Redox. Rep. 9 2004 219
16. R. Checker, D. Sharma, S.K. Sandur, S. Khanam, and T.B. Poduval Int. Immunopharmacol. 9 2009 949
17. M.H. Aziz, N.E. Dreckschmidt, and A.K. Verma Cancer Res. 68 2008 9024
18. S. Sharma, B.K. Sharma, and Y.S. Prabhakar Eur. J. Med. Chem. 44 2009 2847
19. J.P. Dzoyem, J.G. Tangmouo, D. Lontsi, F.X. Etoa, and P.J. Lohoue Phytother. Res. 21 2007 671
20. A.A. Powolny, and S.V. Singh Pharm. Res. 25 2008 2171
21. K.A. Thasni, S. Rakesh, G. Rojini, T. Ratheeshkumar, G. Srinivas, and S. Priya Ann. Oncol. 19 2008 696
22. K.C. Ravindra, B.R. Selvi, M. Arif, B.A. Reddy, G.R. Thanuja, S. Agrawal, S.K. Pradhan, N. Nagashayana, D. Dasgupta, and T.K. Kundu J. Biol. Chem. 284 2009 24453
23. B. Hazra, R. Sarkar, S. Bhattacharyya, P.K. Ghosh, G. Chel, and B. Dinda Phytother. Res. 16 2002 133
24. K. Ogihara, R. Yamashiro, M. Higa, and S. Yogi Chem. Pharm. Bull. 45 1997 437
25. D.W. Gammon, D.J. Steenkamp, V. Mavumengwana, M.J. Marakalala, T.T. Mudzunga, R. Hunter, and M. Munyololo Bioorg. Med. Chem. 18 2010 2501
26. N.K.B. Adikaram, V. Karunaratne, B.M.R. Bandara, C.M. Hewage, C. Abayasekara, and B.S.S. Mendis J. Natn. Sci. Foundation Sri Lanka 30 2002 89
27. L. Salmon-Chemin, E. Buisine, V. Yardley, S. Kohler, M.A. Debreu, V. Landry, C. Sergheraert, S.L. Croft, R.L. Krauth-Siegel, and E. vioud-Charvet J. Med. Chem. 44 2001 548
28. C.R. Joshi, G.S. Jagtap, and S.V. Chalgeri Ind. J. Pharm. Sci. 50 1988 107
29. A.C.M. Dangalla, and O.A. Ileperuma J. Nat. Sci. Coan. Sri Lanka 13 1985 141
30. Z.F. Chen, M.X. Tan, L.M. Liu, Y.C. Liu, H.S. Wang, B. Yang, Y. Peng, H.G. Liu, H. Liang, and C. Orvig Dalton Trans. 2009 10824
31. Z.F. Chen, M.X. Tan, Y.C. Liu, Y. Peng, H.H. Wang, H.G. Liu, and H. Liang J. Inorg. Biochem. 105 2011 426
32. Q.X. Li, H.A. Tang, Y.Z. Li, M. Wang, L.F. Wang, and C.G. Xia J. Inorg. Biochem. 78 2000 167
33. V. Pande, R.K. Sharma, J. Inoue, M. Otsuka, and M.J. Ramos J. Comput. Aided Mol. Des 17 2003 825
34. Y.F. Xia, B.Q. Ye, Y.D. Li, J.G. Wang, X.J. He, X. Lin, X. Yao, D. Ma, A. Slungaard, R.P. Hebbel, N.S. Key, and J.G. Geng J. Immunol. 173 2004 4207
35. K.M. Chen, T.E. Spratt, B.A. Stanley, D.A. De Cotiis, M.C. Bewley, J.M. Flanagan, D. Desai, A. Das, E.S. Fiala, S. Amin, and K. El-Bayoumy Cancer Res. 67 2007 10475